Establishment of a scoring system for predicting the difficulty level of high-intensity focussed ultrasound ablation of uterine fibroids

Purpose: To establish a scoring system that predicts the difficulty level of high-intensity focussed ultrasound (HIFU) ablation of uterine fibroids.

Materials and methods: Four hundred and twenty-two patients with fibroids were enrolled. The energy efficiency factor (EEF) and sonication time were set as dependent variables, with factors possibly affecting EEF and sonication time including age, body mass index (BMI), the volume of fibroids, the location of the uterus, the type of fibroids, the signal intensity on the T2-weighted imaging (T2WI), the enhancement type, the thickness of the rectus abdominis and the subcutaneous fat layer, the distance from the anterior/posterior surface of the fibroid to the skin, and the abdominal wall scars were set as predictors for building optimal scaling regression models.

Results: The volume of the fibroids, the location of the uterus, the signal intensity on T2WI, enhancement type, rectus abdominis thickness, subcutaneous fat thickness, and distance from the anterior surface of fibroid to the skin were related to EEF. Signal intensity on T2WI, the volume of fibroids, distance from the posterior surface of fibroid to the skin, and enhancement type were related to sonication time. Models that can predict the difficulty level of HIFU for fibroids have been established: for EEF, y?′?=?0.338X?′₁???0.231X?′₂+0.156X?′₃+0.167X?′₄?; for sonication time, y?=?0.227X₁+0.321X₂+0.157X₃+0.194X₄.

Conclusions: A scoring system for predicting the difficulty level of HIFU treatment for uterine fibroids has been established and it can be used to help select patients and to predict the sonication time for a given fibroid.     

Why women may live longer than men do? A telomere-length regulated and diet-based entropic assessment

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Metabolic scaling law for mouse fetal and placental weight

Human birth weight does not scale linearly with the weight of the placenta: placental mass (PM) is proportional to the fetal mass (FM) raised to the scaling exponent of 0.75 (PM ∼ FM^0.75) 1 and 2. The mouse is a common model for studying genetic and physiological backgrounds of placental development, function and pathologies. However, to date it has not been known how placental weight scales relative to embryo weight in mice.     

不同钾肥施用量对二年生射干生长、产量和品质的影响

目的 探究不同钾肥施用量对二年生射干生长、产量和品质的影响，为实现射干的高产优质栽培提供合理的施钾依据。方法 在施用氮肥、磷肥均为120 kg·hm^-2的基础上，设置0（K₀）、60（K₆₀）、120（K₁₂₀）、180（K₁₈₀）、240（K₂₄₀） kg·hm^-2共5个施钾处理，通过大田试验研究不同钾肥施用量处理对二年生射干农艺性状、药材产量、黄酮类成分含量和钾肥利用效率的影响。结果 施用钾肥可促进射干根系发育及分蘖苗产生，显著提高射干药材产量，与K₀处理相比增施钾肥射干增产16.0%~44.0%，其中K₁₈₀处理射干产量最高。不同钾肥施用量处理组均能促进射干根茎中的药效成分黄酮类物质的积累，其中K₁₂₀处理组芒果苷、射干苷、野鸢尾苷、鸢尾黄素、野鸢尾黄素、次野鸢尾黄素6种黄酮类成分的总积累量与K₀处理组比较增加33.2%；同时还能促进射干氮、钾、镁、铁、锌等元素的积累。随钾肥施用量增加，射干根茎钾积累量呈现先增加后减小趋势；偏生产力和根茎及叶片吸收率呈现逐渐降低的趋势；而钾肥的农学效率则在低钾至中高钾施用量时较高，达到高钾状态后明显下降。结合主成分分析对射干综合品质得分进行排名，由高到低的顺序为K₁₂₀>K₁₈₀>K₂₄₀>K₆₀>K₀。结论 综合考虑二年生射干产量、品质、钾肥利用效率等因素，在团风县射干种植生产中推荐钾肥施用量以120~166 kg·hm^-2为宜。     

儿童细菌性脑膜炎与病毒性脑炎临床及实验室检查特点

目的研究儿童细菌性脑膜炎与病毒性脑炎临床特点及血清基质蛋白金属酶-9(MMP-9)、降钙素原(PCT)、β2-微球蛋白(β2-MG)及C-反应蛋白(CRP)水平,分析各指标对两者鉴别诊断价值。方法选取2017年10月-2019年10月郑州大学附属儿童医院细菌性脑膜炎和病毒性脑炎患儿共80例,其中细菌性脑膜炎组49例,病毒性脑炎组31例,观察患儿症状,同时检测血清MMP-9、PCT、β2-MG和CRP水平并进行比较,作受试者工作特征曲线(ROC)分析各指标对细菌性脑膜炎和病毒性脑炎鉴别诊断价值。结果细菌性脑膜炎组患儿意识障碍、囟门张力增加和肺炎发生率高于病毒性脑炎组,精神萎靡、嗜睡和皮疹发生率低于病毒性脑炎组,差异有统计学意义(P<0.05);细菌性脑膜炎组血清MMP-9、PCT、β2-MG和CRP水平高于病毒性脑炎组,差异有统计学意义(P<0.05);意识障碍、肺炎以及血清CRP和PCT水平对细菌性脑膜炎和病毒性脑炎患儿鉴别诊断的敏感度分别为46.93%、46.93%、75.51%和83.67%,特异度分别为77.42%、80.65%、83.87%和90.32%,各指标联合诊断的曲线下面积为0.917,敏感度为91.84%,特异度为83.87%。结论细菌性脑膜炎和病毒性脑炎患儿临床特点和血清MMP-9、PCT、β2-MG和CRP水平均存在明显差异,综合各项指标进行分析可为临床鉴别诊断提供参考信息。     

基于DEA模型的生活垃圾转运站产能及效率评价的初步研究

结合最新颁布实施的CJJ/T 156—2010生活垃圾转运站评价标准,选取相应评价指标,采用DEA模型对垃圾转运站的产能及效率进行评价,并通过MATLAB程序,使评价模型操作简单化。     

分合式（Y型）输液器在优质护理服务中的效果体会

目的探讨分合式输液器在优质护理服务中的应用。方法选择2012年6～12月在胸外科静脉输液的患者，对照组（n=520）使用普通输液器；试验组（n=542）使用分合式输液器，采取单盲方法，收集每日更换液体的次数、输液器异常情况次数、患者的满意度，进行统计学分析。结果更换液体的次数、异常情况次数及患者的满意度，两组差异有统计学意义（P〈0．05）。结论使用分合式输液器，可以有效减少护士耗费在静脉治疗上的时间，提高工作效率，减轻患者及家属的恐慌，增加患者的满意度，便于优质护理工作的开展和完善。     

吉安市2009—2010年疾病预防控制工作机构绩效考核分析

目的：分析工作开展取得的成绩及其影响因素，进一步规范疾病预防控制工作。方法：通过绩效考核指标评估体系，量化104个机构指标，将2009年、2010年指标评分情况进行分析比较。结果：2010年比2009年的绩效考核工作有较大的提高，但仍有一些工作的开展受到限制。结论：绩效考核工作应争取政府和卫生行政部门的重视，加强部门间协作，改进评价方式。