Elaprase 关键词：亨特氏综合征

英国Shire生物制药公司用于治疗亨特氏综合征（Hunter syndrome）的人类酶替代疗法药物——Elaprase（idursulfase）日前在墨西哥获得了上市批准。墨西哥是世界上第十大药物市场，同时也是第一个批准了Elaprase的拉丁美洲国家。     

闲适的澳洲VS疯狂的拉美

返璞归真和趣味性是澳洲人休闲健身的主题，而拉丁美洲人却总爱为自己的健身运动涂抹上浓浓的冒险色彩。大千世界的养生健身方式是无奇不有，也无处不在，只要能够有益身心，提高生命质量，又何妨借鉴？     

中国医疗器械在拉丁美洲兰国的进出口分析

拉丁美洲的市场,是中国医疗器械进出口很重要的市场.对中国诊断医疗产品在巴西,墨西哥和阿根廷市场的进出口分析会对中国产品进入这一市场提供理论和实践的参考依据.北美自由贸易协议和政府采购对墨两哥的市场影响很大.巴西和阿根廷的当地医疗器械制造商较弱,进入壁垒适中,中国产品有较大的竞争优势.     

世界制药工业面临的新挑战

一、全球药品销售额增长趋缓 据Graham Lewis等人的报道，2004年全球药品销售额的增长速度有所减慢，这种趋势在很大程度上取决于美国：迅速发展的生物技术工业为未来展现出希望：整个拉丁美洲、亚洲和小欧洲的市场确是增长强劲的一年。     

Gastroenterology training in Latin America

Latin America is characterized by ethnic, geographical, cultural, and economic diversity; therefore, training in gastroenterology in the region must be considered in this context. The continent’s medical education is characterized by a lack of standards and the volume of research continues to be relatively small. There is a multiplicity of events in general gastroenterology and in sub-disciplines, both at regional and local levels, which ensure that many colleagues have access to information. Medical educat...     

Human papilloma virus and esophageal carcinoma in a Latin-American region

AIM： To investigate the presence of high-risk human papilloma virus （HPV） in esophageal squamous cell carcinomas （ESCCs） in a non-selected Mexican population. METHODS： Cases with a pathological diagnosis of squamous cell carcinoma of the esophagus were obtained from Department of Pathology files, at the National Cancer Institute in Mexico City during the period between 2000 and 2008. Slides from each case were reviewed and cases with sufficient neoplastic tissue were selected for molecular analysis. DNA was extracted from paraffin-embedded tissue samples for polymerase chain reaction analysis to detect HPV DNA sequences. Demographic and clinical data of each patient were retrieved from corresponding clinical records. RESULTS： HPV was detected in 15 （25%） of ESCCs. HPV-16 was the most frequently observed genotype, followed by HPV-18; HPV-59 was also detected in one case. Unfortunately, HPV genotype could not be established in three cases due to lack of material for direct sequencing, although universal primers detected the presence of HPV generic sequences. No low-risk HPV genotypes were found nor was HPV-16/18 co- infection. HPV presence in ESCC was not significantly associated with gender, age, alcohol consumption, smoking, anatomic location, or histologic grade. All patients belonged to low and very low socioeconomic strata, and were diagnosed at advanced disease stage. Male patients were most commonly affected and the male：female ratio in HPV-positive ESCC increased two- fold in comparison with HPV-negative cases （6.5：1 vs 3/1：1）. CONCLUSION： High prevalence of high-risk HPV in ESCC in Mexico does not support the hypothesis that HPV-associated ESCC is more common in areas with higher ESCC incidence rates.     

登革热候选疫苗Ⅲ期临床研究效力达80%

在Ⅲ期临床试验TIDES中,日本武田制药公司的登革热疫苗tak-003使感染和住院病例数分别减少了80%和95%。在拉丁美洲和亚洲的登革热流行国家,共有20000名4~16岁的志愿者按2:1的比例分别接受2剂tak-003或安慰剂免疫,疫苗的有效率为70%?98%。     

Lack of sexual knowledge blamed for HIV/AIDS among Latin American youths

Lack of sexual knowledge is the main culprit for HIV/AIDS among Latin American youths, said Chilean expert Raquel Child, who also blamed the authorities for not doing enough to help youngsters deal with the deadly disease.