Association of Ureaplasma urealyticum colonization with development of bronchopulmonary dysplasia: A systemic review and meta-analysis

There is controversy regarding the roles of Ureaplasma urealyticum （U. urealyticum） colo- nization in the development of hronchopulmonary dysplasia （BPD）. This study explored the association between U. urealyticum and bronchopulmonary dysplasia at 36 weeks post-menstrual age （BPD36）. Studies published before December 31, 2013 were searched from Medline, Embase, Ovid, Web of Sci- ence, and Cochrane databases, with the terms ＂Ureaplasma urealyticum＂, ＂chronic lung disease＂, or ＂BPD36＂ used, and English language as a limit. The association between U. urealyticum colonization and BPD36 was analyzed with RevMan 4.2.10 software, using the odds ratio （OR） and relative risk （RR） for dichotomous variables. Out of the enrolled 81 studies, 11 investigated the BPD36 in total 1193 in- fants. Pooled studies showed no association between U. urealyticum colonization and subsequent de- velopment of BPD36, with the OR and RR being 1.03 （95% CI=0.78-1.37; P=-0.84） and 1.01 （95% CI= 0.88-1.16, P=-0.84）, respectively. These findings indicated no association between U. urealyticum colo- nization and the development of BPD36.     

腹腔镜输尿管输尿管端侧吻合术在小儿重复肾中的应用

目的 探讨腹腔镜输尿管输尿管端侧吻合术治疗小儿重复肾的安全性和有效性。方法 回顾性分析2020年6月～2021年12月9例重复肾上组肾积水行腹腔镜输尿管输尿管端侧吻合术的临床资料。年龄3个月～8岁(中位年龄7个月)。左侧6例，右侧2例，1例双侧重复肾伴左侧上组肾积水。2例术前检查提示上组肾对应输尿管异位开口于阴道或膀胱颈部，6例伴输尿管末端膨出。先行膀胱镜检查及患侧下组肾输尿管内双J管置入，于下组肾输尿管远端行腹腔镜输尿管输尿管端侧吻合。结果 9例均顺利完成腹腔镜手术，无中转开放手术。术中无并发症，术中出血量<10 ml。手术时间180～240(202.2±21.1)min。住院时间7～10(8.5±0.9)d。术后4～6周拔除双J管，2例双J管留置期间尿路感染。9例术后随访6～21(11.7±5.1)月，复查超声均提示上组肾积水较前减轻，7例上组肾扩张的输尿管直径较前缩小。一例8岁女性患儿术前输尿管异位开口存在尿失禁，术后症状完全消失。结论 初步经验表明腹腔镜输尿管输尿管端侧吻合术对小儿重复肾是一种安全、有效的术式选择。