缺血型视网膜中央静脉阻塞的氪离子激光治疗

目的 探讨缺血型视网膜中央静脉阻塞的氪离子激光治疗的疗效.方法 回顾性分析我院应用氪激光全视网膜光凝治疗的缺血型中央静脉阻塞102眼的临床资料.结果 102眼缺血型视网膜中央静脉阻塞中73眼有效,占71.56%;27眼好转,占26.47%;2眼因玻璃体出血,继发新生血管性青光眼或并发白内障失明而无效,占1.97%.结论 对于缺血型视网膜中央静脉阻塞的患者应尽早实行全视网膜光凝术治疗,确保有效光斑的总数与密度是全视网膜光凝术成功的关键.     

中心性浆液性脉络膜视网膜病变的中西医研究现状

作者综述了近年来中心性浆液性脉络膜视网膜病变在病因、病机、治疗方面的研究现状以及中医药治疗本病的最新进展。     

ADHD患儿伴不同程度感觉统合失调影响因素分析

目的研究注意缺陷多动障碍（Attention Deficit Hyperactivity Disorder，ADHD）患儿的感觉统合失调率及不同程度感觉统合失调的影响因素。方法采用儿童感觉统合能力发展评定量表和自拟儿童生长发育及家庭环境因素调查表对儿科神经专科门诊ADHD患儿进行感觉统合能力评定和影响因素分析，同时采用Rutter儿童行为评定量表、瑞文测验联合型（Combined Raven’s Test，CRT）了解患儿的行为问题和智力情况。结果ADHD患儿的感觉统台失调率为98．26％，且以中重度为多（占83，68％），单因素分析表明，感觉统合失调程度主要影响因素与儿童学习成绩，智商，伙伴关系，母亲文化程度，家庭气氛等有关。结论ADHD惠儿的感觉统合失调发生率较高，且失调程度是多因素相互作用的结果。     

女孩特发性中枢性性早熟的早期识别与防治

特发性中枢性性早熟是女孩常见的一种内分泌疾病,女孩特发性中枢性性早熟在早期可以通过观察第二性征的发育变化以及临床检查、GnRHa激发实验等措施加以识别;性早熟的预防可以采取减少饮食中激素的摄入、保持营养平衡、进行适度的运动等方法;女孩特发性中枢性性早熟可以用西药、中药或中西药结合进行治疗。     

中西医学数据整合框架实现的意义和前景

随着现代诊疗技术的发展、医院信息系统的建成及大型医疗仪器的采用,医院每日产生大量的医学数据。中医行业如何充分利用这些医学数据所蕴含的信息,对于提升中医医疗水平和发展中医学术有着极为重要的现实意义。参照国际医学数据传输标准HL7,通过建立医学数据中心,利用现代先进的计算机技术构建中西医学数据整合框架体系,为中西医学数据整合、数据挖掘提供一个可靠的数据平台。     

Central nervous system involvement following diagnosis of non-Hodgkin's lymphoma: a risk model.

BACKGROUND: To determine the incidence and risk factors for central nervous system (CNS) relapse in patients with non-Hodgkin's lymphoma (NHL). PATIENTS AND METHODS: Patient records were registered prospectively in successive patients with NHL admitted to the Norwegian Radium Hospital from 1980 to 1996. A total of 2514 patients had no CNS involvement at diagnosis and were treated according to standard protocols. The incidence and risk factors for CNS progression or relapse were examined retrospectively. RESULTS: In low-grade (L)-NHL, the risk of CNS involvement was low (2.8%). In high-grade (H)-NHL, lymphoblastic and Burkitt's NHL patients had a high risk of CNS recurrence (24.4%) at 5 years, and prophylaxis seemed to reduce this risk. For the other patients with H-NHL, the proportion with CNS involvement at 5 years was 5.2%. Multivariate analysis identified five independent risk factors, each present in >5% of patients: elevated serum lactate dehydrogenase, serum albumin <35 g/l, <60 years of age, retroperitoneal lymph node involvement and involvement of more than one extranodal site. If four or five of these risk factors were present, the risk of CNS recurrence was in excess of 25% at 5 years. CONCLUSIONS: The risk of CNS involvement in this study is comparable with the results from other large series. CNS prophylaxis is not recommended in any subgroup of L-NHL. The risk of CNS involvement among patients with either Burkitt's or lymphoblastic lymphomas is considerable and these patients should therefore receive intensive chemotherapy including systemic and intrathecal methotrexate. Patients with other types of H-NHL should receive adequate CNS prophylaxis if at least four of the five risk factors identified are present.     

中医现代化方法学研究

本文从方法学研究的角度，提出1．现代中医“四诊”多维信息集成诊断智能系统的目标与发展思路，重点任务为：新型传感染手段的应用研究，人体生理信号处理方法研究，机体功能状态特征信息提取方法研究；2．功能性检测在中医诊断中应用研究的目标与发展思路，重点任务为：应用人体功能检测技术开展中医证候与人体内在功能变化的关联性研究，以及中医四诊指征与人体内在功能变化的关联性研究，研制有中医特色的人体功能检测仪器。     

Quality of life in patients after meningioma resection

OBJECTIVES: To evaluate quality of life in patients after tumour resection, to assess different dimensions of quality of life, to compare a newly designed questionnaire with the Nottingham Health Profile. SUBJECTIVE: A non-selected neurosurgically treated series of patients with meningiomas was investigated with reference to quality of life as a judgement of one's own needs and concerns and subjective disease dependent perception. METHODS: A postal survey was sent out to 155 patients who underwent resection of a meningioma between 1977 and 1993 at our clinic. The survey consisted of the specifically designed "Innsbruck Health Dimensions Questionnaire for Neurosurgical Patients" IHD(NS) and the Nottingham Health Profile NHP. The data were put into categories and analysed statistically (Chi-square, Mann Whitney U, Kruaskal-Wallis H-tests). RESULTS: 82 patients (53 female, 29 male) responded (response rate 59%). 10 had died and 7 had moved. The majority of patients (50/61% on NHP and 49/59.7% on IHD) had mild to moderate impairment of quality of life. 20% of the patients showed moderate to severe impairment of the dimensions: physical handicap and energy level. Physical impairment correlated to tumour size. This group was characterised by mainly belonging to the over 70ies age group and taking anti-epileptics. CONCLUSIONS: The quality of life impairments in most patients after tumour resection can be classified as mild to moderate. However, other disease and age effects are difficult to distinguish without a control group. The IHD(NS) correlated well with the NHP questionnaire.     

Ultrasonographic detection of very thin percutaneous central venous catheter in neonates

To assess the ability of ultrasonography to detect the tip of a very thin (0.4 mm outer diameter) percutaneous central venous catheter (PCVC) in neonates, the PCVC tip location was assessed by ultrasonography (US) and compared to the location estimated by standard radiography for 57 PCVCs in 44 neonates. Of 57 occasions, the examiner could not find the PCVC tip in three cases (5%). In the remaining 54 instances, in 87% of cases, the PCVC tip position was consistent with the location implied by skeletal landmarks on standard radiographs. On 24 occasions we also assessed catheter tip dislodgement according to flexion and extension of the infant's arm. US could detect 78% of cases of catheter tip dislodgement. The PCVC tip was sometimes visualized as a dot and parallel lines as well as mere parallel lines. In a large population of cases, US is a reliable method for detection of a thin PCVC tip. US provides precise information about the PCVC tip position in relation to vascular structure and contributes to safer positioning of the PCVC than traditional radiography alone.