健康教育对倒班医务人员睡眠质量和生活质量的影响

目的研究倒班对医务人员睡眠质量和生活质量的影响及其影响因素,为进一步改善倒班医务人员睡眠质量和生活质量提供依据。方法采用分层整群随机抽样的方法,抽取广东省番禺区南村医院106名医护人员,应用匹茲堡睡眠质量指数量表（PSQI）评价患者的睡眠质量,应用生存质量评定量表简表（WHOQOL）评价倒班医务人员的生活质量,比较健康教育干预前后倒班医务人员睡眠质量和生活质量的变化。结果健康教育后倒班人员睡眠质量和生活质量比干预前有显著提高（P〈0.05）。分析显示,女性、婚姻状况不稳定、健康状况差是睡眠质量差的危险因素。结论健康教育干预对改善倒班医务人员的生活质量和睡眠质量有促进作用。     

CPAP对OSAHS患者睡眠质量的影响分析

目的观察持续正压通气（CPAP）治疗阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的临床疗效,并评价对患者睡眠质量的影响。方法对56例已行多导睡眠监测（PSG）的中重度OSAHS患者在CPAP治疗前后分别采用匹兹堡睡眠质量指数（PSQI）量表了解他们的睡眠情况。并查阅患者治疗后的呼吸暂停低通气指数（AHI）的变化情况。结果 CPAP治疗后的AHI明显降低（P〈0.01）;PSQI总分和其因子分中的睡眠质量、睡眠效率、睡眠障碍、日间功能明显改善（P〈0.01）。结论 CPAP能显著改善OSAHS患者睡眠情况下的呼吸紊乱,并能使其主观睡眠质量得到明显改善;PSQI量表可作为基层医院评定OSAHS患者睡眠质量的工具之一。     

女珍颗粒联合佐匹克隆治疗更年期失眠症的临床研究

目的 探讨女珍颗粒联合佐匹克隆片治疗更年期失眠症的临床疗效。方法 选取2016年3月—2018年10月在内蒙古自治区精神卫生中心进行治疗的82例更年期失眠患者为研究对象,根据用药的差别分为观察组（41例）和对照组（41例）。对照组给予佐匹克隆片,7.5 mg/次,1次/d,睡前服用;观察组在对照组基础上口服女珍颗粒,6 g/次,3次/d。两组均治疗4周后进行效果对比。结果 经治疗,对照组有效率为82.92%,显著低于治疗组95.12%（P<0.05）。经治疗,两组患者匹兹堡睡眠质量指数量表（PSQI）评分降低;多导睡眠监测（PSG）中入睡时间、觉醒时间降低,总睡眠时间增加,睡眠效率提高;睡眠结构中I期时间缩短,II、III期及快速动眼期时间延长（P<0.05）,且观察组睡眠情况显著优于对照组（P<0.05）。经治疗,两组患者血清中神经递质去甲肾上腺素（NE）、5-羟色胺（5-HT）、多巴胺（DA）水平显著升高（P<0.05）,且观察组神经递质水平显著高于对照组（P<0.05）。经治疗,两组焦虑自评量表评分（SAS）、抑郁自评量表评分（SDS）、SCL-90、Hamilton抑郁量表（HAMD）评分均显著降低（P<0.05）,且观察组上述评分显著低于对照组（P<0.05）。结论 女珍颗粒联合佐匹克隆片治疗更年期失眠症效果良好,可有效减轻失眠症状,改善患者负面情绪,提高患者生活质量,有着良好临床应用价值。     

神经症患者的睡眠状况及相关研究

目的 了解神经症患者的睡眠状况,探索影响神经症患者睡眠状况的主要因素,并进一步探讨睡眠状况自评量表(SRSS)和匹兹堡睡眠质量指数(PSQI)的相关性.方法 使用SRSS和PSQI对河北省第六人民医院104名神经症患者的睡眠状况进行调查研究,进而分析神经症患者的睡眠状况及相关因素.结果 神经症患者的得分显著高于一般人群...     

石河子大学在校大学生睡眠质量与心理健康状况的调查研究

目的了解石河子大学在校大学生睡眠质量与心理健康状况的关系,为改善大学生睡眠质量和提高心理健康水平提供参考和依据。方法通过随机抽样,采用匹兹堡睡眠质量指数调查表（PSQI）,症状自评量表（SCL-90）及一般情况调查表对石河子大学1362名在校生进行调查。结果①以PSQI总分≥8作为判断睡眠质量差的标准,睡眠质量差的有335人（24．6％）,男女分别为26．4％和22．8％（P〈0．05）;睡眠质量不佳主要表现在日间功能障碍（65．9％）,主观睡眠质量（24．8％）,入睡时间（29．9％）;②PSQI总均分男女生分别为6．05±2．82和5．76±2．47,男生得分高于女生（P〈0．05）;男生在入睡时间和睡眠效率平均得分显著高于女生（P〈0．01）;③睡眠质量差的组在SCL-90总均分和各因子均分得分均明显高于睡眠质量良和睡眠质量一般的两组（P〈0．01）;④PSQI各成份分及总分与SCL-90各因子均分及总均分间存在正相关关系（P〈0．01）。结论大学生睡眠质量与心理健康状况高度相关,因此要积极关注大学生的睡眠质量问题。     

肿瘤科护士睡眠质量的调查

目的 探讨专科医院肿瘤科护士睡眠质量现状,分析影响某专科医院肿瘤科护士睡眠质量的因素.方法 采用匹兹堡睡眠质量指数（PSQI）量表对108名肿瘤科护士睡眠质量进行调查及相关分析.结果 肿瘤科护士PSQI得分明显高于国内正常成人组,除睡眠质量与睡眠时间外,总分及其他5个成分得分差异均有统计学意义（P＜0.01）;46.3%的肿瘤科护士睡眠质量差,PSQI总分＞7分;不同职称、工龄、夜班频数肿瘤科护士睡眠质量差异有统计学意义（P＜0.05）;不同科室、年龄、学历、婚姻状况肿瘤科护士睡眠质量差异无统计学意义（P＞0.05）.结论 肿瘤科护士睡眠质量差,职称、工龄、夜班频数是肿瘤科护士睡眠质量的影响因素.     

药物治疗联合道家认知疗法治疗中老年失眠症对照研究

目的：探讨药物治疗联合道家认知疗法治疗中老年失眠症的临床疗效。方法将101例中老年失眠症患者随机分为两组。两组均口服佐匹克隆治疗,研究组予以道家认知治疗,对照组予以常规健康教育。观察12周。于治疗前后采用匹兹堡睡眠质量指数评定睡眠状况,症状自评量表、社会支持量表、特质应对方式问卷评定临床症状、社会支持状况及应对方式。结果治疗6周末起两组匹兹堡睡眠质量指数总分较治疗前显著降低（P＜0．01）,研究组显著低于对照组（P＜0．01）;治疗12周末研究组症状自评量表评分较治疗前显著降低（P＜0．01）,社会支持量表主观支持、支持利用度维度分较治疗前显著升高（P＜0．01）,特质应对方式问卷积极应对维度分较治疗前显著升高（P＜0．01）,消极应对维度分较治疗前显著降低（P＜0．01）,与对照组比较差异均有显著性（P＜0．05或0．01）。结论药物联合道家认知疗法能显著改善中老年失眠症患者的睡眠状况和躯体症状,对提高社会支持利用度,改善积极应对方式具有重要作用,显著优于单用药物治疗。     

Acupuncture and related therapies for poststroke insomnia: A protocol for systematic review and network meta-analysis

Objective:To compare and evaluate the clinical effects on patients with poststroke insomnia of various acupuncture and acupuncture-related therapies.Methods:In order to analyze the direct and indirect evidence from related studies, we used network meta-analysis (NMA). In order to collect randomized controlled trials (RCTs) of acupuncture and related therapies in the treatment of poststroke insomnia, 3 English and 4 Chinese databases were searched. After 2 researchers independently screened the literature, extracted the information, and assessed the probability of bias in the included studies, the data was analyzed using Stata15.0 and WinBUGS1.4.3 software.Results:Based on the existing data, the pros and cons of different acupuncture-related therapies are compared extensively, the effectiveness of different acupuncture-related therapies is ranked compared to drugs with hypnotic effect in poststroke insomnia care, and the best methods or combinations of acupuncture intervention are summarized.Conclusion:This study will provide new evidence for the safety and effectiveness of acupuncture-related therapies in the treatment of poststroke insomnia, and may be helpful for clinicians, poststroke insomnia patients, and clinical guideline makers to choose the optimal combination of acupuncture for the treatment of poststroke insomnia.Registration Number:INPLASY202120028.     

Effectiveness and safety profiling of zolpidem and acupressure in CKD associated pruritus: An interventional study

Background:Chronic kidney disease (CKD)-associated pruritus (CKD-aP) contributes to poor quality of life, including reduced sleep quality and poor sleep quality is a source of patient stress and is linked to lower health-related quality of life. This study aimed to investigate the effectiveness of zolpidem 10 mg and acupressure therapy on foot acupoints to improve the sleep quality and overall quality of life among hemodialysis patients suffering from CKD-aP.Method:A multicenter, prospective, randomized, parallel-design, open label interventional study to estimate the effectiveness of zolpidem (10 mg) oral tablets versus acupressure on sleep quality and quality of life in patients with CKD-aP on hemodialysis. A total of 58 hemodialysis patients having sleep disturbance due to CKD-aP completed the entire 8-week follow-up. The patients were divided into a control (acupressure) group of 28 patients and an intervention (zolpidem) group of 30 patients.Results:A total of 58 patients having CKD-aP and sleep disturbance were recruited. In the control group there was a reduction in the PSQI score with a mean ± SD from 12.28 ± 3.59 to 9.25 ± 3.99, while in the intervention group the reduction in PSQI score with a mean ± SD was from 14.73 ± 4.14 to 10.03 ± 4.04 from baseline to endpoint. However, the EQ5D index score and EQ-visual analogue scale (VAS) at baseline for the control group with a mean ± SD was 0.49 ± 0.30 and 50.17 ± 8.65, respectively, while for the intervention group the values were 0.62 ± 0.26 and 47.17 ± 5.82, respectively. The mean EQ5D index score in the control group improved from 0.49 ± 0.30 to 0.53 ± 0.30, but in the intervention group there was no statistical improvement in mean EQ5D index score from 0.62 ± 0.26 to 0.62 ± 0.27 from baseline to week 8. The EQ 5D improved in both groups and the EQ-VAS score was 2.67 points higher at week 8 as compared to baseline in the control group, while in the intervention group the score was 3.33 points higher at week 8 as compared to baseline. Comparing with baseline, the PSQI scores were significantly reduced after week 4 and week 8 (P =  < .001). Furthermore, at the end of the study, the PSQI scores were significantly higher in the control as compared to the intervention group (P = .012).Conclusion:An improvement in sleep quality and quality of life among CKD-aP patients on hemodialysis has been observed in both the control and intervention groups. Zolpidem and acupressure safety profiling showed no severe adverse effect other that drowsiness, nausea and daytime sleeping already reported in literature of zolpidem.     

Cystic fibrosis patients have poor sleep quality despite normal sleep latency and efficiency

STUDY OBJECTIVES: Cystic fibrosis (CF) patients may be predisposed to poor sleep quality due to upper and lower airway abnormalities and impaired gas exchange. Previous sleep investigations of CF patients using single-night polysomnography have reported conflicting results. We hypothesized that sampling sleep for a prolonged period in a patient's normal environment may give a more representative assessment of sleep quality than a single-night polysomnogram, and that impaired sleep quality would correlate with pulmonary disease severity and self-assessed sleep quality. DESIGN: Using wrist actigraphy, we measured sleep quality in clinically stable CF patients and age-matched control subjects. In addition, each CF patient and control subject completed the following three questionnaires: the Epworth sleepiness scale; the Pittsburgh sleep quality index (PSQI); and the Medical Outcomes Study 36-item short form. RESULTS: Twenty CF patients and control subjects were enrolled in the study, and were well-matched for age, sex, and body mass index. The mean (+/- SD) FEV(1) for CF patients was 61.0 +/- 20.1% predicted. CF patients and control subjects had similar sleep duration, sleep latency, and sleep efficiency. However, CF patients had higher PSQI scores (6.45 vs 4.55, respectively; p = .04), a higher fragmentation index (FI) [31.72 vs 18.02, respectively; p < 0.001], and less immobile time (88.87 vs 91.89, respectively; p = 0.02). There was a significant correlation of FI with FEV(1) and PSQI scores. CONCLUSIONS: Stable CF patients have disrupted sleep, and sleep disruption may in part be related to the severity of pulmonary disease. In addition, the PSQI may be useful in detecting CF patients with poor sleep quality.