全文获取类型
收费全文 | 7684篇 |
免费 | 907篇 |
国内免费 | 139篇 |
专业分类
耳鼻咽喉 | 43篇 |
儿科学 | 110篇 |
妇产科学 | 62篇 |
基础医学 | 753篇 |
口腔科学 | 87篇 |
临床医学 | 930篇 |
内科学 | 813篇 |
皮肤病学 | 31篇 |
神经病学 | 1614篇 |
特种医学 | 504篇 |
外科学 | 457篇 |
综合类 | 1171篇 |
一般理论 | 2篇 |
预防医学 | 768篇 |
眼科学 | 63篇 |
药学 | 692篇 |
8篇 | |
中国医学 | 487篇 |
肿瘤学 | 135篇 |
出版年
2024年 | 12篇 |
2023年 | 116篇 |
2022年 | 194篇 |
2021年 | 414篇 |
2020年 | 392篇 |
2019年 | 358篇 |
2018年 | 318篇 |
2017年 | 344篇 |
2016年 | 330篇 |
2015年 | 358篇 |
2014年 | 620篇 |
2013年 | 549篇 |
2012年 | 482篇 |
2011年 | 511篇 |
2010年 | 379篇 |
2009年 | 375篇 |
2008年 | 329篇 |
2007年 | 328篇 |
2006年 | 310篇 |
2005年 | 263篇 |
2004年 | 207篇 |
2003年 | 202篇 |
2002年 | 162篇 |
2001年 | 124篇 |
2000年 | 93篇 |
1999年 | 96篇 |
1998年 | 63篇 |
1997年 | 74篇 |
1996年 | 48篇 |
1995年 | 56篇 |
1994年 | 62篇 |
1993年 | 53篇 |
1992年 | 39篇 |
1991年 | 47篇 |
1990年 | 58篇 |
1989年 | 36篇 |
1988年 | 31篇 |
1987年 | 28篇 |
1986年 | 30篇 |
1985年 | 37篇 |
1984年 | 38篇 |
1983年 | 15篇 |
1982年 | 22篇 |
1981年 | 19篇 |
1980年 | 25篇 |
1979年 | 15篇 |
1978年 | 16篇 |
1977年 | 22篇 |
1975年 | 8篇 |
1974年 | 7篇 |
排序方式: 共有8730条查询结果,搜索用时 203 毫秒
81.
82.
在聚合物固体电解质(聚乙二醇不饱和聚酯网络-LiClO4)中进行吡咯聚合原位制得了聚吡咯/聚合物固体电解质双层复合膜。用扫描电镜观察复合膜的界面结构,用循环伏安和交流阻抗法研究了复合膜的电化学杂脱掺杂性能。结果表明,聚吡咯/聚合物固体电解质双层复合膜具有相互穿插渗透的固/固密接界面结构,这种界面结构改善了聚吡咯和聚俣物固体电解质间的界面接触,提高了聚吡咯在聚俣物固体电解质中的电化学掺杂脱掺杂性能。 相似文献
83.
The gold-standard method for diagnosing arteriogenic erectile dysfunction (AED) is the penile Doppler ultrasonography. We proposed a novel method for predicting AED using ultrasonic shear wave elastography (SWE) considering that the former was invasive and variable. A total of 98 male patients were enrolled in our study, referred for ED between December 2018 and October 2020. For comparison, we also included 42 volunteers from the Healthy Physical Examination Center of our hospital. The Penile Doppler Ultrasonography (PDU) and SWE were performed for all patients with the intracavernosal injection (ICI). We named three groups as AED group, nonvascular ED group and healthy controls group. No statistically significant differences were found among the three groups in terms of demographic and clinical characteristics. There were no significant differences in IIEF-5 between AED and nonvascular ED. A significant (r = 0.642, p < 0.0001) positive correlation between flaccid and erectile SWE was observed. With a cut-off value of 13.45 KPa, the area under curve, specificity, and sensitivity of the SWE values under the flaccid state in distinguishing AED from healthy subjects were 0.867, 0.786 and 0.896 respectively. The SWE value in the flaccid state can distinguish the AED from healthy subjects. 相似文献
84.
Elbow arthrodesis is uncommon and is usually performed as a salvage procedure to provide a stable elbow. There is a significant gap in the literature about the indications, contraindications, fusion angle, technical tips, and reversibility of the procedure. This review addresses these questions in a evidence based manner, based on the published literature. 相似文献
85.
86.
87.
择业期间大学生焦虑水平及其影响因素 总被引:16,自引:0,他引:16
目的 :对择业期间大学生焦虑水平及其影响因素进行调查 ,为高校心理卫生工作提供科学依据。方法 :采用“状态—特质焦虑量表”对 5 2 2名大学生择业期间焦虑水平进行测查 ,采用问卷调查法及访谈法探讨影响择业期间大学生焦虑水平的因素。结果 :择业情境导致大学生焦虑水平普遍升高 ,部分学生呈过度焦虑状态。择业期间大学生焦虑水平受自身条件、个人理想、社会环境、学校教育、家庭期望等因素的综合影响 ,其中自身条件、个人理想为首要因素。结论 :择业期间大学生产生焦虑的根本原因在于职业理想与实现可能的矛盾冲突 相似文献
88.
89.
Summary We studied the membrane effects of (1S,2S)-2-(2-[[3-2(benzimidazolyl) propyllmethylamino]ethyl)-6-fluoro-1,2,3,4-tetrahydro-l-isopropyl-2-naphthyl-methoxy-acetate dihydrochloride, Ro 40-5967, a new non-dihydropyridine (DHP) Ca2+ channel antagonist, on dog coronary and saphenous arterial vascular muscle cells using the whole-cell patch-clamp method. Long-lasting (L-type) inward currents in 20 mM Ba2+ were measured over a range of test potentials (300 ms) from –50 mV to + 90 mV from a holding potential of –80 mV in the presence of 1 M Bay k8644 (a DHP Ca2+ agonist). Ro 40-5967 caused a concentration-dependent suppression of Ca2+ channel currents in muscle cells from both arteries, with greater potency on coronary than saphenous arterial cells. The concentration of Ro 40-5967 which inhibited the magnitude of peak inward currents by 50% (IC50) was estimated to be 1 M (n = 5) in muscle cells from coronary artery and 10 M (n = 4) in saphenous artery. Ro 40-5967 (1 M) decreased the amplitude of the activation current-voltage relationship for coronary L-type Ca2+ channel currents over a wider range of membrane potentials than verapamil, diltiazem, or nifedipine. In contrast, block of Ca2+ channel currents in saphenous artery cells by 1 M Ro 40-5967 was only observed at command potentials positive to 0 mV. Ro 40-5967 (1 M) significantly shifted the voltage-inactivation curve downward by 40% in coronary (n = 4), but only by 18% in saphenous arterial muscle cells (n = 3). The non-parallel shift of the coronary artery inactivation curve suggests that pronounced resting channel block is a notable feature of Ro 40-5967. The marked inhibition of Ba2+ current by 1 M Ro 40-5967 in the inactivation protocol in coronary arterial muscle cells was found over the entire range of membrane holding potentials tested, while inhibition in the saphenous artery inactivation curve occurred only from holding potentials more positive than –40 mV. Therefore, Ro 40-5967 is unique: 1) in acting over a wider range of voltages, on both instantaneous and resting Ca2+ currents, than other Ca2+ antagonists; 2) in producing more significant resting state block; and 3) in acting with selectivity for coronary over saphenous arteries.This research was supported by National Institutes of Health grants HL38537, HL38645, and by F. Hoffmann-La Roche, Basel, Switzerland 相似文献
90.
The experimental hepatic cirrhosis was induced either by bile duct ligation (BDL) or by pretreatment with dimethylnitrosamine
(DMNA). The pharmacokinetics of theophylline were studied after a single intravenous or a single oral administration. Using
the ultrafiltration method, protein-drug binding experiments were also carried out. The bilirubin level was several-fold increased
by BDL, but not by DMNA treatment. The albumin content was decreased in both cirrhotic groups. The total clearance (Clt, ml/kg/hr)
of theophylline in both hepatic cirrhosis groups significantly decreased and the terminal half-life (t1/2) in the cirrhotic rats was increased about two-fold after intravenous and oral administration. The volume of distribution
at steady state (Vdss, ml/kg) was increased slightly in the cirrhotic groups. Protein binding in BDL (8.67±4.85%) decreased
about four-folds, but in DMNA (73.00±9.85%) similar result, was observed as compared with the control. Increased free fraction
of theophylline did not increase the volume of distribution in BDL. Therefore decreased total body clearance of theophylline
was mainly due to decreased intrinsic clearance of theophylline in the liver. The absolute bioavailability of theophylline
in these experiments was between 63.8 and 72.8%(66.1% in BDL, 63.8% in Sham operated and Control, 72.8% in DMNA). These results
suggest that in the experimental hepatic cirrhosis model, administration route does not affect the disposition of theophylline. 相似文献