Tumoral Calcinosis

ABSTRACT. Tumoral calcinosis is a rare entity of unknown etiology. In this condition nodular calcareous masses are deposited in the soil tissues around juxtaarticular areas. It occurs in young healthy subjects with normocalcemia. Hyperphosphatemia is only rarely present.     

不同程度退行性钙化心脏瓣膜中Ca,P,Mg元素含量测定及其意义

目的：研究探讨心脏瓣膜中Ｃａ的沉积形式及Ｍｇ对退行性心脏瓣膜钙化程度的可能影响。方法：首次应用微量元素测定方法测定了不同钙化程度心脏瓣膜钙（Ｃａ）磷（Ｐ）、镁（Ｍｇ）元素含量。结果：心脏瓣膜中Ｃａ、Ｐ含量随钙化程度加重而明显增加，两者呈高度正相关，而Ｃａ／Ｐ则相对稳定。Ｃａ／Ｍｇ随钙化程度加重而明显升高，但Ｍｇ含量相对稳定。结论：瓣膜中Ｃａ主要以非晶型的磷氢钙形式沉积；Ｍｇ的相对减少可能是钙化程度     

Idiopathic tumoral calcinosis involving the cervical spine

We report a case of a 12-year-old girl with idiopathic tumoral calcinosis of the neck. There are calcium deposits in the paraspinal soft tissue with bony involvement in the cervical spine. CT and MR images are presented along with clinical and pathological features. Bony involvement in this disease has not been recognized before.     

老年人退行性心脏瓣膜病临床观察

对186例病人常规进行心脏超声检查,确诊老年退行性心脏瓣膜病(DCVD)病人46例,检出率为24.7%,50岁以上、60岁以上和70岁以上检出率分别为28.6%,43.0%和60.5%,随着年龄增加,检出率亦增加,统计学处理,P<0.005,瓣膜钙化主动脉瓣多于二尖瓣(P<0.005),亦有联合瓣膜病变。受累瓣膜近半数发生启闭异常,多为主动脉瓣关闭不全。超声检查可显示瓣膜钙化的特征性改变。并对DCVD的发病情况、病理特点、临床表现及诊断进行初步探讨。     

颅咽管瘤钙化灶元素组成与微观结构的研究

目的分析颅咽管瘤钙化灶的元素组成及微观结构,探索不同程度钙化间的区别。方法筛选50例颅咽管瘤病例,从肿瘤标本中分离出钙化斑块进行X-线衍射分析及X-线能量色散谱分析。结果 所有钙化斑块均由羟基磷灰石晶体及一些非晶态物质构成,钙化斑块中主要含有钙、磷、碳、氧4种元素,钙、磷、碳3种元素的百分含量在不同钙化程度的分组间具有显著差异(P<0.05),其中钙、磷元素含量与钙化程度呈正相关(rp分别为0.745和0.778,P<0.01),碳元素含量与钙化程度呈负相关(rp=-0.526,P<0.01)。结论不同钙化程度的钙化斑块中钙、磷、碳3种元素的含量不同,3种元素含量的不同影响钙化斑块的钙化程度。     

Diffuse cutaneous calculi (subepidermal calcified nodules): Case study

Four forms of calcinosis cutis exist: metastatic calcinosis, dystrophic calcinosis, idiopathic calcinosis, and subepidermal calcified nodules, usually referred to as cutaneous calculi because single, small, raised, hard nodules are present. Occasionally, there are two or three nodules, and in some instances there are numerous or even innumerable nodules. Most patients are children, but in some patients, a nodule is present already at birth or does not appear until about adult life; in some instances, the surface of the nodule is verrucous, but it may be smooth. The most common location of the nodule is the face. A 12‐year‐old Yemeni child patient presented with warty, hard‐ and smooth‐surface, white, and small and large non‐itchy numerous nodules in the face and in the four extremities, which started at 4 years after birth, of 8 years' duration. Serum levels of calcium, phosphorous, and parathyroid hormones were normal. Plain chest X‐ray, abdominal ultrasonography, and complete blood count picture were normal. Skin biopsy followed by histopathological examination was diagnostic. The patient was treated with curettage and surgical removal.     

稳定型心绞痛冠状动脉斑块结构与重构关系的研究

目的:探讨血管内超声对稳定型心绞痛(SAP)患者冠状动脉(冠脉)病变斑块结构与血管重构关系的评估价值。方法:在冠脉介入治疗前应用血管内超声对SAP患者的冠脉病变进行研究。根据测定的重构指数(RI)将患者分为A组(负重构,RI<1.0)和B组(正重构,RI≥1.0),根据管腔面积狭窄率分为管腔面积狭窄率<70%组(轻中度狭窄组)和管腔面积狭窄率≥70%组(重度狭窄组)。结果:①与A组比较,B组近端参考段斑块负荷小,病变处的管腔面积和外弹力膜面积大、斑块负荷小,硬斑块所占比例少,病变处最大钙化弧度和长度小;②与轻中度狭窄组比较,重度狭窄组负重构多,软斑块少,病变处管腔面积小,病变处斑块面积和斑块负荷大,RI偏小,病变最大钙化弧度大。结论:不同程度管腔狭窄的SAP患者中,斑块钙化在负重构和严重管腔狭窄中占优势,负重构更常见于严重狭窄病变。