卡巴胆碱对烧伤延迟复苏大鼠免疫功能的影响

Objective To explore the changing trend of Ia on monocyte, lymphocyte apoptosis rate, TNF-α and IL-6 in abdominal aorta of burned rats with delayed resuscitation and the influence of application of carbachol on them. Methods Adult male Wistar rats were randomly divided into normal control group(n =8), scald group(n =48) and scald with carbachol treatment group(n =48). In latter two groups, rats were inflicted with 30% total body surface area (TBSA) full-thickness scald and delayed fluid resuscitation. All scald rats were sacrificed at the 6th hours or 1st, 2nd, 3rd, 7th, 14th day after scald, with 8 rats at each time point. Expression of Ia antigen on monocyte and lymphocyte apoptosis rate were determined by direct immunofluorescence on a flow cytometer, and TNF-α and IL-6 was measured by ELISA. Results Expression of la on monocyte was obviously lower than that of controls. The lowest levels were recorded on the 6th hours and 1st day after scald. Subsequently, Ia was elevated gradually, but still lower than that of normal rats(P <0. 01). After administration of carbachol, Ia expression was obviously promoted, compared with the simple scald group (P <0. 01). Lymphocyte apoptosis rate, TNF-α and IL-6 was higher than that of controls(P <0. 01). After administration of cavachol, , lymphocyte apoptosis rate and TNF-α and IL-6 was obviously down-regulated on the 6th hours, 1st day, 2nd day and 3rd day after scald injury, compared with the simple scald group (P < 0. 01 or 0. 05). Conclusion After severe burn with delayed fluid resuscitation, there is a low la expression, high lymphocyte apoptosis rate and increased releasing of proinflammatory cytokine. Immune function was suppressed. Carbacho] could improve the immune function of scald rats with delayed fluid resuscitation.     

足反射特法治愈3例尿结石

尿路结石是泌尿系统的常见病。泌尿系统的所有器官，即肾、输尿管、膀胱、尿道，都可发生结石病。本病好发于青壮年，男性多于女性。尿结石发生的主要原因是饮食结构不科学，如饮食口味偏咸、喜吃甜食、过多摄取高蛋白、高脂肪及高磷食物、习惯性饮水少等。结石大小不同，小的如米粒、黄豆大小，大的有几厘米，可以堵塞肾及输尿管，使尿液无法排出。     

高血压伴肾功能减退的患者，如何正确选用降压药

长期高血压可引起心、脑、肾等靶器官的损害，最后可导致心、脑、肾功能衰竭的严重后果。一般来说，在高血压早期相当长一段时间内，并不会引起明显的肾脏病变。只是表现为对高钠或血容量扩张的适应能力减弱，如饮食过咸，饮水过多时，易出现水肿，血压上升。     

居&#183;家&#183;向&#183;导

咸肉过咸咋处理；巧除鱼胆苦味；凉拌海参别放醋；怎样用电饭锅更节电；吃完螃蟹怎样除腥味     

肾气丸加味治愈咸乳2例

肾气丸加味治愈咸乳２例３１５７３１浙江省象山台胞医院金家隆成乳之证，临床并不多见，笔者从事临床多年，治疗２例，均用肾气丸加味获愈，现介绍如下。例一林某，２８岁。车门三村人。１９７３年５月２０日初诊。主诉：哺乳６个月，因乳汁不足，加服甜食流汁后，婴儿从...     

论清道、成时期的西北史地研究

在晚清西北史地学的发展过程中，道、成时期是人们关注最多的一个阶段。它与这一时期涌现出的西北史地名家与名著的贡献密切相关。但另一方面，在这些学者中初步形成的一种治学上的群体效应才是真正将西北史地研究发扬光大的关键因素。     

王庆国治疗口味异常经验

口酸证属饮食积滞者,应调和脾胃以消化积食,予半夏泻心汤合消食导滞之品治疗;口苦证属少阳枢机不利者,应和解少阳、疏利气机,予小柴胡汤加减治疗;口甜证属湿热蕴脾者,应健脾益气、清利湿热,予参苓白术散合葛根芩连汤加减治疗;口辣证属肺热上逆者,应清肺胃伏火,予半夏泻心汤加清热养阴之品治疗;口咸证属肾液上泛者,予补肾益精,善用当...     

基于"过咸伤骨"理论探讨高盐摄入与原发性骨质疏松症的相关性

中医理论在揭示原发性骨质疏松症(POP)的病因病机以及指导POP的防治方面均具有独特优势.《内经》中的咸入肾,肾主骨,过咸伤骨理论准确地阐释了中医五味之咸的过多摄入导致骨骼失养的病理进程.该理论亦与现代医学研究中高盐摄入可直接或间接引起骨量减少,最终导致POP的发生、发展高度契合.但目前现代医学对高盐摄入与POP的...     

常饮牛奶及饮食口味偏咸与脑卒中的关系

目的 探讨某些饮食习惯与脑卒中的关系。方法 采用医院为基础的配比病例对照研究方法,对经颅脑CT扫描确诊的320例脑卒中病例及各自的对照通过条件logistic回归程序作1：1配比分析。结果 单因素分析结果表明,经常喝牛奶者脑卒中的OR为0．70（95％CI：0．53－0．92）,口味偏咸使脑卒中的危险性增加,OR为1．42（95％CI：1．06－1．91）。按高血压病史调整后,以上作用均失去显著意义（OR分别为0．59,95％CI：0．29－1．22和1．26,95％CI：0．87－1．82。结论 经常喝牛奶对中老年人脑卒中的发病具有保护作用,口味偏咸可使脑卒中的危险性增加,这些作用可能是借助于对高血压的影响来实现的。未发现饮茶习惯与脑卒中有关。