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《Seminars in arthritis and rheumatism》2016,45(6):666-671
ObjectiveTo better understand why immunosuppressed individuals with systemic lupus erythematosus (SLE) fail to receive influenza and pneumococcal vaccines.MethodsThese cross-sectional data were derived from the 2009 cycle of the Lupus Outcomes Study (LOS), an annual longitudinal telephone survey of individuals with confirmed SLE. Respondents were included in the analysis if they had taken immunosuppressive medications in the past year. We assessed any prior receipt of pneumococcal vaccine and influenza vaccine in the past year, and then elicited reasons for not receiving vaccination. We used bivariate statistics and multivariate logistic regression to assess frequency and predictors of reported reasons for not obtaining influenza or pneumococcal vaccines.ResultsAmong 508 respondents who received immunosuppressants, 485 reported whether they had received vaccines. Among the 175 respondents who did not receive an influenza vaccine, the most common reason was lack of doctor recommendation (55%), followed by efficacy or safety concerns (21%), and lack of time (19%). Reasons for not receiving pneumococcal vaccine (N = 159) were similar: lack of recommendation (87%), lack of time (7%), and efficacy or safety concerns (4%). Younger, less-educated, non-white patients with shorter disease duration, as well as those immunosuppressed with steroids alone, were at the greatest risk for not receiving indicated vaccine recommendations.ConclusionsThe most common reason why individuals with SLE did not receive pneumococcal and influenza vaccines was that physicians failed to recommend them. Data suggest that increasing vaccination rates in SLE will require improved process quality at the provider level, as well as addressing patient concerns and barriers. 相似文献
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对一起尿源性脓毒血症患者死亡案例进行解析,从明确诊断标准、制定规范举措、畅通绿色通道、促进患方参与等方面进行改进。改进后,尿源性脓毒血症患者诊断率提高,就诊至处理时间(DTN)从88.9min缩短至55.6min(P<0.001),患者住院时间由7.9天缩短至4.9天,人均住院总费用减少8 105元,差异均有统计学意义(P<0.05)。运用精益管理方法,优化专科急危重症诊治流程,能够缩短治疗时间,促进患者康复,节约住院费用,改善患者愈后 相似文献
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《International Journal of Orthopaedic and Trauma Nursing》2014,18(1):23-34
BackgroundA high prevalence for the development of delirium after hip fracture was found in the group of geriatric patients. The National Institute for Health and Clinical Excellence has introduced a guideline for the management delirium (NICE, 2010). Protocols composed of detection, prevention and management of post-operative delirium required some adaptation to meet the needs of local nurses.AimA protocol with a nursing care plan referenced from an international guideline and other literature was developed to predict, prevent and manage post-operative delirium for geriatric patients with hip fracture.MethodsThe literature suggests numerous risk factors are associated with post-operative delirium and its preventive interventions were adopted to develop the protocol and nursing care plan.FindingsSix major risk categories included mental and behavioural influence, sensory impairment, physiological influence, immobility influence, electrolyte disturbance and infection influence. These were used for screening patients, accompanied by various preventive interventions. A protocol was developed to strive for the best management of geriatric patients receiving hip fracture surgery from admission to discharge.ConclusionsThe protocol incorporated with the Risk Assessment for Management of Postoperative delirium (RAMP) care plan was adapted for staff to implement in their local clinical area. Further study is required to determine its effectiveness on the prevention of the development of post operative delirium (POD) in the future. 相似文献
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目的探讨谷氨酸在偏头痛中发病机制的作用及水平变化。方法抽选珠海市平沙医院门诊或者住院诊断为偏头痛患者60例,随机分组分为预防性药物治疗组(应用西比灵治疗)和常规药物治疗组,各30例。同时选择60例健康人员作为对照组,不进行任何药物治疗。测量所选对象体内血清谷氨酸水平,比较偏头痛及对照正常组患者用药前及用药后8 w血浆中谷氨酸水平及用药前后头痛发作时间。同时对比治疗组两种方法治疗后患者头痛发作频率。结果药物使用前,治疗组患者谷氨酸水平为(235.6±25.6)μmol/L,明显高于对照组,P<0.01;治疗后8 w,治疗组谷氨酸水平明显下降,与对照组比较,P>0.05;治疗后,预防性药物治疗组患者谷氨酸水平明显降低,发作频率明显减少,与对照组相比,P<0.05。结论偏头痛患者血清内谷氨酸水平明显提高,预防性药物明显能够降低谷氨酸水平,降低头痛发作频率。 相似文献
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Answer questions and earn CME/CNE After a comprehensive review of the evidence, the United States Preventive Services Task Force recently endorsed screening with low‐dose computed tomography as an early detection approach that has the potential to significantly reduce deaths due to lung cancer. Prudent implementation of lung cancer screening as a high‐quality preventive health service is a complex challenge. The clinical evaluation and management of high‐risk cohorts in the absence of symptoms mandates an approach that differs significantly from that of symptom‐detected lung cancer. As with other cancer screenings, it is essential to provide to informed at‐risk individuals a safe, high‐quality, cost‐effective, and accessible service. In this review, the components of a successful screening program are discussed as we begin to disseminate lung cancer screening as a national resource to improve outcomes with this lethal cancer. This information about lung cancer screening will assist clinicians with communications about the potential benefits and harms of this service for high‐risk individuals considering participation in the screening process. CA Cancer J Clin 2014;64:351–363. © 2014 American Cancer Society. 相似文献
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目的 分析门诊输液护理差错发生的原因,并提出防范对策.方法 回顾性分析2011年5月~2014年5月本院门诊输液室发生26例护理差错的资料.结果 护理差错类型包括医嘱转抄错误、注射错误及液体外渗等,护理差错主要发生在白班,工作年限5年内护士护理差错的发生率高于其他工作年限的护士(P<0.05).结论 未严格执行“三查七对”是发生差错的重要原因.科学管理、完善各项规章制度是预防门诊输液护理差错的主要对策. 相似文献