轮班和白班护理人员睡眠质量调查

目的评估白班和轮班护理睡眠质量状况,为改善护士的睡眠质量、健康状况提供科学依据。方法 2011年,采用匹兹堡睡眠质量指数(Pittsburgh Sleep Quality Index,PSQI)量表对本医院260名护士进行调查。结果白班组PSQI总分大于7分者13人,睡眠障碍的发生率为10%,轮班组130人,睡眠障碍的发生率为55.5%。两组人群PSQI各因子及总分比较,差异有统计学意义(P<0.05)。结论轮班护士比白班护士有较差的睡眠质量,需采取多种干扰措施来提高护士的睡眠质量。     

孕妇的睡眠质量及心身状况初步研究

目的　了解孕妇在妊娠期的主观睡眠质量及心身状况。方法　采用匹茨堡睡眠质量指数量表 ( PSQI)及症状自评量表 ( SCL-90 )评定患者的主观睡眠质量及心身状况。结果　孕妇组与对照组 PSQI和 SCL-90各因子和总分进行比较 ,结果显示两组 PSQI睡眠时间、睡眠紊乱因子比较有显著性差异 ( P<0 .0 5)。SCL-90躯体化因子分统计差异有显著性 ( P<0 .0 5)。结论　与对照组比较 ,孕妇妊娠期睡眠时间增加 ,睡眠紊乱加重 ,同时躯体化不适症状多     

女珍颗粒联合佐匹克隆治疗更年期失眠症的临床研究

目的 探讨女珍颗粒联合佐匹克隆片治疗更年期失眠症的临床疗效。方法 选取2016年3月—2018年10月在内蒙古自治区精神卫生中心进行治疗的82例更年期失眠患者为研究对象,根据用药的差别分为观察组（41例）和对照组（41例）。对照组给予佐匹克隆片,7.5 mg/次,1次/d,睡前服用;观察组在对照组基础上口服女珍颗粒,6 g/次,3次/d。两组均治疗4周后进行效果对比。结果 经治疗,对照组有效率为82.92%,显著低于治疗组95.12%（P<0.05）。经治疗,两组患者匹兹堡睡眠质量指数量表（PSQI）评分降低;多导睡眠监测（PSG）中入睡时间、觉醒时间降低,总睡眠时间增加,睡眠效率提高;睡眠结构中I期时间缩短,II、III期及快速动眼期时间延长（P<0.05）,且观察组睡眠情况显著优于对照组（P<0.05）。经治疗,两组患者血清中神经递质去甲肾上腺素（NE）、5-羟色胺（5-HT）、多巴胺（DA）水平显著升高（P<0.05）,且观察组神经递质水平显著高于对照组（P<0.05）。经治疗,两组焦虑自评量表评分（SAS）、抑郁自评量表评分（SDS）、SCL-90、Hamilton抑郁量表（HAMD）评分均显著降低（P<0.05）,且观察组上述评分显著低于对照组（P<0.05）。结论 女珍颗粒联合佐匹克隆片治疗更年期失眠症效果良好,可有效减轻失眠症状,改善患者负面情绪,提高患者生活质量,有着良好临床应用价值。     

医科研究生睡眠质量与心理健康状况的关系

目的了解在校研究生睡眠质量情况及其与心理健康的关系 ,为心理健康教育提供参考。方法使用匹兹堡睡眠质量指数 (PSQI)和症状自评量表 (SCL 90 ) ,对 2 44名在校研究生进行睡眠及心理健康状况调查 ,并进行相关和回归分析。结果以PSQI总分≥ 8分作为判断睡眠质量问题的标准 ,有 7.8%的研究生有睡眠质量问题 ,男女生的比例分别为 6.7%和 10 .0 % ;睡眠状况不佳主要体现在日间功能障碍( 3 4.0 % )、睡眠时间不足 ( 2 4.6% ) ,入睡慢 ( 13 .9)和自感睡眠质量不佳 ( 11.1% )。研究生中博士和硕士 ,男性和女性 ,已婚者与未婚者的睡眠质量比较无显著差异。睡眠质量不同者的心理健康状况有显著差异 (P<0 .0 0 1) ,两两比较发现 ,睡眠越好 ,心理健康状况也越好 (P <0 .0 5 ) ;相关分析表明PSQI总分与SCL 90总均分间有显著的相关 (r =0 .5 0 1) ;多元逐步回归分析表明 :影响睡眠质量的心理症状因子主要为强迫和焦虑 ,这两个因素可解释PSQI总分变异的 2 6.4%。结论心理因素对研究生的睡眠质量有显著影响。     

复方苁蓉益智胶囊治疗帕金森病肝肾亏虚型失眠的疗效观察

目的 探讨复方苁蓉益智胶囊治疗帕金森病肝肾亏虚型失眠患者的临床疗效。方法 选取2019年1月-2020年6月长沙市第四医院帕金森疾病肝肾亏虚证型失眠患者60例作为研究对象,根据治疗方法将患者分为对照组和观察组,每组30例。对照组口服阿普唑仑片,0.4 mg/次,3次/d。观察组患者口服复方苁蓉益智胶囊,4粒/次,3次/d。两组均服用2周。观察两组患者的临床疗效和匹兹堡睡眠质量评分（PSQI）,同时比较两组患者的焦虑自评量表（SAS）、抑郁自评量表（SDS）、Barthel指数（BI）。结果 治疗后,观察组总有效率为86.70%,与对照组的90.00%相比,差异无统计学意义。治疗后,观察组的睡眠障碍评分、睡眠时间及日间功能评分均优于对照组（P<0.05）。治疗后,两组SAS、SDS评分均显著降低,观察组BI评分显著升高（P<0.05）;治疗后,观察组SDS评分显著低于对照组,BI评分高于对照组（P<0.05）。结论 复方苁蓉益智胶囊治疗帕金森病肝肾亏虚型失眠患者可有效改善睡眠质量,临床疗效显著。     

老年人睡眠障碍与认知损害的关系及相关影响因素分析

目的 探讨老年人认知损害与睡眠障碍的关系并且分析引起认知损害的影响因素,为改善老年人睡眠质量及认知功能提供参考.方法 2016年1月至2017年12月,石家庄市第八医院精二科门诊及病房,通过方便取样对152例伴有失眠的老年人进行问卷调查,并另选取150例健康志愿者(睡眠正常组)进行比较.采用匹茨堡睡眠质量指数量(PSQI)表、蒙特利尔认知评估(MoCA)评分表分别评估老年人的睡眠质量以及认知功能,Spearman相关系数法分析睡眠障碍与认知损害之间的关系,多因素logistic回归分析不同维度睡眠障碍对认知损害的影响.结果 152例睡眠障碍者的PSQI的平均得分为(14.67±1.68)分;其MoCA平均得分(16.79±3.89)分;相关分析结果表明,MoCA总分与各子项均与PSQI总分负相关;多因素logistic回归分析表明,睡眠时间、入睡时间以及日间功能障碍与发生认知损伤差异有统计学意义(P<0.05).结论 睡眠障碍的老年人中认知损害发生率增加,其中合理的睡眠时间、入睡时间可改善认知功能,对认知功能起保护作用;而日间功能障碍与认知损伤相互影响,可导致病情加重.     

Race and Financial Strain are Independent Correlates of Sleep in Midlife Women: The SWAN Sleep Study

Study Objectives:

To examine racial differences in sleep in a large cohort of midlife women and to evaluate whether indices of socioeconomic status (SES) are associated with racial differences in sleep.

Design:

Cross-sectional study.

Setting:

Participants'' homes.

Participants:

Caucasian (n = 171), African American (n = 138) and Chinese women (n = 59).

Interventions:

None.

Measurements:

Sleep quality was assessed with the Pittsburgh Sleep Quality Index. Polysomnographically assessed sleep duration, continuity, architecture, and NREM electroencephalograhic (EEG) power were calculated over multiple nights. Sleep disordered breathing and periodic leg movements were measured on a separate night. Linear regression analysis was used to model the independent and synergistic effects of race and SES on sleep after adjusting for other factors that impact sleep in midlife women. Indices of SES were self-reported educational attainment and financial strain.

Results:

Sleep was worse in African American women than Caucasian participants as measured by self-report, visual sleep stage scoring, and NREM EEG power. Slow wave sleep differences were also observed between Chinese and Caucasian participants. Racial differences persisted after adjustment for indices of SES. Although educational attainment was unrelated to sleep, financial strain was associated with decreased sleep quality and lower sleep efficiency. Financial strain-by-race interactions were not statistically significant, suggesting that financial strain has additive effects on sleep, independent of race.

Conclusions:

Independent relationships between race and financial strain with sleep were observed despite statistical adjustment for other factors that might account for these relationships. Results do not suggest that assessed indices of SES moderate the race-sleep relationship, perhaps due to too few women of low SES in the study.

Citation:

Hall MH; Matthews KA; Kravitz HM; Gold EB; Buysse DJ; Bromberger JT; Owens JF; Sowers M. Race and financial strain are independent correlates of sleep in midlife women: the SWAN sleep study. SLEEP 2009;32(1):73-82.     

Diurnal time course of heat pain perception in healthy humans

Rapid skin heating by infrared lasers can be used to investigate the integrity of the nociceptive system by activating A-delta and C fibers. The aim of our study was to analyze if healthy humans exhibit any clinically relevant diurnal variations in their heat pain sensitivity. Circadian A-delta fiber function was analyzed by studying N2 and P2 components of laser-evoked potentials (LEP) and pain thresholds evoked by laser stimulation of the foot every 2h from 8a.m. to 10p.m. in 15 healthy subjects. Heat stimuli were generated by an infrared Tm-YAG laser and were delivered to an area of 4 cm × 4.5 cm on the dorsum of the right or left foot in 3 runs of incremental and decremental intensities. After each stimulus subjects were asked to classify the intensity of pain with a numeric rating scale (NRS). LEPs were recorded with fixed stimulus intensities that were 1.5× of the pain threshold. Data were collected with the SynAmps System (Neuroscan, El Paso, USA) and averaged across 35-40 trials. Laser-induced heat pain thresholds and circadian latencies of LEP did not significantly vary during the day. Our results correspond with previous studies that did not detect any consistent significant diurnal variations in perception of heat pain perception using contact thermodes. The intensity of pain perception did not demonstrate any correlation with mood or sleep parameters as measured with the Beck Depression Inventory (BDI), the subjective sleep scales Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS).     

福州地区综合性大学本科生睡眠状况调查及其干预的研究

目的了解福州地区综合性大学本科生睡眠状况,为心理健康教育提供依据。方法用匹兹堡睡眠质量指数问卷（PSQI）,对328名福州市综合性大学本科生进行调查。结果①大学生睡眠质量总分为5.51±2.28,睡眠状况不佳的有22.9%;②性别对主观睡眠质量、睡眠障碍和总体睡眠质量有影响;③不同年级大学生的睡眠情况存在显著差异;④专业因素对睡眠障碍有影响;⑤拥有电脑情况对睡眠障碍有影响。结论应重视大学生睡眠状况,有针对性地加强睡眠咨询和干预。     

磁珠耳压法治疗糖尿病失眠症临床研究

目的:观察磁珠耳压法治疗糖尿病失眠症的临床疗效。方法:70例糖尿病失眠症患者按照随机数字表法分为观察组和对照组,各35例。观察组给予耳穴压磁珠疗法,对照组给予舒乐安定,两组均治疗1个月。比较两组治疗后匹兹堡睡眠质量指数(pittsburgh sleep quality index,PSQI)量表评分及临床疗效。结果:治疗前两组PSQI量表总分及各项评分比较,差异均无统计学意义(P0.05)。治疗后两组PSQI总分、睡眠质量、睡眠时间、睡眠效率、睡眠障碍、日间功能障碍评分均降低,与治疗前比较,差异均有统计学意义(P0.05);观察组治疗后各项评分与对照组比较,差异亦有统计学意义(P0.05)。观察组有效率84.8%,对照组有效率为71.9%,两组比较,差异有统计学意义(P0.05)。结论:磁珠耳压法治疗糖尿病失眠症临床疗效显著。