超声血管造影在射频治疗子宫良性肿瘤中的应用初探

目的研究超声血管造影在射频治疗子宫良性肿瘤中的应用价值。方法选择本院经阴道射频治疗子宫良性肿瘤患者144例,除14例术后未获随访外,余130例术前及术后6个月B超检查观察瘤体变化情况;同时对其中78例作治疗前、治疗后即时,以及术后第1、3、6个月作子宫超声血管造影,评价病灶部位血流变化。对造影组与未造影组作射频治疗疗效比较分析。结果子宫良l生肿瘤治疗前后超声血管造影表像更为直观。治疗后1个月开始超声血管造影疗效评价与6个月常规B超检查疗效一致。同时,表明造影组治疗有效率明显高于未造影组（P〈0．05）。结论超声血管造影应用于射频治疗子宫良性肿瘤,操作简便,早期能较准确地判断肿瘤的预后,可显著提高射频治疗疗效。     

基于VTK的数字肠道可视化和位置映射研究

目的建立表面重建三维数字肠道和肠道位置映射模型。方法利用第2套中国虚拟人数据集的彩色断面图像手动分割出肠道,再在VC 环境下借助可视化工具包VTK进行表面重建和肠道相对位置映射功能实现。结果系统的实现功能包括:①虚拟人体肠道的面绘制,其中实体颜色、透明度、背景颜色、网格删减系数、表面平滑次数和光线效果等参数可以设定,以达到不同的面绘制效果。②具有旋转、平移、缩放和正交视图等方便的交互式操作。③从三维空间坐标到肠道相对位置的映射。结论此系统可以独立运行,具有较强的可移植性和扩展性,可应用于肠道内的定位,教学和科学研究提供了一个辅助的演示系统。     

微电子工业的职业卫生

微电子工业代表一类高新技术企业,作业环境清洁度高,但化学物质使用集中,职业危害尚研究不足。本文简单介绍了其生产过程和化学物使用情况,综述了各种职业有害因素如化学、物理及工效学因素的暴露和健康应。主要化学物质有：金属、毒气、腐蚀性物质,有机溶剂,光活性物质,因其浓度常低于卫生标准或检出限,使接触评定较难进行。微电子工业职业有关疾患患病情况高于一般电子工业和所有制造业,目前对生育系统危害调查居多。进一步需评价化学物联合作用及调查职业有关的慢性疾病和癌症患病情况。     

近5年国内外图书情报学发展现状与研究热点

目的：梳理国内外图书情报学领域的发展现状与研究热点，为图书情报学领域的深入研究提供参考。方法：以Web of Science及《中文核心期刊要目总览》与“中文社会科学引文牵引”（CSSCI）收录的高影响力图书情报学期刊在2016-2020年所刊载的论文为数据源，通过可视化软件CiteSpace对作者、国家、机构、关键词等进行分析。结果：国内外均没有形成大范围相互联系的作者合作网络。西方发达国家在该领域的研究优势比较明显，形成了以美国为中心的世界范围内的合作网络。国外研究机构主要集中在高等院校和医院，国内集中在高等院校和科研院所。国外文献计量学研究、知识管理研究和医学信息学研究等越来越受到学者们的关注，国内研究仍处于探索阶段，与国外还存在较大差距。结论：未来应该加强该领域学者和机构间的交流与合作，丰富研究主题，提升我国在该领域的学术影响力。     

国内外ICU获得性衰弱干预研究的文献计量学与可视化分析

目的 通过梳理目前国内外有关ICU获得性衰弱干预的研究现状、热点与趋势,为后续该方面的研究提供思路。方法 检索中国知网及PubMed中ICU获得性衰弱干预的相关文献,运用CiteSpace、BICOMB软件对其进行数据的提取与分析。结果 纳入有效文献中文83篇、英文164篇；国内ICU获得性衰弱干预研究的数量呈大幅上升趋势,国外较平稳；国内热点干预措施主要为早期活动、中医穴位刺激、电刺激、胰岛素疗法、康复,国外主要为物理疗法、神经肌肉电刺激、康复。结论 英美两国于该研究领域中占主导地位；国内华东地区的研究力量最强。建议国内在该领域增强多中心合作意识、探索国外的类似干预在中国人群中的作用、增加不同干预之间的对比分析、基于循证构建干预策略、在继续探索中医干预对ICU-AW的影响的同时也要深剖其机制。     

基于科学知识图谱的针灸专利计量可视化研究＊

目的 运用专利计量可视化方法探索针灸技术热点及发展趋势，为针灸技术领域创新研究提供参考，提高针灸技术临床应用，加快针灸技术发展。方法 利用文献计量软件Citespace 5.5.R2对从建库以来至2020年收录在德温特专利数据库（Derwent Innovations Index，DII）的27177篇针灸相关专利文献进行总结、分析，并以可视化图谱的形式展现出针灸专利的申请量、学科分布，专利权人、发明人合作网络，专利技术热点、发展趋势等指标特征。结果 针灸专利申请量呈现逐年上升趋势；学科涉仪器、内科医学、工程学、化学、药物药剂学等方面；中国为发明人和专利权人最多的国家，成都中医药大学、湖南中医药大学、上海中医药大学、河南中医药大学是针灸技术创新的主要创新机构；热点技术领域集中在针灸治疗仪器设备创新、中医经络理论指导下的养生保健设备创新；技术创新的趋势是诊疗一体化、数字化、智能化。结论 运用专利计量可视化方法发现目前针灸专利技术发展较快，探测到目前针灸技术领域的热点及趋势，可为针灸技术创新研究提供参考。     

Phase-amplitude coupling of ripple activities during seizure evolution with theta phase

ObjectiveHigh-frequency activities (HFAs) and phase-amplitude coupling (PAC) are key neurophysiological biomarkers for studying human epilepsy. We aimed to clarify and visualize how HFAs are modulated by the phase of low-frequency bands during seizures.MethodsWe used intracranial electrodes to record seizures of focal epilepsy (12 focal-to-bilateral tonic-clonic seizures and three focal-aware seizures in seven patients). The synchronization index, representing PAC, was used to analyze the coupling between the amplitude of ripples (80–250 Hz) and the phase of lower frequencies. We created a video in which the intracranial electrode contacts were scaled linearly to the power changes of ripple.ResultsThe main low frequency band modulating ictal-ripple activities was the θ band (4–8 Hz), and after completion of ictal-ripple burst, δ (1–4 Hz)-ripple PAC occurred. The ripple power increased simultaneously with rhythmic fluctuations from the seizure onset zone, and spread to other regions.ConclusionsRipple activities during seizure evolution were modulated by the θ phase. The PAC phenomenon was visualized as rhythmic fluctuations.SignificanceRipple power associated with seizure evolution increased and spread with fluctuations. The θ oscillations related to the fluctuations might represent the common neurophysiological processing involved in seizure generation.     

Three-dimensional coronary angiography of the perfused rat heart

The purpose of this work was to visualize the whole three-dimensional coronary artery tree of the perfused beating rat heart using three-dimensional MRI. The spatial resolution amounts to 140 μm. Also, vessels having smaller diameters could be detected. Different strategies for the visualization of the three-dimensional coronary angiograms including maximum intensity projection, data thresholding, and segmentation, were shown. The coronary artery tree was best visualized by hysteresis threshold segmentation and subsequent surface reconstruction.     

Methods for spherical data analysis and visualization

A systematic analysis of the localization of objects in extra-personal space requires a three-dimensional method of documenting location. In auditory localization studies the location of a sound source is often reduced to a directional vector with constant magnitude with respect to the observer, data being plotted on a unit sphere with the observer at the origin. This is an attractive form of data representation as the relevant spherical statistical and graphical methods are well described. In this paper we collect together a set of spherical plotting and statistical procedures to visualize and summarize these data. We describe methods for visualizing auditory localization data without assuming that the principal components of the data are aligned with the coordinate system. As a means of comparing experimental techniques and having a common set of data for the verification of spherical statistics, the software (implemented in MATLAB) and database described in this paper have been placed in the public domain. Although originally intended for the visualization and summarization of auditory psychophysical data, these routines are sufficiently general to be applied in other situations involving spherical data.