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目的探讨脑后部可逆性脑病综合征CT及MRI影像学表现,为该病临床准确诊断提供参考。方法回顾性分析我院2010年8月-2014年10月期间所收治的8例脑后部可逆性脑病综合征患者临床CT及MRI影像学资料。结果经分析发现,4例患者MRI影像表现为:双侧顶枕叶基本对称分布,斑片状长T1长T2信号,T2FLAIR呈现为高信号。而DWI则主要呈等信号,增强扫描无明显强化。4例患者临床CT表现:其双侧大脑后循环供血区表现为斑片状、低密度区。结论临床应用MRI及CT检查可为脑后部可逆性脑病综合征诊断提供一定参考依据,从而提高临床诊断准确性,有利于临床疾病诊断、治疗及预后判断。 相似文献
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目的:研究急性一氧化碳中毒后迟发性脑病(DEACMP)患者的诱发电位(EP)、CT和脑电图(EEG)。方法:对46例DEACMP患者进行EP、CT和EEG检查。结果:异常率体感诱发电位(SEP)83%、视觉诱发电位(VEP)63%,脑干听觉诱发电位(BAEP)30%,CT71%,EEG100%。SEP中的P40、N50、P60和N75峰潜伏期(PL)比正常对照组显著延长。VEP的P100PL较对照组明显延长。BAEP的Ⅰ、Ⅲ和Ⅴ波PL及Ⅰ—Ⅲ、Ⅲ—Ⅴ和Ⅰ—Ⅴ峰间期(IPL)与对照组比较无显著性差异。结论:EP、CT和EEG结合临床观察,对DEACMP的定位诊断、病情判断与预后评估均有意义。 相似文献
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Background A growing body of research has demonstrated the presence of ongoing cognitive impairment in large numbers of ICU survivors.Objective This review offers a practical framework for practicing intensivists and those following patients after their ICU stay for the identification of cognitive impairment in ICU survivors.Conclusions Early detection of cognitive impairment in critically ill patients is an important and achievable goal, but overt cognitive impairment remains unrecognized in most cases. However, it can be identified by objective (test scores) or subjective evidence (clinical judgment, patient observation, family interaction). 相似文献
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Jared M. Bruce PhD Colin J. Harrington Suzanne Foster Holly James Westervelt 《The Clinical neuropsychologist》2013,27(6):909-925
The purpose of this study was to examine the relationship between common laboratory values and cognitive functioning among 129 inpatients referred for neuropsychological evaluation. Laboratory values were recorded at admission, at the time point closest to neuropsychological evaluation, and at the time of peak metabolic derangement. Cognitive status was evaluated with the modified Mini-Mental State Exam. Patients with hyperglycemia, hypochloremia, and/or elevated creatinine at admission exhibited cognitive deficits. Patients with hyperglycemia, hyperchloremia, hypernatremia, hyperkalemia, leukocytosis, low hemoglobin, elevated blood urea nitrogen, and/or elevated creatinine at the time of peak metabolic derangement exhibited cognitive deficits. Different lab abnormalities at the time of peak metabolic derangement accounted for unique patterns of neuropsychological impairment. Lab values drawn at the time point closest to neuropsychological evaluation were not significantly associated with cognitive functioning. Results support and quantify common clinical beliefs that metabolic abnormalities are associated with global cognitive changes among elderly inpatients. 相似文献
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Shunji Hasegawa Takeshi Matsushige Hirofumi Inoue Midori Takahara Madoka Kajimoto Hiroshi Momonaka Chiemi Ishida Saya Tanaka Tsuneo Morishima Takashi Ichiyama 《Brain & development》2013
Background: Influenza-associated encephalopathy (IE) is a serious complication during influenza viral infection. Common clinical symptoms of IE include seizures and progressive coma with high-grade fever. We previously reported that hypercytokinemia and monocyte/macrophage activation may play an important role in the pathogenesis of IE. CD163 is a scavenger receptor for hemoglobin–haptoglobin complexes and is expressed by monocytes/macrophages. Proteolytic cleavage of monocyte-bound CD163 by matrix metalloproteinases releases soluble CD163 (sCD163). However, there have been no reports regarding serum sCD163 levels in IE patients. Methods: We measured serum levels of sCD163 as a marker of monocyte/macrophage activation in IE patients with poor outcomes, those without neurological sequelae, influenza patients without IE, and control subjects. Results: Serum sCD163 levels were significantly higher in IE patients with poor outcomes than in those without neurological sequelae. In particular, sCD163 levels in cases of death were significantly higher than those in other cases. Conclusions: Our results suggest that monocyte/macrophage activation is related to the pathogenesis of severe IE. 相似文献
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We report herein the first case of psychosis after short-term use of the combined oral contraceptive (COC) pill in a young patient with no previous psychiatric history. An 11-year-old girl was placed on the COC pill for treatment of menorrhagia, 5 months after her menarche. She developed an initial encephalopathy, which progressed to psychosis. The estrogenic component of the COC pill is the most likely cause of this psychosis. COC pills should be used with caution in patients with an already high estrogenic state as occurs near menarche. 相似文献