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排序方式: 共有812条查询结果,搜索用时 15 毫秒
91.
William Pavlis David S Constantinescu Rajan Murgai Spencer Barnhill Brian Black 《World journal of orthopedics》2022,13(9):870-875
BACKGROUNDCalcium pyrophosphate dihydrate deposition disease (CPPD), or pseudogout, is an inflammatory arthritis common among elderly patients, but rarely seen in patients under the age of 40. In the rare cases presented of young patients with CPPD, genetic predisposition or related metabolic conditions were almost always identified.CASE SUMMARYThe authors report the case of a 9-year-old boy with no past medical history who presented with acute knee pain and swelling after a cat scratch injury 5 d prior. Synovial fluid analysis identified calcium pyrophosphate dihydrate crystals. Further MRI analysis identified osteomyelitis and a small soft tissue abscess.CONCLUSIONThis case presents the extremely rare diagnostic finding of calcium pyrophosphate dihydrate crystals in a previously healthy pediatric patient. The presence of osteomyelitis presents a unique insight into the pathogenesis of these crystals in pediatric patients. More research needs to be done on the role of CPPD in pediatric arthritis and joint infection. 相似文献
92.
2012年7月至2015年7月,兰州军区兰州总医院对8例股骨创伤后骨髓炎患者彻底清创后采用锁定钢板非接触技术固定骨折端,钢板置于大腿外侧皮下、股外侧肌的外侧。Ⅰ期切取不带皮质髂骨颗粒状松质骨植在清创后血运良好的骨缺损部位,尽量充满死腔,术后放置引流管。8例均顺利完成手术,手术时间120~150 min,平均(130±10)min;术后使用抗菌药物6周;引流管平均放置时间为8 d左右;患者随访12~48个月,平均(19±7)个月。其中7例术后复查X线摄片显示骨愈合,平均愈合时间为(16±5)周;1例感染复发,再次清创后改行骨搬移术。8例均未发生钢板及螺丝钉断裂、松动及固定失败。 相似文献
93.
Matthew Malone Blaine G. Fritz Karen Vickery Saskia Schwarzer Varun Sharma Nathan Biggs Michael Radzieta Thomas T. Jeffries Hugh G. Dickson Slade O. Jensen Thomas Bjarnsholt 《APMIS : acta pathologica, microbiologica, et immunologica Scandinavica》2019,127(10):660-670
Multiple approaches were employed to detect pathogens from bone margins associated with Diabetic Foot Osteomyelitis (DFO). Intra‐operative bone specimens of 14 consecutive subjects with suspected DFO were collected over a six‐month study period from Liverpool Hospital. Infected bone and a proximal bone margins presumed to be ‘clean/non‐infected’ were collected. Bone material was subjected to conventional culture, DNA sequencing and microscopy. In total, eight of 14 (57%) proximal bone margins had no growth by conventional culture but were identified in all proximal bone specimens by DNA sequencing. Proximal margins had lower median total microbial counts than infected specimens, but these differences were not statistically significant. Pathogens identified by sequencing in infected specimens were identified in proximal margins and the microbiomes were similar (ANOSIM = 0.02, p = 0.59). Using a combination of SEM and/or PNA‐FISH, we visualized the presence of microorganisms in infected bone specimens and their corresponding proximal margins of seven patients (50%) with DFO. We identify that bacteria can still reside in what seems to be proximal ‘clean’ margins. The significance and implications of clinical outcomes requires further analysis from a larger sample size that incorporates differences in surgical and post‐operative approaches, correlating any outcomes back to culture‐sequence findings. 相似文献
94.
Sunita Managutti Anil Managutti Michael Pragasm 《Journal of maxillofacial and oral surgery》2012,11(1):109-114
Osteopetrosis (OP) is a rare congenital disorder (present at birth) in which the bones become over dense. This results from an imbalance between the formation of bone and the resorption of the bone. Thickening of the bones which become abnormally dense due to an inherited defect in bone resorption, the process in which old bone is broken down and removed so that new bone can be added to the skeleton. Osteoclasts are the cells responsible for bone resorption. In osteopetrosis the osteoclasts do not perform normally. This flaw in bone resorption results in bones that are abnormally dense, yet are fragile and easily broken. Osteopetrosis is also known as Albers–Schonberg disease, generalized congenital osteosclerosis, ivory bones, marble bones, osteosclerosis fragilis generalisata. In this article, we have described about the diagnosis and medical and surgical management of osteopetrosis reported case to our hospital. 相似文献
95.
目的 比较Masquelet技术与Ilizarov技术治疗成人胫骨慢性骨髓炎清创后大段骨缺损的早期临床疗效.方法 回顾性分析2011年1月至2015年5月我院收治的45例成人胫骨慢性骨髓炎病人资料,Masquelet技术治疗的27例纳入Masquelet组,男20例,女7例,骨缺损长度为(8.9±2.2)cm;Ilizarov技术治疗的18例纳入Ilizarov组,男12例,女6例,骨缺损长度为(8.3±2.1)cm.收集并比较两组病例的骨愈合时间、完全负重时间、术后并发症情况及末次随访时的Iowa膝关节评分、Iowa踝关节评分、SF-36量表得分.结果 45例病人的随访时间为12~38个月,平均(21.5±6.5)个月.Masquelet组与Ilizarov组的骨愈合时间分别为(20.85±4.31)周、(28.86±6.47)周,完全负重时间分别为(23.17±6.93)周、(32.87±6.79)周,两组间比较,差异均有统计学意义(t=4.944,P<0.0001;t=4.636,P<0.0001);两组末次随访时的Iowa膝、踝关节评分及SF-36量表总得分均较术前明显改善,但两组间比较,差异均无统计学意义(P均>0.05).结论 Masquelet技术与Ilizarov技术均可有效地解决成人胫骨慢性骨髓炎清创后大段骨缺损问题,但Masquelet技术能显著缩短治疗周期,完全负重时间早,是一种简单有效的手术方法. 相似文献
96.
Serhat Uysal Bilgin Arda Meltem I Taşbakan Şevki Çetinkalp Ilgın Y Şimşir Anıl M Öztürk Ayşe Uysal İlgen Ertam 《International wound journal》2017,14(6):1219-1224
There is a variety of diagnostic and therapeutic algorithms for diabetic foot infections (DFIs). Some of them are too difficult to be applied in routine clinical approach. In the routine clinical approach, it is necessary to find new risk factors and end up with a quick and easy assessment of DFIs. In this study, we aimed to evaluate the independent risk factors for osteomyelitis, amputation and major amputation in patients with DFI using standard scoring procedures. We prospectively studied 379 patients with DFI. The variables were analysed using logistic analysis. A total of 126 cases (33·2%) underwent amputation. The odds ratios in the amputation model were 3·09 for osteomyelitis (P < 0·001), 4·90 for arterial stenosis (AS) (P < 0·001), 3·67 for the history of DFI (P = 0·001), 2·47 for ulcer duration >60 days (P = 0·001), 3·10 for ulcer depth > 15 mm (P < 0·001) and 10·28 for fungal DFI (P = 0·015). In this study, the unusual result of well‐known literature was fungal DFI as an independent risk factor for amputation in patients with DFI. 相似文献
97.
中西医结合治疗创伤性骨髓炎合并骨缺损 总被引:8,自引:1,他引:8
目的 研究应用中西医结合方法治疗创伤性骨髓炎合并骨缺损的疗效。方法 对132例创伤性骨髓炎合并骨缺损的患者根据创面细菌培养和药敏试验结果,分别选用有效中药于自控中药湿热熬治疗机上恒温冲洗创面2~4周,配合敏感抗菌素的应用,行病灶彻底清除和复合组织移植Ⅰ期治疗。结果 132例中2例手术失败,126例获得1~6年随访,121例治愈,2例骨髓炎复发,3例骨不愈合,结论 在中西医结合控制感染基础上,应用显 相似文献
98.
99.
《The Foot》2021
BackgroundThe bioactive glass (BAG) is a promising solution for the reconstruction of bone defects and the eradication of infection in patients with osteomyelitis, however references to the treatment of diabetic foot osteomyelitis are scarce in the literature.MethodsOur experience in patients with diabetic foot osteomyelitis, who required surgical debridement and void filling, in which we use bioactive glass (n = 6), was evaluated. During a minimum follow-up of 24 months, the presence of persistent infection and healing rate, post-surgical complications, surgical reinterventions, degree of osseointegration and BAG-related side effects was analyzed.ResultsAt the end of the follow-up, none of the patients showed signs of persistent infection and the healing rate was 66.6% (4/6).Postoperative complications were noted in 3 patients and two of the them required new surgical intervention, both due to skin coverage or vascular complications.A complete osseointegration in the 66.6% of the patients and no cases of local adverse effects were recorded.ConclusionsThe bioactive glass can be a useful tool in the treatment of certain cases of diabetic foot osteomyelitis, provided that a multidisciplinary approach and strict patient selection is in place.Level of evidenceIV. 相似文献
100.