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Mehmet Salih Aydin Aydemir Kocarslan Sezen Kocarslan Ahmet Kucuk ?rfan Eser Hatice Sezen Evren Buyukfirat Abdussemet Hazar 《Brazilian Journal Of Cardiovascular Surgery》2015,30(1):77-83
Introduction
Previous studies have demonstrated that thymoquinone has protective effects against ischemia reperfusion injury to various organs like lungs, kidneys and liver in different experimental models.Objective
We aimed to determine whether thymoquinone has favorable effects on lung, renal, heart tissues and oxidative stress in abdominal aorta ischemia-reperfusion injury.Methods
Thirty rats were divided into three groups as sham (n=10), control (n=10) and thymoquinone (TQ) treatment group (n=10). Control and TQ-treatment groups underwent abdominal aorta ischemia for 45 minutes followed by a 120-min period of reperfusion. In the TQ-treatment group, thymoquinone was given 5 minutes. before reperfusion at a dose of 20 mg/kg via an intraperitoneal route. Total antioxidant capacity, total oxidative status (TOS), and oxidative stress index (OSI) in blood serum were measured and lung, kidney, and heart tissue histopathology were evaluated with light microscopy.Results
Total oxidative status and oxidative stress index activity in blood samples were statistically higher in the control group compared to the sham and TQ-treatment groups (P<0.001 for TOS and OSI). Control group injury scores were statistically higher compared to sham and TQ-treatment groups (P<0.001 for all comparisons).Conclusion
Thymoquinone administered intraperitoneally was effective in reducing oxidative stress and histopathologic injury in an acute abdominal aorta ischemia-reperfusion rat model. 相似文献2.
Dursun Mehmet Emin Erdem Seyfettin Karahan Mine Ava Sedat Hazar Leyla Dursun Birgül Keklikçi Uğur 《Lasers in medical science》2022,37(2):1147-1154
Lasers in Medical Science - Using optical coherence tomography angiography (OCTA), we sought to evaluate parafoveal vascular density (VD) in patients with central serous chorioretinopathy (CSCR).... 相似文献
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Gul Yahya Kapakli Hasan Guner Sukru Nail Alan Havva Bozkurt Hazar Esra Keles Sevgi Reisli Ismail 《Journal of clinical immunology》2022,42(1):64-71
Journal of Clinical Immunology - The aim was to review the compliance, side effects and effectiveness of subcutaneous immunoglobulin (SCIG) supplementation in patients with primary... 相似文献
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Hanifah AL Ismail SH Ming HT 《The Southeast Asian journal of tropical medicine and public health》2010,41(5):1082-1087
Four commercial repellents were evaluated in the laboratory against Leptotrombidium deliense chiggers. Both in vitro and in vivo methods were used to determine repellency of the compounds. The repellents were Kellis (containing citronella oil, jojoba oil and tea tree oil), Kaps (containing citronella oil), BioZ (containing citronella oil, geranium oil and lemon grass oil) and Off (containing DEET). The combination of three active ingredients: citronella oil, geranium oil, lemon grass oil gave the highest repellency (87%) followed by DEET (84%). In vitro repellencies ranged from 73% to 87%. There was no significant difference between the four products. All the repellents had 100% in vivo repellency compared to 41-57% for the controls. 相似文献
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