金泽荣和中国文化名人的诗文交往

1905年朝鲜李朝王廷弘文馆纂辑所正三品通政大夫金泽荣流亡中国,在张謇的帮助下寓居南通,任翰墨林书局编校。金泽荣在南通出版了30余部著作,为保存祖国文化,同时也为翰墨林书局出版事业的发展繁荣作出了杰出贡献。案牍之余,金氏广泛结交中国文友,建立了深厚的友谊。这些人中有被胡适列举应该作传记的中国文化名人俞樾、张謇、严复、梁启超,屠寄、郑孝胥等。他们意气相投,诗文酬唱,书信往返,雅集宴饮,在中外文化交流史上写下了值得纪念的篇章。     

养精种玉汤对TA系菌株基因回变菌落影响的研究

目的:探讨养精种玉汤对TA97、TA98、TA100、TA102菌株基因回变菌落的影响,对其遗传安全性进行研究。方法:采用直接平皿掺入技术,设养精种玉汤不同剂量对TA97、TA98、TA100、TA102系列菌株进行体外染毒,观察其回复突变菌落增长状况。结果:在0.8~200.0mg/皿的不同测试浓度,+S9与-S9两种测试系统条件下,其作用的4种测试菌株的回变菌落数与溶剂对照相比均无明显增加,回变菌落背景正常,未显示其有抑菌作用,且无剂量-反应关系。结论:养精种玉汤药液在本试验所确定的200.0mg/皿剂量范围内,初步认为对TA系列测试菌株无明显致DNA碱基置换及移码突变性。     

张天文教授治疗呃逆经验

文章介绍张天文教授治疗呃逆的临床经验,张教授认为呃逆的病位在膈;病变的关键脏腑在胃,并与脾、肝、肺、肾密切相关;主要病机为膈间气机逆乱,胃气上逆动膈;人体以五脏为中心,五脏之间生理上相互协调,病理上相互影响,因此,治疗呃逆应当从整体观念与五脏辨证入手,“谨守病机,各司其属”,不应单纯见呃止呃,并且针药并举,各发其长。     

Neuroprotective effects of bloodletting atJing points combined with mild induced hypothermia in acute severe traumatic brain injury

Bloodletting at Jing points has been used to treat coma in traditional Chinese medicine. Mild induced hypothermia has also been shown to have neuroprotective effects. However, the therapeutic effects of bloodletting at Jing points and mild induced hypothermia alone are limited. Therefore, we investigated whether combined treatment might have clinical effectiveness for the treatment of acute severe traumatic brain injury. Using a rat model of traumatic brain injury, combined treatment substantially alleviated cerebral edema and bloodbrain barrier dysfunction. Furthermore, neurological function was ameliorated, and cellular necrosis and the inflammatory response were lessened. These findings suggest that the combined effects of bloodletting at Jing points(20 μL, twice a day, for 2 days) and mild induced hypothermia(6 hours) are better than their individual effects alone. Their combined application may have marked neuroprotective effects in the clinical treatment of acute severe traumatic brain injury.     

Establishment of a Quantitative Polymerase Chain Reaction Assay for Monitoring Chimeric Antigen Receptor T Cells in Peripheral Blood

Background

The chimeric antigen receptor (CAR) consists of an antigen recognition moiety from a monoclonal antibody fused to an intracellular signalling domain capable of activating T cells. The specific structure of the CAR molecule has been used in various basic research and clinical settings to detect CAR expression, but it is necessary to develop more specific and simpler monitoring methods to observe real-time changes.

Relationship between ADAMTS4 and carotid atherosclerotic plaque vulnerability in humans

Background

Rupture of atherosclerotic plaques and the resulting thrombosis are vital causes of clinical ischemic events. Recent studies have shown that ADAMTS4 (a disintegrin and metalloproteinase with thrombospondin motifs 4) is a pathogenic factor of plaque vulnerability in mice. However, the relationship between ADAMTS4 and carotid atherosclerotic vulnerable plaques in humans remains unclear.

“同气相求”理论内涵及其对中医基本理论的影响

目的：探讨＂同气相求＂理论内涵及其对中医基本理论的影响。方法：借助《说文解字》等工具书以明确＂同气相求＂的理论内涵,引述《易经》《尚书》等古代文献以探讨＂同气相求＂对中医基本理论的影响。结果：＂同气相求＂对阴阳五行学说在中医学中的应用进行了一定的补充和完善,并推动了中医推理方法的形成和发展。结论：＂同气相求＂影响着中医基本理论的形成和发展完善,使这些理论形成独特的体系而较全面的指导临床。     

《辅行诀》和《伤寒杂病论》“方同名异”及其原因解玄

目的：研究《辅行诀》与《伤寒杂病论》的渊源关系及二者＂方同名异＂之特点。方法：通过《辅行诀》与《伤寒杂病论》中有关药方及服药方法来论证。结果：《辅行诀》与《伤寒杂病论》同出一源——《汤液经法》。结论：发现《辅行诀》与《伤寒杂病论》存在＂方同名异＂这一特点,并从仲景＂避道家之称＂、汉时医家方剂命名法等方面解玄＂方同名异＂之谜。