缺碘地区正常儿童的智力问题

本文使用《中国比内测验》测查缺碘地区正常学龄儿童智力状况,发现他们平均智商非常显著低于对照组(非缺碘地区)。同时应用精神运动功能试验、电测听仪检测发现还存在神经系统的轻微损伤。     

亚临床肝性脑病的早期诊断研究

目的:探讨亚临床肝性脑病(SHE)早期诊断的可靠、敏感方法。方法:对63例肝硬化失代偿期住院患者,临床上无肝性脑病的症状体征,均在住院3 d内进行智力测验,脑电图诱发电位检测。结果:智力测验异常率57.1%(36/63),脑电图异常率61.9%(39/63),诱发电位异常率74.6%(47/63)。结论:智力测验,脑电图,诱发电位检查为早期诊断亚临床肝性脑病的可靠、敏感方法。     

画钟测验在社区老年痴呆筛查中的应用

目的 评价画钟测验（CDT）在社区老年痴呆筛查中的应用价值.方法 在宣武区社区居民健康体检管理档案中,随机抽取60岁及以上老年痴呆者68例,同时随机抽取60岁及以上社区健康老年人76例,两组患者年龄性别匹配良好.对入组者逐一进行了CDT检查.结果 痴呆组CDT异常率为92.6%,与健康对照组差异有统计学意义（P＜0.01）;CDT评分在痴呆组与健康对照组之间差异有统计学意义（P＜0.01）（OR 1.46,95%CI 1.23～1.68）.结论 CDT适用于在社区老年痴呆筛查中应用.     

2007年西藏自治区碘缺乏病高危地区重点人群调查分析

Objective To propose prevention and control strategy against iodine deficiency disorders to prevent new cases of endemic cretinism from occurring. Methods In April and August 2007, all the suspected cretinism patients born after the first of January, 1997 were searched for in 16 counties from Lhasa, Shannan, Nyingchi, Qamdo and Xigaze. Meanwhile, 60 children aged 8-10 years were selected in each of the two rural villages of each county chosen. Goiter was examined using palpation and B-ultrasound, urinary iodine was determined, inteligence quotient(IQ) was tested; 30 women of childbearing age from each village chosen underwent urinary iodine test and household salt semi-quantitative detection. Results No new cases of endemic cretinism had been found; Palpation identified goiter at 4.5% (257/5680) in children, B-ultrasound revealed a rate of 4.7% (258/5433). Median of urinary iodine was 159.4 μg/L, the averaged IQ was 78.3±14.5; women of childbearing age had a median urinary iodine of 70.2 μg/L. The coverage rate of iodized salt was 52.8%. Conclusions Goiter rate in children, urinary iodine level meet the standard set for the elimination of iodine deficiency disorders; however, the low IQ children, low coverage of iodized salt and the level of urinary iodine in women of childbearing age are less than desirable. Iodine deficiency disorders prevention and control need to be strengthened.     

智商测定结果与临床诊断的一致性分析

智商(IQ)在精神发育迟滞的诊断中具有重要意义,是诊断本病的重要指标之一。但在智力测验过程中,受试者出于利益驱动,在检查过程中不合作,或故意伪装,有意装坏,将会使智测结果不准确,严重影响疾病的诊断。因此,在做出疾病诊断前应更多地了解患者的社会适应能力状况,尽可能多地收     

新疆阿克苏地区重点人群碘营养和智力水平调查

Objective To investigate the iodine nutritional status of school children, lactating women and infants in iodine deficient areas of Baicheng and Wushi Counties in Xinjiang Autonomous Region. Methods According to the geographic location of east, south, west and north of county, 10 primary schools of 8 townships were selected. In each school, 10 children among each gender and age group from 8 to 10 years old were selected. A total of 300 school children were chosen. One hundred and four infants aged 0-2 years old and their mother were selected in 8 townships. Iodine content in edible salt at household level, the urinary iodine in school children and lactating women, total goiter rate(TGR) and the status of the intelligence quotient (1Q) of school children, the status of psychological development of infants were observed. Direct titration assay for testing the salt iodine, colorimetric ceric-arsenic assay and vitriolic ammonium assimilation were used for testing urinary iodine. The size of thyroid gland was measured by palpation. The Combined Raven Test for Chinese Rural was used to test the IQ. The psychological development of infants was tested by Danver Development Screening Test (DDST). Results The coverage rate of iodized salt at household level was 73.1% (123/182), however, the proportion of households using adequately iodized salt was 64.1% (118/182). The medium of urinary iodine in school children was 103.7 μ/L, with 47.8%(75/157) less than 100 μg/L and 28.0% (44/157) less than 50 μg/L; it was 123.0 μg/L in Baieheng County, with 44.4%(28/63) less than 100 μg/L and 33.3%(21/63) less than 50 μg/L; it was 100.3 μg/L in Wushi County, 50.0%(47/94) less than 100 μg/L and 24.5%(23/94) less than 50 μg/L. The medium of urinary iodine in locating women was 143.3 μg/L, it was 119.7 μg/L and 184.6 μg/L in Baicheng and Wushi Counties, respectively. The total rate of goiter in school children was 14.3%(43/300), it was 10.8%(13/120) and 16.6%(30/180) in Baicheng and Wushi Counties, respectively. The average IQ in school children was 80.6±11.6, it was 83.0±11.6 and 79.0±11.7 in Baicheng and Wushi Counties, respectively. The proportion of mental retardation in school children (IQ≤69) was 13.0% (39/300), it was 6.7% (8/120) and 17.2%(31/180) in Baicheng and Wushi Counties, respectively. In addition, the proportion of psychological development in infants being normal, suspicious and abnormal was 78.8%(82/104), 12.5% (13/104) and 8.7%(9/104), respectively. Conclusion This study confirms the fact that there is also existence of mental retardation in children and infants, caused by iodine deficiency.     

韦氏成人智力测试全套与简式版本临床应用的比较

国内修订版本韦氏成人智力测试量表（WAIS-RC）在临床、司法鉴定、心理学界及教育界等领域得到广泛运用,具有良好的信度和效度.全套量表共由11大项目组成,完成测试需要75 min.近年来,国外学者首先选取部分测验组合成不同的简式量表进行临床应用研究,龚耀先等研究出WAIS-RC二合一至六合一的简式量表,并报告所有简式量表在正常国人中测评均有较好的效度.国内开发出简式韦氏成人智力测验量表,具有节约时间和人员等优点,但临床中发现该测试IQ结果似高于WAIS-RC的IQ值,本研究试图对两种测试方式的等值性作初步探讨,为临床应用和研究选择测试方式提供有关依据.     

联合型瑞文智力测验的应用研究

目的评价联合型瑞文智力测验的可靠性和有效性。方法应用韦氏量表和联合型瑞文测验分别进行个体和团体测验。结果两种智力测验方法存在较好的相关性,相关系数为0．71,对个体智力发育等级评定结果的符合率达78．8％。结论联合型瑞文智力测验能较好地反映受试儿童的智力发育情况,可以推广应用。     

胎儿窘迫对新生儿神经行为的影响及其预后的初步研究

目的测定宫内窘迫的新生儿神经行为及其幼儿期的智能发育,以探讨宫内窘迫与新生儿神经行为表现和预后的关系。方法新生儿期用新生儿神经行为２０项指标测定,２岁时用改良的韦克斯勒量表测定其智力发育。结果宫内窘迫新生儿６０例（窘迫组）与正常新生儿６０例（对照组）比较,测定总分之间差异有极显著性（Ｐ＜０．０１）,窘迫组中４１例无窒息者与对照组比较,差异有显著性（Ｐ＜０．０５）,窘迫组中１９例有窒息者与对照组差异更为显著（Ｐ＜０．００１）,急性窘迫３８例与慢性窘迫２２例之间也有显著差异（Ｐ＜０．０１）。幼儿２岁时智力测试显示,３８例急性窘迫儿与对照组无统计学差异,而２２例慢性窘迫儿与对照组相比差异有显著性（Ｐ＜０．０１）。结论胎儿窘迫可影响新生儿的神经行为能力,对幼儿期的智力发育也有一定影响,尤以慢性宫内缺氧为著