全文获取类型
收费全文 | 7548篇 |
免费 | 318篇 |
国内免费 | 139篇 |
专业分类
耳鼻咽喉 | 47篇 |
儿科学 | 75篇 |
妇产科学 | 14篇 |
基础医学 | 752篇 |
口腔科学 | 338篇 |
临床医学 | 446篇 |
内科学 | 227篇 |
皮肤病学 | 40篇 |
神经病学 | 188篇 |
特种医学 | 375篇 |
外科学 | 2680篇 |
综合类 | 1510篇 |
预防医学 | 356篇 |
眼科学 | 39篇 |
药学 | 629篇 |
13篇 | |
中国医学 | 218篇 |
肿瘤学 | 58篇 |
出版年
2024年 | 14篇 |
2023年 | 105篇 |
2022年 | 182篇 |
2021年 | 292篇 |
2020年 | 282篇 |
2019年 | 216篇 |
2018年 | 199篇 |
2017年 | 230篇 |
2016年 | 326篇 |
2015年 | 282篇 |
2014年 | 646篇 |
2013年 | 553篇 |
2012年 | 620篇 |
2011年 | 649篇 |
2010年 | 522篇 |
2009年 | 409篇 |
2008年 | 334篇 |
2007年 | 313篇 |
2006年 | 310篇 |
2005年 | 252篇 |
2004年 | 200篇 |
2003年 | 153篇 |
2002年 | 124篇 |
2001年 | 100篇 |
2000年 | 84篇 |
1999年 | 63篇 |
1998年 | 45篇 |
1997年 | 57篇 |
1996年 | 51篇 |
1995年 | 44篇 |
1994年 | 37篇 |
1993年 | 34篇 |
1992年 | 32篇 |
1991年 | 28篇 |
1990年 | 21篇 |
1989年 | 19篇 |
1988年 | 31篇 |
1987年 | 24篇 |
1986年 | 15篇 |
1985年 | 17篇 |
1984年 | 16篇 |
1983年 | 16篇 |
1982年 | 13篇 |
1981年 | 12篇 |
1980年 | 5篇 |
1979年 | 6篇 |
1978年 | 6篇 |
1977年 | 6篇 |
1976年 | 2篇 |
1973年 | 4篇 |
排序方式: 共有8005条查询结果,搜索用时 15 毫秒
71.
72.
目的:建立测定生长激素(GH)在体生物活性的方法.方法:以去垂体大鼠体重增长(BWG)和胫骨骺软骨板宽度(TEW)为指标,观察动物性别、给药途径、次数和周期不同对效应的影响;同时进行4dBWG,6dBWG和6dTEW法,测定GH的效价(平行线3×3设计).结果:♀和♂sc和im给药以及每日给药1次和2次的BWG和TEW差异无显著意义.给药6d比给药4d引起较大的BWG和TEW(P<005).4dBWG法和6dBWG法在0020-0500IU·d-1有较好的λ值(00660和01747)和r值(09000和09237);4dBWG,6dBWG和6dTEW法测得rhGH的效价为46132,39829和48023IU/amp.6dBWG法有较小的λ值和较低的ARFL值.结论:可在同一组去垂体大鼠体内同时用4dBWG,6dBWG和6dTEW法测GH活性,以6dBWG法较好. 相似文献
73.
74.
目的 探讨平板运动试验及心向量对冠心病的诊断价值。方法 典型心绞痛64例,不典型心绞痛44例进行平板试验及心向量检查。结果 108例受检,冠状动脉造影正常42例,冠状动脉狭窄≥50%66例。两种方法检出冠心病的敏感性分别为81.8%和56.0%。结论 平板运动试验诊断冠心病的敏感性高于心向量,特别是对于右冠及双束支病变的冠心病患。 相似文献
75.
O. Zaha T. Hirata F. Kinjo A. Saito H. Fukuhara 《Journal of infection and chemotherapy》2002,8(1):94-98
We assessed the efficacy and adverse effects of ivermectin for the treatment of chronic strongyloidiasis. Fifty patients
were treated with a single dose of ivermectin at approximately 200 μg/kg, and the dose was repeated 2 weeks later. The eradication
rate was 96% (48 of 50 patients) at 2 weeks after the first dose and 98% at 2 weeks after the second dose (49 of 50 patients).
In the latter cases, no recurrence was noted at the end of the 4-month post-treatment follow-up period. The gastrointestinal
symptoms observed most frequently before the treatment were borborygmus, constipation, and diarrhea. These symptoms improved
in the majority of patients after the treatment. Side effects, including nausea and vomiting, occurred in 1 patient (2%),
but these were mild and transient. Although abnormal values in laboratory tests were observed in 4 patients (8%), they were
mild, and no particular clinical care was required. Thus, ivermectin showed an excellent antihelminthic effect, with little
toxicity. Our results indicate that a regimen of two single doses of 200 μg/kg ivermectin, given 2 weeks apart, is clinically
suitable for the treatment of chronic strongyloidiasis.
Received: April 25, 2001 / Accepted: November 16, 2001 相似文献
76.
In the developing spinal cord of the frog, Xenopus laevis, a population of interneurons assumes a pattern that represents a previously undescribed level of organization. Glyoxylic acid treatment and immunocytochemistry show that the neurons contain catecholamines and their synthetic enzyme, tyrosine hydroxylase. Cells are located within the ependymal layer of the floor plate region of the larval spinal cord. The cells have several processes including a long one that projects toward the brain without fasciculating with other labeled processes. In addition, the cytoplasm of the catecholaminergic cells extends into the central canal, showing that they are a population of cerebrospinal fluid-contacting neurons. The spatial domain of catecholaminergic neurons starts abruptly at the boundary between the hindbrain and spinal cord and continues to the tip of the tail. The neurons occupy two longitudinal columns within the sheet of floor plate cells, which includes cells that do not exhibit the catecholaminergic phenotype. Unlabeled cells are intercalated between catecholaminergic cells in each column, giving the labeled cells the appearance of being spaced along the length of the spinal cord. This general arrangement is evident at the time of hatching. Spatial analysis showed that the position of cells along a column is not random. The nonrandom behavior is due to cells being excluded from the area immediately surrounding other catecholaminergic cells. Further analysis showed that the cellular pattern lacks segmental or other periodic repeats. Ultimately, the location of a cell within a column depends upon the position of its closest catecholaminergic neighbor. © 1993 Wiley-Liss, Inc. 相似文献
77.
目的 比较改良尿道板重建卷管尿道成形术(又称Koyanagi术)与尿道板纵切卷管尿道成形术(TIP)在儿童尿道下裂中的临床疗效。方法 回顾性分析2018年1月—2021年10月甘肃省妇幼保健院收治的104例尿道下裂患儿的临床资料,其中53例患儿行改良Koyanagi术(研究组),51例患儿行TIP(对照组)。两组患儿术后均随访12个月。比较两组手术时间、术中出血量、术后疼痛及排尿功能、手术成功情况,对比两组术后并发症发生情况。结果 两组手术时间、术中出血量比较,差异均无统计学意义(P >0.05)。两组患儿术后4、12、24和48 h的FLACC评分比较,采用重复测量设计的方差分析,结果 ①不同时间点FLACC评分差异有统计学意义(F =10.871,P =0.000);②研究组与对照组FLACC评分差异无统计学意义(F =1.849,P =0.157);③研究组与对照组FLACC评分变化趋势差异无统计学意义(F =2.516,P =0.085)。两组患儿术后12个月的最大尿流率、平均尿流率、排尿量、尿流时间、手术成功率比较,差异均无统计学意义(P >0.05)。研究组术后总并发症发生率低于对照组(P <0.05)。结论 改良Koyanagi术与TIP治疗儿童尿道下裂疗效相近,均可获得满意效果,但改良Koyanagi术在降低术后并发症方面具有优势。 相似文献
78.
The distal femoral growth plate has a uniquely convoluted structure comprised of four mammillate processes. Factors contributing to the development of these processes and overall plate geometry were explored using three-dimensional image analysis of the canine distal femoral epiphysis. The growth plate at birth remains relatively flat until ossification of the epiphysis begins at 1 week of age. Epiphyseal ossification proceeds eccentrically, projecting in the medial-lateral and anterior-posterior directions. Growth plate activity indexed by [3H]thymidine labeling and plate thickness revealed regional differences in cell proliferation. This was measured as a decreased labeling index and thinning of the growth plate in areas capped by the ossifying epiphysis. The eccentric ossification pattern and associated variations in growth plate activity result in definition of an "intraphyseal" groove and medial-lateral oriented sulcus. The groove and sulcus bisect the plate into four quadrants, giving rise to a convoluted structure composed of four areas of plate elevations termed mammillary processes (MP). By 5 weeks, the pattern of ossification results in greater development of the MP in the anterior-medial quadrant and in decreasing order, in the posterior-medial, anterior, and posterior-lateral quadrants. By 10 weeks, a uniform rate of cell proliferation was observed coincident with completion of ossification of the epiphysis. The data suggest that localized variations in growth plate proliferation are associated with ossification of the epiphysis.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
79.
目的评估AO肩锁钢板钩治疗重型肩锁关节脱位的手术疗效.方法回顾性分析两年来27例手术病人的手术治疗和疗效.结果手术方法符合生理结构,手术时间平均30分钟,内固定牢靠.根据Murley和Constant[1]评分,优良率94%.结论 AO肩锁钢板钩治疗重型肩锁关节脱位,手术方法简单,疗效可靠,允许病人术后早期功能锻炼. 相似文献
80.