“心气虚”患者左心室功能的研究

“心气”是指“心藏血脉之气”,《内经》所云“心主身之血脉”,“经脉流行不止,环周不休”之正常血液循环,全赖心气为动力。《医学真传》说:“人之一身皆气血之所循行……血非气不运。”《诸病源候论》谓“……心主血脉,而气血通荣脏腑,遍循经络……心统领诸脏,其劳伤不足,则令惊悸、恍惚,是心气虚也。”说明心气不足则推动血液运行功能减     

益气活血法治疗冠心病心绞痛的临床及实验研究

本研究采用单盲法,在同一患者自身前后对照气血注射液及葡萄糖液对心绞痛的疗效。结果说明心绞痛症状及心电图的疗效,气血注射液均十分明显优于葡萄糖液,并经次极量活动平板运动试验的客观验证,气血注射液确可提高冠心病患者运动耐受量,而葡萄糖液则无此作用,证明气血注射液治疗心绞痛的疗效是肯定的。该药并明显改善左心功能及心排量,改善血液的流变性及微循环,增加心肌营养血流量,对心肌细胞膜钠-钾 ATP 酶的活性有一定的抑制作用。     

高血压病患者超声心动图与中医辨证分型的关系

高血压病是危害人们健康的常见病,是以动脉血压增高为主要临床表现,长期高血压可引起血管、心、脑、肾等器官的病变。我们应用超声心动图多普勒技术,按1979年我国修订的高血压临床分期标准,观察31例Ⅰ、Ⅱ期高血压病患者。其Ⅰ、Ⅱ期患者的心内结构及左心功能的变化与中医辨证分型有一定的关系。1 一般资料:高血压病Ⅰ期患者9例,男性4例,女性5例;年龄最小37岁,最大76岁,平均年龄52岁;病程最短的6～7年,最长的10多年,平均8～9年;临床表     

生脉散对冠心病心绞痛患者左心室功能的影响

冠心病心绞痛患者多有心气虚的临床表现,尤其是急性心肌梗塞患者伴有心衰或休克时,心气虚等表现更为明显。生脉散治疗冠心病已获得较好的疗效,为探讨心气虚的实质以及生脉散的作用机理,我们应用心脏收缩时相(Systolic Time Intervals简称STI)及心尖搏动图为观察方法,选择一组冠心病心绞痛具有心气虚表现的患者,观察生脉散注射液对左心室功能的影响。     

CLINICAL AND EXPERIMENTAL STUDIES OF CORONARY HEART DISEASE TREATED WITH YI-QI HUO-XUE INJECTION

The purpose of the present work was to evaluatethe clinical efficacy and the mechanism of Yi-qiHuo-xue Injection(YHI 益气活血注射液)in treat-ment of coronary heart disease.YHI consists ofGinseng,Astragalus and Angelicae Sinensis.(人参黄芪,当归).The 10% dextrose serves as a pla-cebo.The results were as follows:1.the frequencyand severity of angina episodes were reduced by90.63%;2.the isehemic ST-T in ECG was improvedin 56.25% of eases;3.the tolerance to treadmillexercise was increased from 348,50 to 505.50 M.;4.the left ventricular function was strengthened,PEP/LVET ratio reduced from 0.45 to 0.36,the activityof(Na -K )ATPase in myocardial cell membraneof rats inhibited by 19.2%;5.the blood viscosity anderythrocyte electrophoretic time lowered;6.theadhesion and aggregation of platelet in patients withCHD were inhibited by 27% and 59.4% respectively;7.the plasma TXB_2 level in CHD was reduced from260.28±164.4 to 139.29±57.01 pg/ml;8.the plasma6-keto-PGF_(1α) level in CHD was increased from33.45±22.5 to 57.48±13.1 pg/ml,and in rats from185.77 to 366.33 pg/ml.The differences were allstatistically significant(P<0.05-0.01)in comparisonwith the placebo group.     

“钩薄冲剂”对哮喘患者呼吸道阻力的影响

我们对27例哮喘患者用"钩薄冲剂"(由钩藤、薄荷、马兜铃、紫菀组成)进行了临床即时疗效观察,并对20例患者测定了呼吸道阻力。27例患者中,支气管哮喘或合并支气管炎者15例,慢性喘息型支气管炎12例。6例为急性发作,其余均为慢性迁延期或哮喘慢性连续发作状态。病程6年以下者6例,7～20年者8例,20年以上者13例。     

EFFECT OF SHENG MAI SAN ON LEFT VENTRICULAR PERFORMANCE IN CORONARY HEART DISEASE

The present study aims at ascertaining thenature of Xin Qi Xu (XQX,deficiency of Heart-Qi) and the effect of the drug Sheng Mai San 生脉散(SMS) on heart performance,using systolicand diastolic time intervals as criteria in CHDassociated with XQX patients.The results ascompared with normal subjects showed increa-ses in QA_2,PEP,ICT,IRP,SFP,RFP,a/H%,PEP/LVET and SFP/RFP and a reduction ofLVET,suggesting that the patients have a la-tent cardiac insufficiency possibly relating tothe nature of XQX.The changes in systolic anddiastolic time intervals after intravenous ShengMai San were prolongation of MST and LVET,shortening of PEP and PEP/LVET,and slowingof heart rate.These changes are statisticallysignificant (P<0.05-0.001).The blood pressurewas not significantly changed.These changesand their degree suggest a positive inotropic ac-tion on myocardium and a reduction of myo-cardial oxygen consumption by Sheng Mat San.Its effects compared with Cedilanid-D showedthat the action of both drugs on systolic anddiastolic time intervals was similar.We ten-tatively suggest,therefore,that the inotropicaction of SMS simulates that of digitalis glycosi-des.Further studies are needed to determinewhether SMS affects the heart in the same wayas digitalis glycosides,for current work indica-tes that SMS may have other effects on theheart.     

生脉液对急性心肌梗塞患者左心室功能的影响

生脉液已广泛用于治疗急性心肌梗塞伴休克、心衰的患者,并取得了较好的临床疗效。为了进一步了解生脉液对急性心肌梗塞左心功能的效应,并初步探索其作用原理,本文应用心脏收缩时相(SystolicTime Intervals;以下简称 STI)和心尖搏动图观察了生脉液对急性心肌梗塞患者左心室功能的影响,报告如下:     

多普勒测试党参口服液对冠心病心功能改善的研究

多普勒测试党参口服液对冠心病心功能改善的研究赵悦如（北京中医药大学东直门医院功能科北京１００７００）关键词：多普勒，心功能，党参口服液冠心病属中医胸痹证范畴，近年来在中药治疗冠心病的研究中，取得可喜进展。笔者应用超声脉冲多普勒左心功能测定的方法观察党...