全文获取类型
收费全文 | 10113篇 |
免费 | 1782篇 |
国内免费 | 145篇 |
专业分类
耳鼻咽喉 | 29篇 |
儿科学 | 184篇 |
妇产科学 | 37篇 |
基础医学 | 2120篇 |
口腔科学 | 251篇 |
临床医学 | 1048篇 |
内科学 | 1148篇 |
皮肤病学 | 73篇 |
神经病学 | 573篇 |
特种医学 | 368篇 |
外科学 | 2845篇 |
综合类 | 1077篇 |
预防医学 | 506篇 |
眼科学 | 80篇 |
药学 | 619篇 |
中国医学 | 653篇 |
肿瘤学 | 429篇 |
出版年
2024年 | 47篇 |
2023年 | 277篇 |
2022年 | 442篇 |
2021年 | 417篇 |
2020年 | 372篇 |
2019年 | 856篇 |
2018年 | 1298篇 |
2017年 | 259篇 |
2016年 | 263篇 |
2015年 | 237篇 |
2014年 | 755篇 |
2013年 | 679篇 |
2012年 | 416篇 |
2011年 | 480篇 |
2010年 | 338篇 |
2009年 | 389篇 |
2008年 | 304篇 |
2007年 | 260篇 |
2006年 | 224篇 |
2005年 | 394篇 |
2004年 | 236篇 |
2003年 | 157篇 |
2002年 | 142篇 |
2001年 | 101篇 |
2000年 | 309篇 |
1999年 | 286篇 |
1998年 | 311篇 |
1997年 | 168篇 |
1996年 | 147篇 |
1995年 | 111篇 |
1994年 | 150篇 |
1993年 | 174篇 |
1992年 | 246篇 |
1991年 | 68篇 |
1990年 | 162篇 |
1989年 | 45篇 |
1988年 | 123篇 |
1987年 | 84篇 |
1986年 | 61篇 |
1985年 | 62篇 |
1984年 | 55篇 |
1983年 | 22篇 |
1982年 | 41篇 |
1981年 | 7篇 |
1980年 | 10篇 |
1979年 | 9篇 |
1978年 | 5篇 |
1977年 | 6篇 |
1976年 | 11篇 |
1974年 | 11篇 |
排序方式: 共有10000条查询结果,搜索用时 46 毫秒
11.
肠易激综合征(Irritable bowel syndrome,IBS)是临床常见病、多发病,其治疗方法丰富,但部分患者疗效欠佳,发展成难治性IBS。目前国内外关于针灸治疗难治性IBS的临床随机对照试验尚不多见。本文立足试验方案设计的“PICOS”原则,从研究对象及诊断标准、干预措施、对照措施、结局指标四个方面入手,重点探讨针刺辅助治疗难治性肠易激综合征临床试验设计的关键要点。从选择特色优势病种、明确诊断标准、制定符合临床实际的干预方案、运用符合目标的安慰针刺、结合研究设计和目的选定结局指标几个角度,阐述试验相关环节设计的原因和思考。 相似文献
12.
《Best Practice & Research: Clinical Rheumatology》2022,36(4):101810
Osteoarthritis (OA) is a highly prevalent joint disease that is associated with pain, loss of function, and high direct and indirect economic costs. The current therapeutic options are inadequate, providing only a moderate symptom relief without the possibility of disease modification. While treatment options and personalized medicines are increasing for many complex diseases, OA drug development has been impeded by the advanced state of disease at the time of diagnosis and intervention, heterogeneity in both symptoms and rates of progression, and a lack of validated biomarkers and relevant outcome measures. This review article summarizes the OA landscape, including therapies in development as potential OA treatments, potential biomarkers undergoing evaluation by the US Food and Drug Administration, and a summary of current OA treatment guidelines, with a particular focus on the knee OA. 相似文献
13.
Determinants of Tobacco Use among Children of a Rural Village in India: An Exploratory Qualitative Study 下载免费PDF全文
Akanksha GoyalAshish SharmaSunita AgarwalSuman BhansaliKumar Gaurav ChhabraChaya Chhabra 《Asian Pacific journal of cancer prevention》2020,21(1):81-86
Background: Tobacco is one of the leading causes of preventable deaths. It is both a major social and health problem. According to National Sample Survey Organization of Government of India about 20 million children of ages 10-14 are estimated to be tobacco-addicted. There are grave consequences of tobacco both socially and also on health thus it is of utmost importance to understand the factors leading to its use and to plan strategies to reduce its intake. However, the health implications of this social issue in a rural context have not been explored. Aims and Objective: this study makes an attempt to explore the health and social implications of tobacco usage by the children below the age of 14 years in hamlet. Materials and Methods: The present study employed a qualitative study design. Data was collected using focus group discussion and in-depth interview of key informants. Thematic analysis for exploring the explicit and implicit meanings within the data was done. The themes which emerged were knowledge about tobacco and the various products available, children and parents’ tobacco use and habits, the health and social implication of tobacco use, reasons for tobacco use by the children. Results: It was found tobacco use by the children was very common in the community. Parent, peer pressure, sibling pressure were found to be playing important role in the initiation of tobacco habit by the child. Further illiteracy and lack of awareness was also lead to tobacco use among children. Conclusion: The study identifies education and awareness of parents about the ill-effects of tobacco play an important role as parents act as role model for their children, thus equal stress should be laid in improving the parental habits. Even raising the prices of tobacco products can help in controlling this habit. 相似文献
14.
15.
16.
17.
18.
C. R. Irwin T. Myrillas M. Smyth J. Doogan C. Rice S. L. Schor 《Journal of oral pathology & medicine》1998,27(6):255-259
Fibroblasts incorporated within collagen gels induce a cell-mediated contraction of the gel to form a three-dimensional, tissue-like structure by a mechanism thought to mimic wound contraction in vivo . In this study a gel contraction model was used to investigate the ability of fibroblasts derived from adult gingiva, adult skin and fetal skin to organise a collagen matrix. In addition the effects of interleukin-1β (IL-1β) on the contraction process was also investigated. Over the concentration range 5-50 U/ml, IL-1β induced a statistically significant inhibition of gel contraction in all fibroblast cell types ( P <0.05), although fetal fibroblasts appeared least responsive and gingival fibroblasts most responsive to the inhibitory effects of this cytokine. Comparison of gel contraction by the different fibroblast strains indicated that fetal and gingival fibroblasts shared similar contraction kinetics. For the adult skin fibroblasts, three of five strains studied showed significantly diminished levels of gel contraction compared to fetal and gingival cells. This apparent difference in fibroblast phenotype may, at least in part, explain the fetal-like wound healing pattern seen in the oral mucosa. 相似文献
19.
A new range of stand magnifiers has been released by the COIL company in the United Kingdom. Examination of these magnifiers reveals that they fail to deliver the rated magnifications labelled prominently on the appliances, as a result of the manufacturer's conformance with the requirements of the German DIN standard and the use of back vertex power (F'v) rather than equivalent dioptric power (Fm) of the magnifier. In this study we provide information on the optometric parameters of these new stand magnifiers that will assist the more accurate specification of improvements in vision expected from their use. 相似文献
20.
他汀类药物对心血管的保护作用 总被引:6,自引:0,他引:6
他汀类药物(statins)被研制出来的最初目的是降低血脂,但是现在发现它不仅具有降低血脂的作用,还具有很多其他的作用包括改善内皮细胞功能的紊乱,提高内皮源性一氧化氮合成酶的生物活性,抑制血管平滑肌细胞的增殖,抗氧化作用,抗炎作用,降低血压,逆转心血管系统的重构。充分理解statins的多效性作用及机制有利于它更好的在临床中被应用于心血管系统的预防和治疗。 相似文献