| 侗族女性胆结石流行现况及其影响因素分析 |
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| 引用本文： | 聂婵,袁质平,杨婷婷,刘磊磊,彭莲,张林源,杨鋆,唐学杰,洪峰.侗族女性胆结石流行现况及其影响因素分析[J].现代预防医学,2021,0(19):3466-3470. |
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| 作者姓名： | 聂婵 袁质平 杨婷婷 刘磊磊 彭莲 张林源 杨鋆 唐学杰 洪峰 |
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| 作者单位： | 1. 贵州医科大学公共卫生学院环境污染与疾病监控教育部重点实验室，贵州 贵阳 550025；2. 贵州医科大学大学城医院；3. 贵阳市疾病预防控制中心 |
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| 摘 要： | 目的 调查贵州省黔东南州侗族女性胆结石的流行情况及影响因素，为预防女性胆结石的形成提供参考依据。方法 采用多阶段抽样方法调查黔东南州侗族30～79岁女性生殖特征、血脂水平和胆结石患病状况。采用卡方检验、非条件logistic回归分析探讨胆结石的影响因素。结果 侗族女性胆结石检出率为12.0%。随着年龄和BMI升高，胆结石发病呈逐渐上升趋势（P for trend<0.001）。离/退休人员、家庭主妇、行政/技术人员、大专及以上学历者是胆结石患病的高危人群（P<0.05）。绝经、糖尿病、避孕药服用、乳房肿块切除和血脂异常组胆结石检出率更高（P<0.05）。Logistic回归分析结果显示，对于绝经女性:家庭主妇、糖尿病、乳房肿块切除、LDL-C异常的OR（95%CI）分别为1.617（1.248~2.096）、1.690（1.077~2.652）、3.497（1.254~9.746）、1.287（1.008~1.643）。对未绝经女性:大专及以上学历、HDL-C异常者的OR（95%CI）分别为3.737（2.337~5.974）、2.355（1.104~5.026）。结论 绝经期女性、乳房肿块切除者、糖尿病和血脂异常者是胆结石发生的高危人群，为绝经期和非绝经期女性制定针对性预防策略有助于预防女性胆结石发生。
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| 关 键 词： | 侗族 胆结石 女性 危险因素 |
Prevalence and risk factors of gallstone disease among Dong women |
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| NIE Chan,YUAN Zhi-ping,YANG Ting-ting,LIU Lei-lei,PENG Lian,ZHANG Lin-yuan,YANG Yun,TANG Xue-jie,HONG Feng.Prevalence and risk factors of gallstone disease among Dong women[J].Modern Preventive Medicine,2021,0(19):3466-3470. |
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| Authors: | NIE Chan YUAN Zhi-ping YANG Ting-ting LIU Lei-lei PENG Lian ZHANG Lin-yuan YANG Yun TANG Xue-jie HONG Feng |
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| Affiliation: | *School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education， Guizhou Medical University, Guiyang, Guizhou 550025, China |
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| Abstract: | To investigate the prevalence of gallstones and its influencing factors among Dong women in Qiandongnan Prefecture of Guizhou Province and to provide reference for prevention of female gallstone formation. Methods Multi-stage sampling method was used to investigate the reproductive characteristics, prevalence of gallstones and blood lipid levels of 30-79-year-old females of Dong ethnic. Chi-square test and unconditional logistic regression analysis were used to explore the risk factors of gallstone. Results The detection rate of gallstone in Dong women was 12.0%. With the increase of age and BMI index, the incidence of gallstone gradually increased(P for trend<0.001). Retirees, housewives, administrative or technical personnel, and those with a college degree or above were the high-risk groups for gallstone disease(P<0.05). The incidence of gallstone was higher in menopausal, diabetes, contraceptive use, breast lump removal and dyslipidemia group(P<0.05). Logistic regression analysis showed that in the postmenopausal group, the OR(95%CI) of housewife, diabetes, breast lumpectomy, LDL-C abnormality were 1.617(1.248-2.096), 1.690(1.077-2.652), 3.497(1.254-9.746), 1.287(1.008-1.643), respectively. While in the premenopausal group, the OR(95%CI) of a college degree or above and abnormal HDL-C were 3.737(2.337-5.974) and 2.355(1.104-5.026), respectively. Conclusion Menopausal women, breast lumps removed, diabetes and dyslipidemia are at high risk of gallstone. The targeted prevention strategies for menopausal and non-menopausal women are meaningful to preventing the occurrence of gallstone in women. |
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| Keywords: | Dong ethnic Gallstone Women Risk factors |
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