腹针加腕踝针治疗腰椎间盘突出症临床观察

目的观察腹针加腕踝针对腰椎间盘突出症疼痛及腰椎功能障碍的作用。方法将符合纳入标准的78例患者随机分为治疗组和对照组。治疗组45例采用腹针加腕踝针治疗,对照组33例采用常规体针治疗,分别观察治疗前及治疗1次、3次、1个疗程结束后视觉模拟评分（VAS）和中文版Oswestry腰椎功能障碍指数（ODI）的变化。结果治疗组治疗1次后VAS明显下降（P〈0.05）,而ODI下降无统计学意义（P〉0.05）;3次治疗及疗程结束后,两组VAS和ODI均有明显改善,且治疗组优于对照组。结论腹针加腕踝针治疗腰椎间盘突出症,能迅速有效地缓解疼痛,对改善腰椎功能也有很好的作用。     

Hcy、hs-CRP与IL-6在慢性肾功能不全患者中的应用

目的探讨慢性肾功能不全患者血清同型半胱氨酸（Hcy）,超敏C反应蛋白（hs—CRP）,白细胞介素6（IL-6）检测的临床意义。方法应用化学发光法、散射浊度法和酶联免疫吸附法分别测定40例慢性肾功能不全患者Hcy、Hs—CRP和IL-6水平,以40名正常人为对照组,进行t检验及线性相关分析。结果慢性肾功能不全组Hcy、Hs—CRP和IL6水平[分别为（20．9±58）mmol／L,（124±68）mg／L,（3769±257）ng／L]明显高于对照组[分别为（8．1±42）mmol／L,（2．4±09）mg／L,（782±153）ng／L]。从相关分析看,两组患者Hcy,hs—CRP,IL-6浓度随着尿素氮、肌酐浓度的增高而增高。结论慢性肾功能不全患者普遍存在高Hcy血症,hs—CRP,IL-6也明显升高,这几项指标的检测有助于判断患者病情的变化。     

星状神经节阻滞联合局部注射治疗颞下颌关节功能紊乱综合征30例临床报告

目的 观察星状神经节阻滞联合局部注射治疗颞下颌关节紊乱综合征的疗效.方法 选择症状典型患者60例,随机分为两组.A组为治疗组,星状神经节阻滞联合局部注射治疗.B组为对照组,采用电针针刺治疗.结果 A组治愈26例,有效3例,无效1例,治愈与有效率96.7%;B组治愈12例,有效9例,无效9例,治愈与有效率70%.结论 星状神经节阻滞联合局部注射治疗颞下颌关节紊乱综合征是一种较单纯电针针刺更有效的方法.     

海绵体内注射shIGFBP-3对糖尿病性勃起功能障碍大鼠勃起功能的影响

目的:观察海绵体内注射shIGFBP-3后大鼠阴茎海绵体内压和海绵体平滑肌密度的变化,评价其对大鼠糖尿病性勃起功能障碍的治疗效果.方法:30只SD大鼠随机分为3组,每组10只.造模成功后,各组分别海绵体内注射pGPU6/GFP/Neo shIGFBP-3,pGPU6/GFP/Neo-randomer shRNA和生理盐水.注射3个月后测量大鼠海绵体内压评价大鼠勃起功能,Masson法检测大鼠阴茎海绵体平滑肌密度的变化,Western blot检测阴茎海绵体中IGFBP-3蛋白的表达.结果:shIGFBP-3组大鼠海绵体内压为(112±16) mmHg,高于randomer shRNA组(63±11) mmHg和对照组(59±12) mmHg,差异有统计学意义(P＜0.05).与randomer shRNA组和对照组相比,shIGFBP-3组大鼠阴茎海绵体平滑肌的密度明显上升,差异均有统计学意义(P＜0.05);Western blot显示shIGFBP-3组中IGFBP-3蛋白表达较其他两组明显减少.结论:shIGFBP 3基因注射可能提高糖尿病性勃起功能障碍大鼠的阴茎海绵体内压及改善阴茎海绵体平滑肌的密度.     

难治性癫(癎)患者基本认知能力分析

目的 分析手术前难治性癫(癎)患者基本认知能力,为合理制定治疗方案提供参考依据.方法 对46例手术前难治性癫(癎)患者使用《基本认知能力测验》软件进行测评,测试结果进行统计学分析.结果 与常模组相比,难治性癫(癎)患者的认知功能广泛受损,包括数字鉴别[(10.0±5.0)分比(12.0±4.0)分]、汉字快速比较[(8.6±4.8)分比(12.0±4.0)分]、心算效率[(7.4±3.4)分比(12.0±4.0)分]、汉字旋转[(4.8±2.1)分比(12.0±4.0)分]、数字工作记忆[(8.6±3.6)分比(12.0 ±4.0)分]和双字词再认[(10.0±3.5)分比(12.0±4.0)分]、无意义图形再认[(7.1±4.3)分比(12.0±4.0)分],差异均具有统计学意义(均P＜0.01).结论 难治性癫(癎)病患者的基本认知能力明显低于常模组.重视难治性癫(癎)患者基本认知能力状况,对评估手术疗效、患者愈后和提高患者生活质量具有重要意义.     

结合PNF的关节松动术(MWP)技术治疗肘关节功能障碍初探

目的:利用结合神经肌肉促进技术(PNF)的关节松动术(Mobilization with PNF,MWP)技术治疗肘关节骨折术后功能障碍,探讨其对关节主/被动活动度、疼痛、肌肉力量和本体感觉的影响。方法:取2009年8月～2012年4月本院肘关节骨折术后功能障碍患者共32例。患者术后病情稳定,视内固定牢固程度开始康复训练。分为实验组和对照组,对照组患者先常规治疗、关节松动技术、关节牵伸治疗和一般性肌力训练。实验组在以上治疗中,追加MWP治疗替换关节松动术,分别治疗8周后进行功能评价。结果:治疗前后对比,实验组、对照组在关节活动度、视觉模拟(VAS)评分、各肌群肌力方面有明显差异(P<0.01),实验组在位置觉、被动运动觉上有明显差异(P<0.01);治疗后,实验组与对照组在关节活动度、伸肌肌力和旋前肌力上有明显差异(P<0.05),尤其是在屈曲角度、主动旋前角度、VAS评分、位置觉、被动运动觉上差异明显(P<0.01)。结论:MWP对肘关节功能障碍治疗有明显疗效,对肘关节主/被动关节活动度、肌肉力量、本体感觉和疼痛缓解都有促进作用,并优于单纯使用关节松动技术的传统治疗方法。     

A Case of Cardiac Dysfunction Associated with Monoclonal Gammopathy of Undetermined Significance

The monoclonal gammopathies (MG) are monoclonal neoplasms related to each other by virtue of their development from common progenitors in the B lymphocyte lineage. Cardiac dysfunction in patients with MG is not well established. We experienced a case of cardiac dysfunction associated with MG identified by echocardiography and biopsy. Fifty nine year-old man was admitted because of dyspnea for several months. Echocardiography revealed diastolic dysfunction showing restrictive physiology with elevated left ventricular filling pressure. Bone marrow (BM) studies and immunoelectrophoresis were compatible with monoclonal gammopathy of undetermined significance. Endomyocardial, BM, and enteral biopsies for ruling out for amyloidosis (Congo-red stain) were negative. This is the case of non-amyloidotic light chain deposition cardiomyopathy.     

四磨汤口服液对胃肠运动功能障碍模型大鼠胃残留、小肠推进率及结肠P物质的影响

目的：观察四磨汤口服液对胃肠运动功能障碍模型大鼠胃残留率、小肠推进率及结肠P物质（SP）的影响．方法：6f）只大鼠随机分为空白组,模型组,四磨汤口服液高、中、低剂量组以及西药组,按夹尾法配合饥饱失常法造模后给予相应药物灌胃,检测半固体营养糊在体内的胃残留率和小肠推进率,按免疫组化要求染色并观察sP的阳性面积。结果：与空白组比较,模型组大鼠胃残留率明显升高以及小肠推进率显著降低（P〈0．05）;四磨汤口服液高剂量组较模型组大鼠胃残留率降低、小肠推进率增加（P〈0．05）;模型组结肠SP表达水平较空白组显著降低（P〈0.05）;四磨汤口服液高剂量组与西药组结肠SP阳性表达均较模型组增高（P〈0．05）。结论：夹尾法配合不规则喂养可导致大鼠胃肠运动紊乱,四磨汤口服液能促进胃肠运动障碍模型大鼠胃肠蠕动功能的恢复,能够增高胃肠功能障碍大鼠兴奋性神经递质SP的表达,可能是其调整胃肠运动功能障碍的作用机制之一。     

Prevalence of Signs of Temporomandibular Joint Dysfunction in Asymptomatic Edentulous Subjects: A Cross-Sectional Study

Patients having complete dentures with reduced vertical dimension generally do not manifest Temporomandibular Joint problems. It is not understood as to why the closure of jaws in dentulous individuals can predispose to Temporomandibular Joint problems, while the same etiology in edentulous subjects does not cause any concern. This study was planned to find out the prevalence of various Temporomandibular Joint dysfunction signs in subjects who were edentulous for a period of 6 months to 2 year. The various signs were obtained from a population of 100 healthy asymptomatic edentulous subjects by a questionnaire and then were clinically examined for the presence or absence of signs of Temporomandibular Joint dysfunction. 59% of the subjects exhibited one or more signs of Temporomandibular Joint dysfunction, 41% of the subjects did not show any signs of Temporomandibular Joint dysfunction. 56.6% of males reported signs of Temporomandibular Joint dysfunction when compared with females which was 62.5%. 43.3% of males did not show any signs of Temporomandibular Joint dysfunction when compared with those of the females which was 37.5%. The number of subjects who showed two signs was 29%, subjects who had only one sign was 25%. It was found that dysfunction was prevalent among both men and women in more than half of the asymptomatic subjects examined. 59% had one or as many as three signs of Temporomandibular dysfunction. The most commonly seen Joint dysfunction was the joint sounds which was 47%     

多器官功能障碍综合征防治研究进展

本研究以综述的形式讨论目前MODS诊断、发病机制和治疗领域的某些研究进展。