全文获取类型
收费全文 | 17951篇 |
免费 | 2246篇 |
国内免费 | 530篇 |
专业分类
耳鼻咽喉 | 13篇 |
儿科学 | 313篇 |
妇产科学 | 53篇 |
基础医学 | 1012篇 |
口腔科学 | 56篇 |
临床医学 | 2062篇 |
内科学 | 2628篇 |
皮肤病学 | 170篇 |
神经病学 | 431篇 |
特种医学 | 455篇 |
外科学 | 2126篇 |
综合类 | 3839篇 |
现状与发展 | 3篇 |
一般理论 | 1篇 |
预防医学 | 934篇 |
眼科学 | 2757篇 |
药学 | 1753篇 |
11篇 | |
中国医学 | 2046篇 |
肿瘤学 | 64篇 |
出版年
2024年 | 53篇 |
2023年 | 488篇 |
2022年 | 660篇 |
2021年 | 929篇 |
2020年 | 942篇 |
2019年 | 751篇 |
2018年 | 784篇 |
2017年 | 884篇 |
2016年 | 900篇 |
2015年 | 887篇 |
2014年 | 1407篇 |
2013年 | 1395篇 |
2012年 | 1296篇 |
2011年 | 1406篇 |
2010年 | 1014篇 |
2009年 | 833篇 |
2008年 | 777篇 |
2007年 | 757篇 |
2006年 | 648篇 |
2005年 | 616篇 |
2004年 | 471篇 |
2003年 | 377篇 |
2002年 | 328篇 |
2001年 | 295篇 |
2000年 | 213篇 |
1999年 | 188篇 |
1998年 | 146篇 |
1997年 | 151篇 |
1996年 | 101篇 |
1995年 | 98篇 |
1994年 | 87篇 |
1993年 | 74篇 |
1992年 | 76篇 |
1991年 | 49篇 |
1990年 | 40篇 |
1989年 | 63篇 |
1988年 | 51篇 |
1987年 | 50篇 |
1986年 | 39篇 |
1985年 | 66篇 |
1984年 | 49篇 |
1983年 | 34篇 |
1982年 | 57篇 |
1981年 | 40篇 |
1980年 | 36篇 |
1979年 | 17篇 |
1978年 | 17篇 |
1977年 | 13篇 |
1976年 | 12篇 |
1973年 | 12篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
Diabetic foot ulcer is a devastating complication of diabetes mellitus and significant cause of mortality and morbidity all over the world and can be complex and costly. The development of foot ulcer in a diabetic patient has been estimated to be 19%-34% through their lifetime. The pathophysiology of diabetic foot ulcer consist of neuropathy, trauma and, in many patients, additional peripheral arterial disease. In particular, diabetic neuropathy leads to foot deformity, callus formation, and insensitivity to trauma or pressure. The standard algorithms in diabetic foot ulcer management include assessing the ulcer grade classification, surgical debridement, dressing to facilitate wound healing, off-loading, vascular assessment (status and presence of a chance for interventional vascular correction), and infection and glycemic control. Although especially surgical procedures are sometimes inevitable, they are poor predictive factors for the prognosis of diabetic foot ulcer. Different novel treatment modalities such as nonsurgical debridement agents, oxygen therapies, and negative pressure wound therapy, topical drugs, cellular bioproducts, human growth factors, energy-based therapies, and systematic therapies have been available for patients with diabetic foot ulcer. However, it is uncertain whether they are effective in terms of promoting wound healing related with a limited number of randomized controlled trials. This review aims at evaluating diabetic foot ulcer with regard to all aspects. We will also focus on conventional and novel adjunctive therapy in diabetic foot management. 相似文献
4.
5.
6.
BackgroundPassive and hybrid passive ankle foot orthoses (AFOs) are often prescribed in post stroke drop foot; however, the effects of these AFOs on balance related parameters in these patients seem unclear. Accordingly, the aim of current study was to evaluate the role of the newly designed hybrid passive and Posterior Leaf Spring (PLS) AFOs on balance related parameters including: self-reported balance confidence (ABC), Timed Up and Go Test (TUG) and Berg Balance Scale (BBS) in post stroke drop foot patients.MethodsFifteen post stroke drop foot patients were recruited in current study. Then, ABC, TUG and BBS were assessed with newly designed AFO and PLS AFO.ResultsThe results of this study were shown a significant improvement in ABC, TUG and BBS scores with the newly designed AFO than PLS AFO (p < 0.05).ConclusionThis study suggested that the newly designed AFO was improved the balance related parameters than PLS AFO. 相似文献
7.
8.
Hisham F. Bahmad Robert Poppiti John Alexis 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2021,15(2):487-491
Background and aimsDiabetes mellitus (DM) is a chronic metabolic disease associated with long-term multisystem complications, among which nonhealing diabetic foot ulcers (DFUs) are recognized as major cause of morbidity and mortality. Treating DFUs with surgical procedures such as synthetic or biological skin grafts or skin substitutes has several limitations, where none of the currently available skin substitutes is ideal.MethodsOVID/Medline and PubMed databases were searched using the Medical Subject Heading (MeSH) or Title/Abstract words (“diabetic foot ulcers”, “skin substitutes”, and “nanofibers”), to identify published research studies on DFUs and nanofibers.ResultsElectrospinning nanotechnology is being used in the biomedical field to produce polymeric nanofibers impregnated with drugs for wound healing, burns and diabetic ulcers. Those nanofibers also enable seeding of cells into them and culturing them in vitro to synthesize tissue-like structures. Knowing the advantages of generating patient-specific induced pluripotent stem cells (iPSCs) and organoids in three-dimension (3D), including skin organoids, it is worth mingling these technologies to develop tissue-engineered biological skin substitutes.ConclusionNanofiber-skin substitutes hold promise for treatment of patients suffering from DFUs and inspire novel strategies that could be applied to other organ systems as well, introducing a new era of “regenerative and personalized medicine”. 相似文献
9.
Sarah J. Schrauben Haochang Shou Xiaoming Zhang Amanda Hyre Anderson Joseph V. Bonventre Jing Chen Steven Coca Susan L. Furth Jason H. Greenberg Orlando M. Gutierrez Joachim H. Ix James P. Lash Chirag R. Parikh Casey M. Rebholz Venkata Sabbisetti Mark J. Sarnak Michael G. Shlipak Sushrut S. Waikar Paul L. Kimmel Ramachandran S. Vasan Harold I. Feldman Jeffrey R. Schelling 《Journal of the American Society of Nephrology : JASN》2021,32(1):115
10.