全文获取类型
收费全文 | 987篇 |
免费 | 77篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 18篇 |
妇产科学 | 22篇 |
基础医学 | 139篇 |
口腔科学 | 8篇 |
临床医学 | 89篇 |
内科学 | 224篇 |
皮肤病学 | 47篇 |
神经病学 | 77篇 |
特种医学 | 14篇 |
外科学 | 123篇 |
综合类 | 6篇 |
预防医学 | 66篇 |
眼科学 | 85篇 |
药学 | 61篇 |
中国医学 | 2篇 |
肿瘤学 | 77篇 |
出版年
2023年 | 6篇 |
2022年 | 8篇 |
2021年 | 33篇 |
2020年 | 21篇 |
2019年 | 40篇 |
2018年 | 38篇 |
2017年 | 28篇 |
2016年 | 38篇 |
2015年 | 41篇 |
2014年 | 45篇 |
2013年 | 60篇 |
2012年 | 91篇 |
2011年 | 83篇 |
2010年 | 58篇 |
2009年 | 52篇 |
2008年 | 58篇 |
2007年 | 58篇 |
2006年 | 61篇 |
2005年 | 42篇 |
2004年 | 38篇 |
2003年 | 32篇 |
2002年 | 32篇 |
2001年 | 21篇 |
2000年 | 20篇 |
1999年 | 9篇 |
1998年 | 2篇 |
1997年 | 3篇 |
1995年 | 1篇 |
1994年 | 1篇 |
1993年 | 2篇 |
1992年 | 3篇 |
1991年 | 5篇 |
1990年 | 3篇 |
1989年 | 7篇 |
1988年 | 3篇 |
1987年 | 2篇 |
1986年 | 5篇 |
1985年 | 3篇 |
1983年 | 4篇 |
1982年 | 1篇 |
1979年 | 1篇 |
1970年 | 1篇 |
1969年 | 1篇 |
1968年 | 1篇 |
1967年 | 2篇 |
排序方式: 共有1064条查询结果,搜索用时 265 毫秒
1.
2.
3.
4.
5.
6.
7.
8.
9.
Mosayeb Rostamian Roya Chegene Lorestani Somayeh Jafari Rezvan Mansouri Shahab Rezaeian Keyghobad Ghadiri Alisha Akya 《Indian journal of medical microbiology》2022,40(3):323-329
BackgroundNeisseria meningitidis is one of the most important causes of meningitis and pathogens-associated deaths in developing and developed countries. Effective anti-microbial agents are pivotal to treat and control N. meningitidis infections. The aim of the present study was to systematically review published studies on the antibiotic resistance of N. meningitidis in the last 20 years (2000–2020) in the world.MethodsPublished researches were identified through a literature search using reputable databases including PubMed, Scopus, and Web of Science. Finally, 24 studies were included for a random-effects model meta-analysis.ResultsThe overall resistance to most commonly used antibiotics such as ceftriaxone, cefotaxime, ciprofloxacin and rifampin was low, ranging from 1 to 3.4%. However, non-sensitivity to penicillin, as the first-line antibiotic against N. meningitidis, was higher (27.2%). Altogether, the resistance to the first-line antibiotics (except penicillin) is still low indicating these drugs are effective against meningococcal meningitis. We also found a significant gap between MIC and disk diffusion for evaluating resistance to antibiotics in which disk diffusion overestimate the resistance rate.ConclusionsTo properly management and prevent the spread of N. miningitidis isolates resistant antibiotics, it is necessary to monitor the pattern of antibiotic susceptibility regionally and globally using the MIC methods. 相似文献
10.
Cefepime is active against bacteria producing chromosomally and plasmid-mediated extended broad-spectrum β-lactamase enzymes. The aim of this study was to evaluate risk factors for acquisition of cefepime resistance in Escherichia coli strains among hospitalized patients in a university hospital in Sanandaj, Iran. The study was a case-control investigation. A case patient was defined as a patient who had one isolate of a cefepime-resistant E. coli strain. A control patient was defined as a patient who had one isolate of a cefepime-sensitive E. coli strain. Cefepime resistance was determined by HiComb MIC tests (HIMEDIA, India). Out of the 255 total isolates, 73 (28.6%) were resistant to cefepime. The previous treatment of cefepime was a risk factor for acquisition of a cefepime-resistant isolate (OR = 6.32, 95% CI: 1.5-25.19, p < 0.007). The use of a ventilator was considered to be a risk for acquisition of a cefepime-resistant isolate (OR = 6.25, 95% CI: 1.86-21.02, p <0.002). The use of a catheter was also found to be a risk factor for acquisition of cefepime resistance (OR = 6.28, 95% CI: 1.86-21.02, p <0.001). There was a significant correlation between days of stay in hospital wards and cefepime resistance (p < 0.003). The main risk factors associated with cefepime resistance were previous treatment with cefepime, use of ventilator, use of catheter and days of stay in ward. More studies are needed to evaluate the role of these factors in order to control the spread of drug resistance. 相似文献