全文获取类型
收费全文 | 1151435篇 |
免费 | 70500篇 |
国内免费 | 1423篇 |
专业分类
耳鼻咽喉 | 14731篇 |
儿科学 | 32141篇 |
妇产科学 | 27035篇 |
基础医学 | 156843篇 |
口腔科学 | 30258篇 |
临床医学 | 96577篇 |
内科学 | 222585篇 |
皮肤病学 | 20406篇 |
神经病学 | 92207篇 |
特种医学 | 47475篇 |
外国民族医学 | 79篇 |
外科学 | 189727篇 |
综合类 | 21041篇 |
现状与发展 | 1篇 |
一般理论 | 272篇 |
预防医学 | 83083篇 |
眼科学 | 24559篇 |
药学 | 85150篇 |
3篇 | |
中国医学 | 2797篇 |
肿瘤学 | 76388篇 |
出版年
2019年 | 6838篇 |
2018年 | 32868篇 |
2017年 | 26069篇 |
2016年 | 29917篇 |
2015年 | 10733篇 |
2014年 | 14130篇 |
2013年 | 20000篇 |
2012年 | 33599篇 |
2011年 | 49426篇 |
2010年 | 35378篇 |
2009年 | 27777篇 |
2008年 | 48042篇 |
2007年 | 52603篇 |
2006年 | 28953篇 |
2005年 | 30176篇 |
2004年 | 30770篇 |
2003年 | 31276篇 |
2002年 | 28404篇 |
2001年 | 55322篇 |
2000年 | 57406篇 |
1999年 | 47401篇 |
1998年 | 11296篇 |
1997年 | 10001篇 |
1996年 | 9478篇 |
1995年 | 9201篇 |
1994年 | 8585篇 |
1993年 | 7842篇 |
1992年 | 35665篇 |
1991年 | 34148篇 |
1990年 | 32969篇 |
1989年 | 32057篇 |
1988年 | 29134篇 |
1987年 | 28403篇 |
1986年 | 26406篇 |
1985年 | 25279篇 |
1984年 | 17939篇 |
1983年 | 15242篇 |
1982年 | 7927篇 |
1979年 | 15880篇 |
1978年 | 10670篇 |
1977年 | 9059篇 |
1976年 | 7946篇 |
1975年 | 8633篇 |
1974年 | 10503篇 |
1973年 | 9867篇 |
1972年 | 9360篇 |
1971年 | 8861篇 |
1970年 | 8452篇 |
1969年 | 7963篇 |
1968年 | 7232篇 |
排序方式: 共有10000条查询结果,搜索用时 312 毫秒
1.
Hassen Lena M. Albarrak Rana A. Albahlal Reem A. Alsaqabi Dimah K. Hassen Ikhlass M. Daghestani Maha H. Alqurtas Eman M. Alkhalaf Abdulaziz T. Bedaiwi Mohammed K. Omair Mohammed A. Almaghlouth Ibrahim A. 《Quality of life research》2022,31(11):3229-3239
Quality of Life Research - The COVID-19 pandemic might add to the stressors experienced by people living with rheumatic diseases. This study aimed to examine rheumatic patients’ functional... 相似文献
2.
3.
Kevin Kyung Ho Choi Santosh Sanagapalli 《World journal of gastrointestinal oncology》2022,14(3):568-586
Barrett's esophagus (BE) is the precursor to esophageal adenocarcinoma (EAC). Progression to cancer typically occurs in a stepwise fashion through worsening dysplasia and ultimately, invasive neoplasia. Established EAC with deep involvement of the esophageal wall and/or metastatic disease is invariably associated with poor long-term survival rates. This guides the rationale of surveillance of Barrett’s in an attempt to treat lesions at an earlier, and potentially curative stage. The last two decades have seen a paradigm shift in management of Barrett’s with rapid expansion in the role of endoscopic eradication therapy (EET) for management of dysplastic and early neoplastic BE, and there have been substantial changes to international consensus guidelines for management of early BE based on evolving evidence. This review aims to assist the physician in the therapeutic decision-making process with patients by comprehensive review and summary of literature surrounding natural history of Barrett’s by histological stage, and the effectiveness of interventions in attenuating the risk posed by its natural history. Key findings were as follows. Non-dysplastic Barrett’s is associated with extremely low risk of progression, and interventions cannot be justified. The annual risk of cancer progression in low grade dysplasia is between 1%-3%; EET can be offered though evidence for its benefit remains confined to highly select settings. High-grade dysplasia progresses to cancer in 5%-10% per year; EET is similarly effective to and less morbid than surgery and should be routinely performed for this indication. Risk of nodal metastases in intramucosal cancer is 2%-4%, which is comparable to operative mortality rate, so EET is usually preferred. Submucosal cancer is associated with nodal metastases in 14%-41% hence surgery remains standard of care, except for select situations. 相似文献
4.
5.
Phoebe Hammer Kevin White Stephanie Mengden Vessy Korcheva Philipp W. Raess 《Journal of cutaneous pathology》2019,46(5):343-346
Cutaneous leiomyomas are rare benign smooth‐muscle tumors. These lesions are distinguished based on their cell of origin and are subclassified as pilar leiomyoma, angioleiomyoma, and genital‐type leiomyoma. Nipple leiomyoma is the least common genital‐type leiomyoma, arising from the dartoic muscle cell of the nipple. Histologic examination of the lesion is necessary for definitive diagnosis, and these uncommon tumors can pose a diagnostic challenge. We describe herein a series of six nipple leiomyomas with a spectrum of histologic appearances. 相似文献
6.
Joshua J. Bear Heidi E. Kirsch Brian D. Berman Kevin E. Chapman Jason R. Tregellas 《Epileptic Disord》2020,22(3):291-299
Aims. Functional connectivity is providing new insights into the network nature of epilepsy with growing clinical applications. Our objective was to validate a novel magnetoencephalography‐based method to non‐invasively measure the epileptic network. Methods. We retrospectively identified pediatric and adult patients with refractory focal epilepsy who underwent pre‐surgical magnetoencephalography with subsequent intracranial electrographic monitoring. Magnetoencephalography tracings were visually reviewed, and interictal epileptiform discharges (“spikes”) were individually marked. We then evaluated differences in whole‐brain connectivity during brief epochs preceding the spikes and during the spikes using the Network‐Based Statistic to test differences at the network level. Results. In six patients with statistically‐significant network differences, we observed substantial overlap between the spike‐associated networks and electrographically active areas identified during intracranial monitoring (the spike‐associated network was 78% and 83% sensitive for intracranial electroencephalography‐defined regions in the irritative and seizure onset zones, respectively). Conclusion. These findings support the neurobiological validity of the spike‐associated network method. Assessment of spike‐associated networks has the potential to improve surgical planning in epilepsy surgery patients by identifying components of the epileptic network prior to implantation. 相似文献
7.
Rupa Narayan MD Traci M. Blonquist MS Ashkan Emadi MD PhD Robert P. Hasserjian MD Meghan Burke BS Christopher Lescinskas BS Donna S. Neuberg ScD Andrew M. Brunner MD Gabriela Hobbs MD Hanno Hock MD PhD Steven L. McAfee MD Yi-Bin Chen MD Eyal Attar MD Timothy A. Graubert MD Christina Bertoli MSN Jenna A. Moran MSN Meghan K. Bergeron MSN Julia E. Foster MSN Aura Y. Ramos BSN Tina T. Som BSN Megan K. Vartanian BSN RN Jennifer L. Story LPN Kristin McGregor MS Molly Macrae BS Tanya Behnan BS Margaret C. Wey PhD Jessica Rae BSN Frederic I. Preffer PhD Patricia Lesho BA Vu H. Duong MD Mason L. Mann BA Karen K. Ballen MD Christine Connolly BS Philip C. Amrein MD Amir T. Fathi MD 《Cancer》2020,126(6):1264-1273
8.
Brittney H. Cotta Margaret F. Meagher Aaron Bradshaw Stephen T. Ryan Gerant Rivera-Sanfeliz 《Expert review of anticancer therapy》2019,19(4):301-308
Introduction: Percutaneous renal mass biopsy has evolved over the last decade with improvements on previous pitfalls including low tissue yield, high non-diagnostic rates, and complications. As understanding of tumor biology and natural history of renal cortical neoplasms has improved, percutaneous renal mass biopsy is poised to have an expanding role in an area characterized by individualized management and refined risk stratification.
Areas covered: This review summarizes the evolution of renal mass biopsy to its current state with respect to outcomes, indications, and clinical guidelines.
Expert opinion: With improved understanding of differential biological potential of renal cortical neoplasms combined with technical improvements in diagnostic yield and accuracy, utilization of renal mass biopsy is becoming an important adjunct to patient care in a broad range of clinical scenarios, including active surveillance, thermal ablation, and use of primary systemic therapy in localized and advanced settings. 相似文献
9.
10.