推拿联合椎间孔镜治疗腰椎间盘突出症临床观察

目的 探讨推拿干预下经皮椎间孔镜技术治疗腰椎间盘突出症的近期临床疗效。方法 选取2020年6月—2022年2月广西壮族自治区脑科医院80例符合经皮椎间孔镜手术治疗条件的腰椎间盘突出症患者,随机分为对照组和治疗组,每组40例,对照组单独予以椎间孔镜手术治疗,治疗组在对照组的基础上予以推拿干预治疗,记录2组术前、术后1、7 d及术后6个月的腰腿痛视觉模拟评分(Visual Analogue Scale, VAS)及Oswestry功能障碍指数(Oswestry Disability Index, ODI),术后终末期随访按照腰椎管狭窄的疗效评定标准(Macnab标准)评价总体优良率。结果 手术前,2组VAS评分和ODI指数差异无统计学意义(P>0.05),2组内术后1、7 d及术后6个月VAS评分和ODI指数与术前比较,差异有统计学意义(P<0.05)。2组间术后1、7 d的VAS评分和ODI指数比较,差异有统计学意义(P<0.05);2组间术后6个月VAS评分和ODI指数比较,差异无统计学意义(P>0.05)。终末期随访按照Macnab标准评价总体优良率差异无统计...     

椎间盘镜手术系统治疗中老年腰椎间盘突出症的临床效果观察

目的探讨采用椎间盘镜手术系统(MED)对中老年腰椎间盘突出症患者的治疗效果。方法回顾性分析我院骨科2010年2月至2013年4月收治的100例腰椎间盘突出症患者的临床诊治资料。根据手术方式分为经皮内镜下腰椎间盘突出切除术44例(对照组)、采用MED治疗56例(MED组),比较两组患者的术中情况,术前及术后12个月、术后24个月的视觉模拟疼痛评分(VAS)、Oswestry功能障碍指数及Nakia疗效评价情况。结果对照组的手术时间明显短于MED组(P<0.05),而MED组患者的术中出血量、卧床时间、住院时间明显短于对照组(P<0.05)。术前两组患者的VAS、ODI评分差异均无统计学意义(P>0.05),两组患者术后第12个月、24个月的VAS、ODI评分均较术前明显好转(P<0.05),但术后两组患者的ODI评分差异无统计学意义(P>0.05),术后MDE组的VAS评分在第12个月、24个月均显著优于对照组(P<0.01)。术后两组患者的Nakia疗效分布及总有效率比较差异无统计学意义(P>0.05)。结论椎间盘镜手术系统治疗中老年腰椎间盘突出症患者较经皮内镜下腰椎间盘突切除术具有减少患者术中出血量、住院时间、卧床时间、术后疼痛的优势,同时治疗效果良好。     

桦褐孔菌粗多糖的精制方法探讨

目的研究比较桦褐孔菌粗多糖的不同除蛋白方法,评价粗多糖的精制方法。方法分别采用硫酸-蒽酮法和考马斯亮蓝法测定粗多糖和精制多糖中多糖含量和蛋白质含量;测定波长分别为625nm和595nm;以多糖保留率和蛋白去除率为双重指标,比较Sevag法、三氯乙酸法和酶法的除蛋白效果。结果 Sevag法多糖保留率72.9%,蛋白去除率9.5%;三氯乙酸法多糖保留率13.3%,蛋白去除率96.0%;酶法多糖保留率46.9%,蛋白去除率43.8%。结论 Sevag法的多糖保留率最高,三氯乙酸法的蛋白去除率最高。     

经皮椎体后凸与经皮椎体成形术修复骨质疏松椎体压缩性骨折：随机分组比较

BACKGROUND: Recent literatures have showed that percutaneous kyphoplasty can effectively avoid nerve damage, pulmonary embolism, and insufficient vertebral height and other security risks when bone cement is infused into affected vertebrae in percutaneous vertebroplasty. OBJECTIVE: To compare the effect of percutaneous kyphoplasty and percutaneous vertebroplasty in repair of osteoporotic vertebral compression fractures. METHODS: A total of 106 patients with senile osteoporotic vertebral compression fractures were randomly divided into trial group and control group (n=53 per group). Patients in the trial group were treated with percutaneous kyphoplasty, and those in the control group treated with percutaneous vertebroplasty. All patients were followed up for 6 months after repair. The vertebral compression deformation, bone cement distribution, midline vertebral bone cement condition, vertebral height restoration, bone cement leakage, vertebral kyphosis, progressive spinal collapse, nerve damage, as well as visual analog scale scores and Oswestry disability index scores in these two groups were compared. RESULTS AND CONCLUSION: Compared with the control group, there was less bone cement leakage and vertebral compression deformation in the trial group. Moreouer, in the trial group, bone cement distributed uniformly, vertebral height restoration was good and effective, pain was obviously relieved, and the probability of vertebral kyphosis, progressive spine collapse and nerve damage was significantly reduced (all P < 0.05). These results suggest that percutaneous kyphoplasty can effectively relieve the pain of patients with osteoporotic vertebral compression fractures, restore vertebral body height and reduce the incidence of complications, which effectively guarantees the postoperative restoration of motor function.