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1.
诌议2004年美国SCI-Expanded收录中国大陆科技期刊 总被引：1，自引：0，他引：1
报道了2004年SCIE收录中国大陆科技期刊的情况，分析了期刊及论文被SCIE收录的意义，最后，就如何正确使用和看待SCI评价指标谈了作者的看法。 相似文献
2.
大鼠脊髓损伤后NGF及其受体TrkA在运动神经元及神经胶质细胞表达的变化 总被引：5，自引：0，他引：5
为探讨脊髓损伤后运动神经元及神经胶质细胞内神经生长因子(NGF)及其高亲和力受体(TrkA)表达的变化,用改良Allen重击法损伤SCI组动物T12脊髓,按伤后存活时间再将动物分为脊髓损1 d组、2 d组和5 d组。各组动物的脊髓切片经ABC法免疫组织化学染色,用光镜观察TrkA及NGF在脊髓前角运动神经元表达的变化和胶质纤维酸性蛋白(GFAP)及NGF免疫反应阳性胶质细胞的反应性增生程度,并进行图像分析。结果显示:脊髓损伤后前角运动神经元TrkA及NGF的表达随脊髓损伤后动物存活时间的延长逐渐上调;脊髓白质和灰质内尤其是皮质脊髓束内GFAP及NGF阳性胶质细胞明显增生;与此同时,室管膜细胞内亦可见明显的NGF免疫反应产物。上述结果表明,脊髓损伤可刺激脊髓前角运动神经元表达TrkA及NGF,通过自分泌维持受损神经元的存活;损伤部位反应性增生的胶质细胞亦可产生NGF,通过旁分泌作用于脊髓前角运动神经元或皮质脊髓束的轴突末梢,以维持运动神经元的存活及促进皮质脊髓束的再生;适时补充外源性神经营养素或改变损伤局部的微环境将有利于受损脊髓的修复和再生。 相似文献
3.
【目的】 了解目前中国SCI期刊总体表现以及与国外出版平台的合作情况,为中国英文科技期刊平台建设,以及国外出版商的挑选提供参考。【方法】 以同时被SCI和《中科院期刊分区表》收录的中国科技期刊为数据源,对比分析相关学科期刊,以及不同出版平台的SCI期刊的表现。【结果】 总体上,中国大部分SCI期刊的影响因子及发文量较低,其中,与国际出版平台合作的SCI期刊表现相对更好,国内期刊平台建设相对较弱,不少出版社开始由“借船出海”转向“造船出海”,着力打造自己的国际出版平台。【结论】 中国SCI期刊实力总体偏弱且学科覆盖度不高,借船出海仍是目前提升中国科技期刊影响力较为有效的方式,而打造我国自己的国际出版平台的需求日益凸显。 相似文献
4.
《中国现代医生》2020,58(25):11-14
目的 评价低频电刺激联合膀胱功能训练治疗脊髓损伤(SCI)诱发的神经源性膀胱(NB)的效果。方法 选取2017年5月～2019年2月我院骨科门诊就诊的SCI诱发NB患者90例,随机分为观察组与单纯组,每组各45例。观察组予以低频电刺激联合膀胱功能训练治疗,单纯组予以单纯的膀胱功能训练,两组均治疗6周。评估两组治疗前后排尿情况及尿动力学指标的变化,并比较其临床疗效。结果 治疗6周后,两组日均单次排尿量和日单次最大排尿量较治疗前明显增加,日均排尿次数较治疗前明显下降(P0.05或P0.01),且观察组变化幅度较单纯组更显著(P0.05);两组膀胱内压力和Qmax较治疗前明显上升,RU较治疗前明显下降(P0.05或P0.01),且观察组变化幅度较单纯组更显著(P0.05);同时观察组临床总有效率(95.56%)明显高于单纯组(82.22%)(χ2=4.053,P0.05)。结论 低频电刺激联合膀胱功能训练用于治疗SCI诱发NB患者的效果确切,能更明显改善患者的排尿情况及尿动力学状态。 相似文献
5.
目的 统计分析目前国内学者在SCI期刊发表的眼科领域系统评价和Meta分析论文情况，为今后发表此类研究提供参考。设计 描述性研究。研究对象 在PubMed、EMBASE及Cochrane library三大数据库中收录的所有眼科领域的系统评价和Meta分析论文。方法 系统检索PubMed、EMBASE及Cochrane library三大数据库。检索时，限定研究对象为人类，语言为英语，检索时间截止到2017年1月30日。通过阅读标题、摘要及全文，排除重复及不相关研究，将最终符合条件的研究按作者来源、发表年限、疾病类型等进行归类分析。主要指标 作者来源、发表年限、疾病类型。 结果 三大数据库共检索到10 551条题录（PubMed 4214，EMBASE 6155，Cochrane library 182）。排除重复及不相关研究后，最终符合条件的系统评价和Meta分析442篇。此类研究最早发表于2004年，按年发表量排名，前三名分别是：2015（100篇，22.62%）、2014（91篇，20.59%）、2016（90篇，20.36%）。共有来自52个城市的作者参与发表过此类研究，前三名城市分别是：上海（95篇，21.49%）、北京（45篇，10.18%）、广州（38篇，8.60%）。共有126种杂志发表此类研究，前三名杂志分别是：PLoS One (79篇，17.87%)、Molecular Vision（16篇，3.62%）、BMC Ophthalmology（15篇，3.39%）。研究内容以视网膜疾病最多，前三名疾病分别是：视网膜疾病（168篇，38.01%）、青光眼（95篇，21.49%）、屈光手术（47篇，10.63%）。定性系统评价17篇（3.85%），Meta分析425篇（96.15%）。在Meta分析中干预性研究177篇，观察性研究248篇，后者以基因相关研究（137篇）、危险因素（84篇）为主。结论 国内学者在眼科领域系统评价发表量逐年增多，作者主要集中于国内大城市，尤其是上海和北京，研究热点主要是视网膜疾病、青光眼，非干预性研究发表量已超越干预性研究，其中以基因相关研究及危险因素研究为主。 相似文献
6.
Marcalee Alexander Khurram Bashir Craig Alexander Lesley Marson Raymond Rosen 《Archives of physical medicine and rehabilitation》2018,99(2):299-305
Objective
To examine the safety and efficacy of using a clitoral vacuum suction device (CVSD) versus vibratory stimulation (V) to treat orgasmic dysfunction in women with multiple sclerosis (MS) or spinal cord injury (SCI).Design
Randomized clinical trial.Setting
Two academic medical centers.Participants
Women (N=31) including 20 with MS and 11 with SCI.Intervention
A 12-week trial of the use of a CVSD versus V.Main Outcome Measures
Female Sexual Function Inventory (FSFI) and Female Sexual Distress Scale (FSDS).Results
Twenty-three women (18 MS, 5 SCI) completed the study including 13 of 16 randomized to CVSD and 10 of 15 randomized to V. There was a statistically significant increase in total FSFI score (P=.011), desire (P=.009), arousal (P=.009), lubrication (P=.008), orgasm (P=.012), and satisfaction (P=.049), and a significant decrease in distress as measured by FSDS (P=.020) in subjects using the CVSD. In subjects who used V, there was a statistically significant increase in the orgasm subscale of the FSFI (P=.028). Subjects using the CVSD maintained improvements 4 weeks after treatment.Conclusions
CVSD is safe and overall efficacious to treat female neurogenic sexual dysfunction related to MS and SCI. V is also safe and efficacious for female neurogenic orgasmic dysfunction; however, results were limited to the active treatment period. Because of ease of access and cost, clinicians can consider use of V for women with MS or SCI with orgasmic dysfunction. CVSD is recommended for women with multiple sexual dysfunctions or for whom V is ineffective. 相似文献7.
Sarah A. Morrison Douglas Lorenz Carol P. Eskay Gail F. Forrest D. Michele Basso 《Archives of physical medicine and rehabilitation》2018,99(3):555-562
Objective
To determine the impact of long-term, body weight–supported locomotor training after chronic, incomplete spinal cord injury (SCI), and to estimate the health care costs related to lost recovery potential and preventable secondary complications that may have occurred because of visit limits imposed by insurers.Design
Prospective observational cohort with longitudinal follow-up.Setting
Eight outpatient rehabilitation centers that participate in the Christopher & Dana Reeve Foundation NeuroRecovery Network (NRN).Participants
Individuals with motor incomplete chronic SCI (American Spinal Injury Association Impairment Scale C or D; N=69; 0.1–45y after SCI) who completed at least 120 NRN physical therapy sessions.Interventions
Manually assisted locomotor training (LT) in a body weight–supported treadmill environment, overground standing and stepping activities, and community integration tasks.Main Outcome Measures
International Standards for Neurological Classification of Spinal Cord Injury motor and sensory scores, orthostatic hypotension, bowel/bladder/sexual function, Spinal Cord Injury Functional Ambulation Inventory (SCI-FAI), Berg Balance Scale, Modified Functional Reach, 10-m walk test, and 6-minute walk test. Longitudinal outcome measure collection occurred every 20 treatments and at 6- to 12-month follow-up after discharge from therapy.Results
Significant improvement occurred for upper and lower motor strength, functional activities, psychological arousal, sensation of bowel movement, and SCI-FAI community ambulation. Extended training enabled minimal detectable changes at 60, 80, 100, and 120 sessions. After detectable change occurred, it was sustained through 120 sessions and continued 6 to 12 months after treatment.Conclusions
Delivering at least 120 sessions of LT improves recovery from incomplete chronic SCI. Because walking reduces rehospitalization, LT delivered beyond the average 20-session insurance limit can reduce rehospitalizations and long-term health costs. 相似文献8.
Chelsea A. Harris John-Michael Muller Melissa J. Shauver Kevin C. Chung 《Archives of physical medicine and rehabilitation》2018,99(3):459-467.e1
Objectives
To (1) characterize patients' medical experiences from initial injury until they become candidates for upper extremity reconstruction (UER); and (2) identify points in this medical context that may be most amenable to interventions designed to increase UER utilization.Design
A qualitative cross-sectional study using grounded theory methodology and constant comparative analysis of data collected through semistructured individual interviews.Setting
Community.Participants
A sample of individuals with C4 to C8 cervical spinal injuries (N=19) who sustained injuries at least 1 year before interview. Nine patients had undergone reconstruction, and 10 had not. The study sample was predominantly male (79%) and white (89%), and American Spinal Injury Association grades A through D were represented (A, 42%; B, 32%; C, 16%; D, 10%).Interventions
Not applicable.Main Outcome Measures
Participants' self-report of their medical experiences from the time of injury through the early recovery period.Results
We identified 3 domains that formed patients' medical context before UER candidacy: (1) their ability to achieve and maintain health; (2) their relationship with health care providers; and (3) their expectations regarding clinicians' tetraplegia-specific expertise. Trust emerged as a major theme driving potential intervention targets. Patients transferred to referral centers had higher trust in tertiary providers relative to local physicians. In the outpatient setting, patients' trust correlated with the tetraplegia-specific expertise level they perceived the specialty to have (high for physical medicine and rehabilitation, intermediate for urology, low for primary care).Conclusions
In appropriate candidates, UER produces substantial functional gains, but reconstruction remains underused in the tetraplegic population. By analyzing how patients achieve health and build trust in early recovery/injury, our study provides strategies to improve UER access. We propose that interventions targeting highly trusted points of care (transfer hospitals) and avoiding low-trust points (primary care physicians, home health) will be most effective. Urology may represent a novel entry point for UER interventions. 相似文献9.
Jason S. Au Arjun Sithamparapillai Katharine D. Currie Andrei V. Krassioukov Maureen J. MacDonald Audrey L. Hicks 《Archives of physical medicine and rehabilitation》2018,99(10):1991-1997
Objective
To assess the feasibility of measuring ventilatory threshold (VT) in higher-level motor-complete spinal cord injury (SCI) using 4 different analysis methods based on noninvasive gas exchange.Design
Observational.Setting
Laboratory testing.Participants
Individuals with C4-T6 motor-complete SCI (16 paraplegia, 22 tetraplegia; American Spinal Injury Association Impairment Scale A/B; 42±10 years old).Interventions
Not applicable.Main Outcome
VT from a graded arm cycling test to volitional exhaustion using 4 methods: ventilatory equivalents, excess CO2, V-slope, and combined method.Results
VT could be identified in all individuals with paraplegia, but in only 68% of individuals with tetraplegia. Individuals without observable VT completed the graded exercise test with lower ventilatory rate, peak power output, and peak oxygen consumption (Vo2peak) (all P<.05), compared to those with a detectable VT. Bland-Altman plots indicate minimal bias between methods (range: 0.01-0.03 L/min), with 95% limits of agreement of the difference within 0.25 L/min. Absolute o2 at VT with individual methods were all correlated to peak power output (r>0.74; P<.01) and Vo2peak (r>0.91; P<.01), with negligible differences between methods.Conclusions
The assessment of VT is a feasible alternative to peak exercise testing for aerobic fitness in individuals with higher-level, motor-complete SCI, although care should be taken when interpreting VT in individuals with tetraplegia who have lower cardiorespiratory fitness and lower peak power outputs. 相似文献10.
Hui-Fen Mao Hsing-Po Huang Tung-Wu Lu Ting-Ming Wang Cheng-Hua Wu Jwu-Sheng Hu 《Archives of physical medicine and rehabilitation》2018,99(10):1982-1990