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1.
目的:通过对颈椎病患者上下终板弧形高度、椎间隙高度与椎间隙后骨赘的影像学测量,研究其相关性及其临床应用价值。方法:收集2017年9月至2018年9月颈椎病手术108例患者的临床资料,男48例,年龄30~72岁,平均52岁,女60例,年龄37~79岁,平均54岁。其中C2,3 6例,C3,4 15例,C4,5 32例,C5,6 42例,C6,7 13例。术前及术后摄颈椎X线片,利用PACS(Picture Archiving and Communication Systems)调阅影像,测量椎间隙的下上终板弧形高度(L1,L2),椎间隙高度(L3)及后方骨赘的宽度(L4)。利用Spearman分析它们之间的相关性。结果:L1与L4对比(r=-0.34,P<0.05),L3与L4对比(r=-0.36,P<0.05),存在负相关。L1与L3对比(r=0.38,P<0.05),L2与L3对比(r=0.48,P<0.05),存在正相关。L1与L2对比(P>0.05),L2与L4对比(P>0.05),差异无统计学意义。结论:下终板弧形高度与椎间隙后缘骨赘宽度呈负相关,通过其测量可明确颈椎退变程度,对颈椎病的早期防治有指导意义。 相似文献
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3.
《Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society》2021,29(12):1691-1700
4.
《Foot and Ankle Surgery》2021,27(8):928-933
BackgroundThe efficacy of the powered rasp, a new reciprocating motion device for arthroscopic resection of osteophytes, has not been verified. The aim of this study was to compare the intraoperative efficacy of the powered rasp in arthroscopic resection of anterior ankle osteophytes to that of the conventional burr.MethodsA total of 49 consecutive patients who underwent arthroscopic resection of anterior ankle osteophytes (26 patients with the conventional burr and 23 patients with the powered rasp) were retrospectively reviewed. The preoperative volume of each osteophyte was measured using computerized tomography scan and three-dimensional software. The resection time was measured by review of the individual arthroscopy video, and the estimated resection rate was calculated as the volume of osteophytes/resection time.ResultsThe preoperative volume of osteophytes was not different between the two groups (847.8 ± 685.3 mm3 in the conventional burr and 913.3 ± 605.8 mm3 in the powered rasp, p = 0.726). The resection time was 442.4 ± 216.6 s (seconds) in the conventional burr and 386.4 ± 186.3 s in the powered rasp, and the estimated resection rate was 1.8 ± 1.0 mm3/s with the conventional burr and 2.4 ± 1.3 mm3/s with the powered rasp. These measurements were not significantly different between the two groups (p = 0.340 and 0.083, respectively).ConclusionThe intraoperative efficacy of the powered rasp did not show superiority to that of the conventional burr in arthroscopic resection of anterior ankle osteophytes.Level of evidenceLevel III, retrospective comparative study. 相似文献
5.
Seiya Jingushi Jun-ichi Shida Yukihide Iwamoto Takayuki Kinoshita Yoshiyuki Hiyama Makoto Tamura 《Connective tissue research》2013,54(4):242-248
Fibroblast growth factor-2 (FGF-2) has the potential to regenerate damaged articular cartilage tissue due to its exerting anabolic effects on chondrocytes. However, FGF-2 is involved in pathogenesis of rheumatoid arthritis, where the joint is destructed. The study aims at clarifying the effects of FGF-2 on joints. When radiolabeled FGF-2 was injected into knee joints of C57Bl/10 mice, a transient binding was observed in the superficial and intermediate zones of the articular cartilage as well as in the synovium and perichondrium. An FGF-2 injection (5 μg) caused synovial hyperplasia adjacent to the articular cartilage on day 7, cartilage formation adjacent to the articular cartilage on day 14, and osteophyte on day 21. The intensity of safranin-O staining of the articular cartilage increased on day 14. These changes were dose-dependent. No destructive changes in the joints were observed. In a joint, transient exposure of FGF-2 caused proliferative changes, but not destructive changes. 相似文献
6.
《Joint, bone, spine : revue du rhumatisme》2022,89(4):105353
ObjectivesTo illustrate the microstructural and histomorphological characteristics of osteophytes in the human knee osteoarthritis (OA).MethodsTibial plateau specimens, including osteophytes and subchondral trabecular bone (STB) from weight-bearing and non-weight-bearing regions, were obtained from 81 patients with OA after total knee arthroplasty surgery. All the patients had varus deformity of the knee. Micro-CT was applied to evaluate the microstructure characteristics of the tibial plateau, which was segmented into 6 regions of interest (ROIs). After micro-CT scanning, decalcified and undecalcified bone histology were performed to assess histological features and bone remodeling status in these different ROIs.ResultsIn both medial and lateral plateaus, osteophytes exhibited a less sclerotic microstructure and higher bone remodeling level compared with STB from weight-bearing and non-weight-bearing regions. Moreover, the medial osteophyte tended to have a more sclerotic microarchitecture and a relatively low level of bone metabolism than its lateral counterpart. Osteophyte, which consists of mesenchymal connective tissue cap, cartilage and mineralized bone tissue, demonstrated evident chondrocyte hypertrophy and endochondral ossification in the cartilage-to-bone interface. Compared with the non-weight-bearing region, the weight-bearing region showed more severely deteriorated cartilage, and more sclerotic subchondral bone with high remodeling status.ConclusionOsteophytes exhibited a sparse microstructure and high bone remodeling level in knee OA, but demonstrating region-dependent variations. In addition, the microstructure, bone metabolism status and pathological alterations of osteochondral complex were distinct between weight-bearing and non-weight-bearing regions in the tibial plateau. Biomechanical stress might play a pivotal role in osteophyte formation and deterioration of osteochondral complex. 相似文献
7.
Alpaslan Öztürk Yüksel Özkan Recai M. Özdemir Nazan Yalçın Semra Akgöz Vedat Saraç Serkan Aykut 《European spine journal》2008,17(1):136-141
Heavy physical work and activity lead to degenerative changes, especially in the lumbar spine. We aimed to find out the occurence
of radiographic changes (vertebral osteophytes, heights of lumbar dicsc, concavity index) and abnormalities of the lumbar
spine in former professional football (association football or soccer) players according to their specialization (goalkeeper,
defender, midfielder, forward) in their past professional sport life.
We included 70 male former professional football players and 59 men as the control group. The football players group consisted
of 15 defenders (21%), 29 midfielders (41%), 18 forwards (26%) and 8 goalkeepers (12%). Their mean professional football life
was 11.04 years and the mean time period after their retirement was 13.87 years. Radiographs of both groups were taken to
measure the disc height, concavity index and to determine osteophytes and abnormalities of the lumbar spine. FFbH-R score
was assessed for daily activities.
The mean FFbH-R score of football players was lower than that of the control group (P = 0.005). The total number of osteophytes in the player group was higher than in the control group (P = 0.001). The mean disc height of L1–L2 in football players was higher than in the control group (P = 0.045). The mean disc height of T12–L1 in goalkeepers was higher than in forward players (P = 0.019). The mean concavity index of L1 in forward players was lower than in defenders (P = 0.018). The mean disc heights of T12–L1 and L2–L3 were both higher in players whose professional sport life was >10 years
than in players with ≤10 years (P = 0.018, P = 0.016). The mean disc height of L5–S1 was higher in players who had continued sport activity after retirement (P = 0.025). No statistically significant result was obtained with the rest of the variables.
Playing football is heavy work. The decreased height of lumbar discs and the lower value of concavity index of forward players
are because the lumbar spine of forward players is loaded more than in the rest of the players.
Presented in part orally at Eurospine 2006, İstanbul, Turkey, 25–28 October 2006. Presented in part as poster at XXXVI Scientific
Congress of Polish Orthopaedic and Traumatology Society, Katowice, Polland, 28–30 September 2006. 相似文献
8.
Kuan Wang MD Chenghua Jiang PhD Lejun Wang PhD Huihao Wang MD Wenxin Niu PhD 《The spine journal》2018,18(12):2288-2296
BACKGROUND CONTEXT
Anterior vertebral body osteophytes are common with degeneration but their biomechanical influence on the whole lumbar spine remains unclear.PURPOSE
To investigate the biomechanical influence of anterior vertebral body osteophytes on the whole lumbar spine.STUDY DESIGN/SETTING
This is a study using finite element analysis.OUTCOME MEASURES
Intersegmental rotation, maximum Mises stress, and intradiscal pressure on the intervertebral discs of different lumbar levels were calculated.METHODS
A finite element model of an intact lumbar spine was constructed and validated against in vitro studies. The modified models, which had different degrees of anterior vertebral body osteophyte formation (OF) in combination with disc space narrowing, were applied with physiological loadings.RESULTS
The lumbar levels with various degrees of OF altered the kinematics of these levels, which also affected the whole lumbar spine. In flexion and lateral bending, the segment that was one level inferior to the vertebra with OF showed a trend towards increased range of motion. On the intervertebral discs that were one level inferior to the OF level, a trend towards increase in the maximum von Mises stress was found on the annulus.CONCLUSIONS
Segments adjacent to levels with anterior vertebral body osteophytes showed increased intersegmental rotation and maximum stress. Further clinical observation should be performed to verify the results in vivo. 相似文献9.
Keisuke Higuchi Masatoshi Chiba Takemitsu Kondo Seishi Echigo 《Oral Science International》2013,10(1):33-39
PurposeDecreased signal intensity on T1- or proton-density weighted magnetic resonance imaging (MRI) and increased signal intensity on T2-weighted MRI in the bone marrow space are thought to reflect bone marrow edema (BME). The purpose of this study was to determine whether condyle BME is associated with condyle bone changes.MethodsThe subjects were 57 patients [65 temporomandibular joints (TMJs)] with TMJ disorders showing condyle BME on initial MRI. Condyle bone changes were compared between TMJs that showed a persistent BME pattern (group P, 43 TMJs in 40 patients) and those that showed normal bone marrow signals, indicating disappearance of BME (group D, 21 TMJs in 22 patients) on follow-up MRI.Results(1) In TMJs with a condyle with a normal shape on initial MRI, condyle bone changes were present in 53.9% of TMJs in group P in follow-up MRI, whereas the normally shaped condyle remained in all TMJs in group D. (2) In TMJs with condyle erosion on initial MRI, condyle erosion was also present in 35.7% of TMJs in group P in follow-up MRI, but had disappeared in all TMJs in group D. (3) In TMJs with condyle osteophytes on initial MRI, erosion was present in 22.2% of TMJs in group P, whereas osteophytes remained in all TMJs in group D.ConclusionsThe longitudinal study showed that condyle BME is associated with condyle bone changes and may cause condyle erosion. 相似文献
10.
目的通过对膝骨关节炎患者正位x线片的测量,探讨膝骨关节炎患者关节间隙比值与骨赘数量及大小在正位X线片表现上的相关性。方法收集门诊86例(89膝)膝骨关节炎患者的正位x线片,年龄65~85岁;根据关节间隙比值将其分为4组,并统计骨赘数量及测量骨赘大小。结果关节间隙比值正常组膝骨关节炎患者骨赘增生数量及总骨赘大小与异常组各组相比均无相关性(P〉0.05)。结论膝骨关节炎患者关节间隙比值与骨赘数量及大小在正位X线片表现上无相关眭。 相似文献