湿热汤配合薄芝糖肽注射液治疗自身敏感性湿疹的临床观察

脾虚血燥型自身敏感性湿疹患者240例被随机分为治疗组和对照组。治疗组采用湿热汤配合薄芝糖肽注射液,对照组采用氯雷他啶片,临床验证其治疗3个月和1年时的总有效率及1年的痊愈率,治疗组分別为89.8%,82.5%,10.5%;对照组分別为60%,50%,1%,两组比较差异均有显著性（P〈0.01）。研究表明湿热汤配合薄芝糖肽注射液可抑制毛细血管通透性增加,具有良好的抗炎和抗迟发型变态反应和提高免疫的作用。     

Yo jyo hen shi ko, a novel Chinese herbal, prevents nonalcoholic steatohepatitis in ob/ob mice fed a high fat or methionine-choline-deficient diet.

BACKGROUND: Oxidative stress plays a role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Yo jyo hen shi ko (YHK) is a complex compound purported to reduce reactive oxygen species (ROS) by blocking the propagation of radical-induced reactions. The aim of this study was to evaluate the role of the effect of YHK in experimental NASH. METHODS: NASH was induced in male ob/ob mice by a high-fat (HF) diet or methionine/choline-deficient (MCD) diet for 4 weeks. YHK-treated animals received YHK solution orally (20 mg/kg/day) in both experimental diets (n=6; each group) while control animals received only vehicle. RESULTS: The MCD and HF groups developed moderate diffuse macrosteatosis, hepatocellular ballooning, and a diffuse inflammatory infiltrate. With the addition of YHK, there was a marked reduction in macrosteatosis in both groups. This was associated with decreased lipoperoxide and reduced glutathione-GSH concentrations as well as reduced serum aminotransferases and improved histological markers of inflammation. These changes were also associated with weight loss in the MCD+YHK group and diminished weight gain in the HF+YHK group. CONCLUSION: YHK therapy blunts the development of macrosteatosis in these models of NASH and significantly reduces markers of oxidative stress. YHK also diminishes weight gain in this obesity prone model. Our findings warrant further study on the mechanisms involved with these effects.     

《何氏虚劳心传》的用药规律分析

目的：分析《何氏虚劳心传》的用药规律,探讨虚劳的病机和治法特点。方法使用频数表对《何氏虚劳心传》治疗虚劳的21首方剂中所列药物的分类、使用频次、归经进行统计分析。结果虚劳的用药频次以补虚药最高,归经以肾膀胱经、肺大肠经、脾胃经为多。结论虚劳的基本病机在于阴虚,治疗注重补肾、健脾胃、生活调摄。     

秦艽清虚热的质疑与探析

质疑秦艽清虚热的功效。从秦艽功用沿革及历代医家对秦艽的认识,总结秦艽功效为主传尸骨蒸、除日晡潮热骨蒸、治小儿疳积骨蒸,而秦艽的除骨蒸作用不能等同于清虚热,秦艽并不具备治疗阴虚发热的特质,其在治疗阴虚发热方剂中的作用与其性用平和、辛散苦泄通利有关,而它本身并无直接的清退阴虚发热的功用。     

伤寒差后更发热及选方辨证探析

各医家对伤寒差后更发热原因的认识主要有:余热未尽、劳复、邪在少阳、重感于邪。对脉浮和脉沉实选用方剂的观点主要有:脉浮用枳实栀子豉汤,脉沉实者加大黄;脉浮用麻桂剂,脉沉实用承气剂;脉浮用柴胡桂枝汤,脉沉实用大柴胡汤。本文认为,伤寒差后更发热应为劳复使然,无明显表里症状者,用小柴胡汤和解之;如脉浮,为病后正气尚虚,重感于寒,可用柴胡桂枝汤微发汗解之;如脉沉实,为饮食失节,里有宿食,可用大柴胡汤下之。     

基于《黄帝内经》思想探析《饮食须知》的养生观

通过对《素问·脏气法时论》中"五谷为养,五果为助,五畜为益,五菜为充"的分析并结合元代养生家贾铭所撰《饮食须知》的论述,分析《饮食须知》中的食疗养生观,总结出《饮食须知》对于食物的选用十分考究,强调饮食禁忌,重视食物的寒热调和,不提倡生食、久食、多食的学术特色,以期更好地指导当代中国社会的养生。     

金实教授运用虫类药治疗类风湿关节炎经验

金实教授认为类风湿关节炎的病理因素紧扣风、寒、湿、热、痰、瘀六端,病理性质总属本虚标实,本虚主要为肝肾不足,气血亏虚,标实以风寒湿邪为主。金实教授认为本病病程较长,病久入络,易形成久痹、顽痹,而虫类药具有很好的搜剔病邪、剔络和络、通络止痛的作用,对类风湿关节炎有很好的治疗效果。现对金教授运用虫类药治疗类风湿关节炎进行经验汇总、分析。     

特色水药罐治疗颈型颈椎病临床观察

目的:以特色水药罐治疗颈型颈椎病为例,为临床提供一种更有效的拔罐方法。方法:将140例患者随机分为药罐组(47例)、水罐组(47例)、空罐组(46例)。药罐组将45℃的中药煎液倒入自制药罐内进行拔罐;水罐组将45℃水倒入自制药罐内进行拔罐;空罐组自制罐内不放任何东西进行常规拔罐。观察3组患者临床症状、体征,进行疗效比较。结果:药罐组临床治愈39例,显效8例;水罐组临床治愈20例,显效22例,有效5例;空罐组临床治愈12例,显效19例,有效15例。药罐组与水罐组不同疗效患者例数构成比及治疗前后疼痛积分差值进行比较,P<0.05;水罐组与空罐组比较,P<0.05;药罐组与空罐组比较,P<0.01。结论:特色药罐组疗效优于水罐组,水罐组疗效优于空罐组。     

针刺"下极泉"穴对中风后手指肌力的疗效观察

目的:寻找治疗中风后手指功能恢复的最佳方法。方法:将123例手指肌力为零级的中风患者随机分为观察组63例与对照组60例。对照组针刺曲池、手三里、外关等,观察组在对照组取穴基础上加取"下极泉"穴。治疗10次后评价疗效。结果:观察组的愈显率为74.6%,对照组为40.0%。经统计学分析,观察组疗效明显优于对照组(P<0.05)。结论:"下极泉"穴对手指肌力的引出有较好的疗效。     

胃黏膜异型增生虚实关联证数据库建立方法学探讨

对于慢性难治病的辨证论治，中医多采用虚实标本辨治的临床思维，辨析其虚实结构证候特征。以具有正邪相兼、虚实关联证候特征的胃黏膜异型增生（Dys）为范例，用数据库方法构建起Dys虚实关联证候结构辨识系统，探讨本病虚实关联证候结构的多态性特征及证候演变的动态性规律，从而从证候的虚实关联结构层次阐释辨证论治的机理。