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31.
通过对《外科证治全生集》与《洞天奥旨》的比较研究,发现二者在重视阴阳辨证治疗、力主内治,反对轻用外治,以及温药治疗阴证等方面有着相同的学术主张,二者存在学术渊源关系。《外科证治全生集》主要在阴疽的治疗上更具优势,《洞天奥旨》相关论述内容更早且更为丰富,见解较为合理。因此,就通常所论的外科全生派及力主内治的外科学派来说,不能忽视《洞天奥旨》的学术贡献,应该从外科学术流派的角度给予它更高的学术地位。 相似文献
32.
Jin Hong Lim Joon Seong Park Dong Sup Yoon 《HPB : the official journal of the International Hepato Pancreato Biliary Association》2017,19(5):388-395
Background
The clinical relevance of fibrosis with regard to tumor progression is supported by the correlation between fibrosis and poor outcomes. Fecal elastase-1 (FE-1) level has been used to assess exocrine dysfunction of the pancreas and to predict pancreas fibrosis. The aim of this study was to assess the impact of FE-1 on the survival of pancreatic cancer patients.Methods
Between January 2006 and December 2014, 136 patients with pancreatic adenocarcinoma underwent R0 resection at Gangnam Severance Hospital, Korea. Preoperative FE-1 levels were available in 94 patients who were enrolled in the study. Patients were classified into two groups according to preoperative FE-1: “normal” (≥200 μg/g) or “reduced” (<200 μg/g).Results
Median preoperative FE-1 level was 130.1 μg/g (IQR 32.0; 238.3). 62 patients (66.0%) had reduced pancreatic function and 32 patients (34.0%) had normal pancreatic function. The two groups had significantly different disease-free survival (P < 0.001). On multivariate analysis, normal FE-1, no lymph node metastasis and completion of adjuvant chemotherapy were found to be independent prognostic factors for better DFS (P = 0.001, P = 0.017, P = 0.038, respectively).Conclusion
FE-1 is a simple and non-invasive predictive clinical marker for prognosis of pancreatic cancer after attempted curative resection. 相似文献33.
目的观察电针董氏奇穴联合舒肛解郁止痛汤中药坐浴治疗功能性肛门直肠痛的临床疗效。方法将60例功能性肛门直肠痛患者采用随机数字表法分为对照组与治疗组各30例。对照组采用中药舒肛解郁止痛汤温水坐浴,治疗组在中药温水坐浴的基础上联合电针董氏奇穴中双侧"三其穴(其门、其角、其正)"、灵骨、大白、肠门。比较两组患者临床疗效、疼痛视觉模拟量表(VAS)评分、SF-36生活质量量表评分、焦虑自评量表(SAS)、抑郁自评量表(SDS)、肛门直肠测压及不良反应。结果治疗组临床总有效率为80.00%,显著高于对照组的50.00%(P<0.05);治疗后两组的VAS评分、SAS评分、SDS评分、肛门直肠测压评分均降低(P<0.05),SF-36生活质量量表评分均升高(P<0.05),且治疗后治疗组的VAS评分、SAS评分、SDS评分、肛门直肠测压评分低于对照组(P<0.05),SF-36生活质量量表评分高于对照组(P<0.05);两组患者均未出现明显不良反应。结论电针董氏奇穴联合舒肛解郁止痛汤中药坐浴治疗功能性肛门直肠痛疗效显著,可有效缓解疼痛和盆底高张力状态,能明显改善焦虑、抑郁等情绪,提高生活质量,且无不良反应。 相似文献
34.
目的 探讨侗族人群铅暴露与糖尿病前期、糖尿病的关联性。方法 通过分层多阶段抽样调查贵州省侗族30~79岁之间的居民共3 225人,采用问卷调查、体格检查采集居民健康状况并收集生物样本,电感耦合等离子体质谱法来检测调查对象尿铅浓度,采用非条件logistic回归分析尿铅(四分位数)与糖尿病前期、糖尿病患病风险的关联性。结果 贵州省侗族人群尿铅浓度为2.87 μg(1.33~4.83 μg),糖尿病患病率为9.02%(291/3 225人),糖尿病前期患病率为48.00%(1 548/3 225人),多因素校正后,尿铅浓度与糖尿病前期存在关联,尿铅浓度的第四分位与第一分位相比OR = 1.41(1.15,1.72),未发现尿铅浓度与糖尿病之间有明显关联性。结论 贵州省侗族人群中尿铅浓度的升高与糖尿病前期风险具有关联性,未发现尿铅浓度与糖尿病患病风险存在关联性。 相似文献
35.
批质量保证抽样法(LQAS)在街道儿童“四苗”覆盖率评价中的应用 总被引:1,自引:0,他引:1
应用批质量保证抽样法(LotQualityAssuranceSampling,LQAs),对南昌市东湘区四个街道(相当于乡镇三级单位)的儿童计划免疫“四苗”覆盖率进行了现场调查。结果显示,各街道“四苗”覆盖率均达到85%的水平,与按容量比例的概率抽样法(ProbabilityProportionaltoSize,PPS)结果相比较,无显著性差异,表明LQAS法可代替PPS法在三级单位进行儿童计划免疫工作评价,且经济、简便、快速、有效。 相似文献
36.
归蓉补血片对小鼠阴虚证模型作用的实验研究 总被引:8,自引:0,他引:8
目的:探讨归蓉补血片滋阴填精功效的药理作用。方法:观察该药对小鼠阴虚证模型的影响。结果:归蓉补血片组小鼠的体重净增和自主活动次数、低温游泳存活时间明显增加,血清超氧化物歧化酶活力增强、过氧化脂质含量降低。结论:该药对小鼠阴虚证模型有明显的改善作用,并能促进该模型血清SOD活力,抑制LPO的含量。 相似文献
37.
目的 调查贵州省黔东南州侗族女性胆结石的流行情况及影响因素,为预防女性胆结石的形成提供参考依据。方法 采用多阶段抽样方法调查黔东南州侗族30~79岁女性生殖特征、血脂水平和胆结石患病状况。采用卡方检验、非条件logistic回归分析探讨胆结石的影响因素。结果 侗族女性胆结石检出率为12.0%。随着年龄和BMI升高,胆结石发病呈逐渐上升趋势(P for trend<0.001)。离/退休人员、家庭主妇、行政/技术人员、大专及以上学历者是胆结石患病的高危人群(P<0.05)。绝经、糖尿病、避孕药服用、乳房肿块切除和血脂异常组胆结石检出率更高(P<0.05)。Logistic回归分析结果显示,对于绝经女性:家庭主妇、糖尿病、乳房肿块切除、LDL-C异常的OR(95%CI)分别为1.617(1.248~2.096)、1.690(1.077~2.652)、3.497(1.254~9.746)、1.287(1.008~1.643)。对未绝经女性:大专及以上学历、HDL-C异常者的OR(95%CI)分别为3.737(2.337~5.974)、2.355(1.104~5.026)。结论 绝经期女性、乳房肿块切除者、糖尿病和血脂异常者是胆结石发生的高危人群,为绝经期和非绝经期女性制定针对性预防策略有助于预防女性胆结石发生。 相似文献
38.
S. Liu G. Luo B. Sun J. Lu Q. Zu S. Yang X. Zhang J. Dong 《Transplantation proceedings》2017,49(2):297-302
Background
The optimal timing for stent removal after renal transplantation remains controversial. This article describes an interim analysis of a randomized, prospective, double-blind trial aimed at detecting differences in urological complications between early ureteral stent removal at 1 week and routine ureteral stent removal at 4 weeks.Methods
Between October 2010 and March 2015, 103 patients who underwent living donor renal transplantation at a single center were pre-operatively randomly assigned to the early ureteral stent removal (at 1 week) group or the routine ureteral stent removal (at 4 weeks) group. Urinary symptoms, auxiliary examination results, and obstruction events were recorded during 3 months of follow-up. A cost analysis of both the hospitalization and postoperative periods was discussed.Results
In total, 52 patients in the 1-week stent group and 51 patients in the 4-week stent group were analyzed. No serious adverse events were reported. Three episodes of urinary tract infections (UTIs) occurred in the 1-week stent group, and 18 such episodes were recorded in the 4-week stent group (5.8% vs 29.4%; P = .002). After adjusting for age, sex, ischemia time, renal artery number, body mass index, multiple arteries, and associated medical illness, regression analysis indicated that only stent duration was associated with UTI (OR, 8.791; 95% CI, 1.984–38.943; P = .004).Conclusions
The results of our study demonstrate that ureteral stent removal at 1 week reduces the risk of UTIs compared with routine removal at 4 weeks. Similar effects of ureteral stent removal on complication rates are observed for these two removal times. 相似文献39.
Zhixian Chen Han Zhong Guangfu Dong 《The American journal of the medical sciences》2019,357(6):461-467
BackgroundSystemic lupus erythematosus (SLE) patients often exhibit hematological abnormalities, but the role of thrombocytopenia on the prognosis of SLE shows inconsistent results. The purpose of this meta-analysis was to confirm the impact of thrombocytopenia on mortality and end organ damage in patients with SLE.Materials and MethodsThree electronic databases, PubMed, Embase and Cochrane library were systematically searched to identify the eligible studies from inception to November 2017 in order to evaluate the impact of thrombocytopenia on the prognosis of patients with SLE. The summary odds ratios (ORs) and 95% confidence intervals (CIs) were used to measure the impact of thrombocytopenia on mortality and end organ damage based on the random-effects model.ResultsA total of 8 studies that reported data on 2,158 patients with SLE were included. The summary OR indicated that SLE subjects with thrombocytopenia were significantly associated with an increased risk of mortality (OR: 4.57; 95% CI: 2.28-9.17; P < 0.001) and end-organ damage (OR: 3.31; 95% CI: 1.11-9.86; P = 0.031). Furthermore, the sensitivity analysis indicated stable mortality, while the result for end organ damage was variable. In addition, the patients with thrombocytopenia with disease duration <60 months presented a greater risk for mortality than those with disease duration ≥60.0 months (P = 0.002).ConclusionsPatients with SLE and thrombocytopenia were found to be associated with an increased risk of mortality and end organ damage. 相似文献
40.
目的:探讨桂蓉汤联合一体化方案对慢性肾脏病3~4期患者临床效果及对细胞免疫的影响。方法:选取2010年3月至2013年4月在本院中西医结合科进行住院治疗的慢性肾脏病3~4期患者92例,随机分为桂蓉汤组(n=46)和常规组(n=46),常规组给予患者慢性肾衰竭一体化治疗方法,桂蓉汤组在常规治疗措施基础上给予桂蓉汤联合一体化方案。分别于治疗前和治疗2个月时,检测血肌酐(SCr)和血尿素氮(BUN),随访后计算出相应的e GFR值,利用流式细胞仪对T细胞亚群CD4+,CD8+,CD4+/CD8+进行检测,采用放射免疫法对细胞因子白细胞介素-2(IL-2)和IL-6进行检测。结果:桂蓉汤组和常规组分别有39例(84.8%)和41例(89.1%)完成了治疗。桂蓉汤组患者总有效率53.8%,显著高于常规组的17.1%,差异具有统计学意义(P0.05);治疗2个月时,桂蓉汤组患者血SCr和BUN分别为(240.5±49.8)μmol·L-1和(9.8±3.9)mmol·L-1,均低于常规组,e GFR为(47.6±10.5)m L·(min·73 m2)-1,高于常规组,差异均具有统计学意义(P0.05);桂蓉汤组患者CD4+和CD4+/CD8+分别为(34.2±6.7)%和(1.6±0.2),均高于常规组,CD8+为(21.5±4.7)%,低于常规组,差异均具有统计学意义(P0.05),桂蓉汤组患者IL-2浓度为(19.6±6.3)mg·L-1,高于常规组,IL-6为(115.3±22.4)mg·L-1,低于常规组,差异均具有统计学意义(P0.05)。结论:桂蓉汤联合一体化方案应用于慢性肾脏病3~4期临床效果确切,能够有效改善肾功能,提高患者细胞免疫水平,有助于提高患者生存质量。 相似文献