手术患者焦虑程度评估及对策

2001年8月～2003年12月，我院手术室为解除或减轻病人焦虑情绪，对1500例患实施了术前心理护理，并对60例不同病种的手术患进行焦虑程度评估。现报告如下。     

关节腔灌洗联合康复训练对膝骨性关节炎疗效的影响

目的 探讨关节腔灌洗联合康复训练对膝骨性关节炎疗效的影响。方法 将82例膝骨性关节炎患者随机分为观察组和对照组各41例，对照组采用关节腔灌洗后予以常规护理，观察组在此基础上予以早期功能锻炼。采用目测类比定级法（VAS和膝关节日常活动（ADL）能力评分，比较患者治疗前后患膝疼痛程度并对膝关节日常活动（ADL）能力进行评定。结果 治疗30d后，两组患者症状均减轻，但观察组VAS及ADL能力评分显著优于对照组（均P〈0．01）。结论 关节腔灌洗联合康复训练可明显提高膝骨性关节炎患者的日常活动能力，并减轻疼痛。     

卡介菌多糖核酸注射液和特异性免疫治疗对哮喘的疗效

目的研究卡介菌多糖核酸（BCG-PNA）和特异性免疫治疗（SIT）对哮喘患儿肺功能、血清IgE和分泌细胞因子的影响。方法用BCG-PNA和SIT治疗哮喘患儿45例，治疗前后检测肺功能，酶联免疫吸附试验检测血清IgE和外周血单个核细胞分泌细胞因子IL-4、IFN-γ、IL-13、IL-12水平。结果BCG-PNA和SIT明显改善哮喘患儿的用力肺活量、第1秒用力呼气容量、25％最大呼气流量等指标，降低血清IgE，抑制IL-4、IL-13分泌，促进IFN-γ、IL-12产生，两者联合治疗对于降低IL-13、增加IFN-γ产生有协同作用。结论BCG-PNA和SIT能改善哮喘患儿肺功能，增强Th1反应，降低Th2应答，调节Th1／Th2平衡。两者联合治疗对改善哮喘患儿失衡的细胞因子网络有一定协同作用。     

布地奈德混悬液雾化吸入治疗毛细支气管炎46例疗效观察

目的:了解布地奈德混悬液雾化吸入治疗毛细支气管炎的临床疗效.方法:92例毛细支气管炎患儿随机分为治疗组和对照组各46例.治疗组在常规综合治疗基础上给予雾化吸入布地奈德混悬液1 mg,2次/d,疗程3~5 d,对照组常规综合治疗.结果:治疗组总有效率91.2%,对照组总有效率80.4%,两组总有效率比较差异有统计学意义(...     

干扰素α1b治疗儿童手足口病临床疗效分析

目的了解干扰素治疗儿童手足口病的临床疗效。方法对235倒手足口病志儿进行随机分组。治疗组126例给予干扰素,对照组109例给予利巴韦林钟。结果干扰素在治疗手足口病时,其退热及退疹时间,显效情况均优于对照组。结论干扰素治疗手足口病的总有效率明显优于病毒唑,不良反应不明显,值得推广童用。     

皮下快速注射免疫球蛋白在儿童中的应用

替代性静脉内(IVIG)注射免疫球蛋白是原发性抗体缺乏的标准疗法。对于每2～3周一次的注射,必须有可靠的静脉通路,但对小儿这却是一个棘手的问题。皮下快速注射免疫球蛋白(SCIG)已成功地用于成人,本文是用于儿童的首次报道。 4名儿童(年龄1、3、8及14岁)患反复发作的细菌感染。其中3名儿童的血清免疫球     

卡介苗在哮喘特异性免疫治疗中的潜在意义

大量研究证实哮喘是一种慢性气道炎症性疾病,有T淋巴细胞、嗜酸性粒细胞(Eos)、肥大细胞和中性粒细胞等炎症细胞参与其发病,其中T淋巴细胞及其分泌的细胞因子在气道慢性炎症中发挥重要作用,主要表现在T辅助细胞(Th)亚群功能失调.     

Clinical observation on electroacupuncture plus hydro-acupuncture for low back pain caused by compression fractures

Objective

To observe the effect of electroacupuncture (EA) at Jiaji (EX-B 2) points plus hydro-acupuncture with sinomenine hydrochloride for low back pain caused by compression fractures in the elderly.

Methods

Ninety-five elderly in-patients with low back pain caused by compression fractures were randomly divided into an observation group and an EA group according to the visit sequence. Both groups received the same basic treatment. In the EA group, 48 cases were treated with EA at Jiaji (EX-B 2) points plus the basic therapy; 47 cases in the observation group received the basic treatment plus EA and hydro-acupuncture with sinomenine hydrochloride at Jiaji (EX-B 2) points. The levels of osteoprotegerin (OPG) and interleukin-1β (IL-1β) in peripheral blood were measured by enzyme-linked immunosorbent assay (ELISA) before and at the 21st day of treatment in both groups. Oswestry disability index (ODI) and visual analog scale (VAS) scores were used to analyze the clinical efficacy.

Results

After treatment, the OPG content in the observation group was higher with statistical significance compared with that before treatment in the observation group and after the treatment in the EA group, respectively (both P<0.05); the content of IL-1β, ODI and VAS scores were lower than those before treatment in the observation group and after treatment in the EA group with statistical significances (all P<0.05).

Conclusion

The combination of EA and hydro-acupuncture with sinomenine hydrochloride at Jiaji (EX-B 2) points is effective for low back pain caused by compression fractures in the elderly, and is superior to EA at Jiaji (EX-B 2) points alone.

     

康复训练配合中药口服治疗脑卒中后肢体痉挛疗效观察

目的 观察康复训练配合中药口服对脑卒中后肢体痉挛疗效的影响.方法 将患者随机分为两组,均予常规综合康复训练,治疗组在常规康复训练的基础上配合中药口服;治疗1～2疗程后,采用改良Ashworth量表和Barthel指数对两组治疗前后肢体痉挛状态及日常生活活动能力进行评分.结果 两组治疗后上、下肢痉挛评分及Barthel指数评分较治疗前有明显改善,而治疗组改善优于对照组.结论 康复训练配合中药口服能明显改善脑卒中患者肢体痉挛状态,提高患者日常生活活动能力.