最大似然法和方根法计算HLA三座位单体型频率的比较

目的研究在不同样本量条件下,方根法和最大似然法计算HLA-A-B-DR三座位单体型的准确性。方法选择100例有家系资料的个体,以方根法和最大似然法分别计算其单体型频率,并与家系分析结果相比较。从四川骨髓库中选择8 933例无关个体,比较2种方法计算得到的单体型频率。结果在标本量分别为100例和8933例时,2种方法得到的最常见单体型分布差异无统计学意义。方根法计算结果中有大量单体型频率为负值,频率为正的单体型累计频率>1。结论总体来说,最大似然法比方根法更加准确,但2种算法得到的最常见单体型频率差异无统计学意义。     

Dance as a Therapy for Cancer Prevention

Even though the field of medicine has developed tremendously, the wide variety of cancer is still among chronic ‍and life threatening disease today. Therefore, the specialists constantly research and try every possible way to find ‍cure or preventive ways to stop its further development. For this reason, studies concerning the chronic disease such ‍as cancer have been spread to many different fields. In this regard, many other alternative ways besides medicine, ‍are used in prevention of cancer. Nutritional therapy, herbal therapy, sportive activities, art therapy, music therapy, ‍dance therapy, imagery, yoga and acupuncture can be given as examples. Among these, dance/movement therapy ‍which deals with individuals’ physical, emotional, cognitive as well as social integration is widely used as a popular ‍form of physical activity. ‍The physical benefits of dance therapy as exercise are well documented. Studies have shown that physical activity ‍is known to increase special neurotransmitter substances in the brain (endorphins), which create a state of wellbeing. ‍And total body movement such as dance enhances the functions of other body systems, such as circulatory, ‍respiratory, skeletal, and muscular systems. ‍Regarding its unique connection to the field of medicine, many researches have been undertaken on the effects of ‍dance/movement therapy in special settings with physical problems such as amputations, traumatic brain injury, ‍and stroke, chronic illnesses such as anorexia, bulimia, cancer, Alzheimer’s disease, cystic fibrosis, heart disease, ‍diabetes, asthma, AIDS, and arthritis. ‍Today dance/movement therapy is a well recognized form of complementary therapy used in hospitals as well as ‍at the comprehensive clinical cancer centres.     

Efficacy of dance-based paradigms,wearable sensors,and auditory feedback for gait retraining in children: A feasibility study

BackgroundDifferent feedback modes such as auditory, visual and haptic have been used in the past for gait retraining or learning movement patterns. The primary goal of this study was to investigate whether real time auditory feedback would be effective in children learning novel, dance-based movement patterns. For this purpose, a prototype wearable sensor was developed to provide auditory feedback whenever a child touches their heel to the ground.MethodsTo test the effectiveness of the auditory feedback in learning new patterns, typically developing children were taught simple Indian dance protocols consisting of four counts of foot-work which involved alternating heel-toe movements. The effect of wearing the sensor was assessed by the maximum vertical force with which the subjects struck their foot on the plate.ResultsAuditory feedback reduced the learning time and increased the number of correct movement patterns for trial duration of 2 min. The prototype device did not alter the maximum force with which the subject placed the foot on the ground.ConclusionsReal time auditory feedback can be reliably used to learn novel movement patterns.     

舞蹈活动改善儿童认知功能的系统综述

目的 系统综述舞蹈对儿童认知功能的干预效果,梳理儿童舞蹈干预方案设计的影响因素。     

双侧颧骨及下颌角截骨整形术矫正方脸畸形

目的　探讨矫正方脸畸形的一种新术式。方法　针对方脸畸形多表现为颧骨突出合并下颌角肥大的特点 ,采用双侧颧骨截骨降低加双侧下颌角截骨整形术 ,1次或分 2次手术完成矫治 ,操作完全在口内进行。结果　本组 2 1例 ,其中 1 2例为 1次手术完成 ,9例为分 2次手术完成。术后中面部宽度 (双侧颧点间距 )减少 (1 5 .3± 3.2 )mm ,下面部宽度 (双侧下颌角间距 )减少 (1 4 .2± 2 .5 )mm。伤口均愈合良好 ,无感染、血肿等并发症发生。仅 1例术后下唇麻木 ,1个月后自行恢复。术后 3个月以上复查 ,全部受术者外观改善均满意。结论　双侧颧骨及下颌角截骨术可有效降低面中 1 / 3宽度、突度及面下 1 / 3宽度 ,从而使整个面部轮廓变得圆滑、柔美 ,方形面型得到满意改善。     

广场舞对绝经期后骨质疏松患者的骨密度和骨转换指标影响的研究

目的观察广场舞对绝经后骨质疏松患者的骨密度、骨转换指标的影响。方法研究组:口服钙尔奇D600 mg每日1次的同时,联合广场舞运动方法干预,每周5次,每次平均0.5~1.0小时;对照组:单纯采用口服钙尔奇D600 mg每日1次,观察两组实验前及实验干预6个月后受试者骨密度、骨转换指标变化、骨痛。结果 (1)骨密度变化:研究组治疗6个月后,腰椎L2-4、股骨颈部的骨密度较治疗前明显升高(P0.05),Ward’s区骨密度无显著性改变。而对照组各部位骨密度较前无明显改变(P0.05)。(2)血生化中血钙、血磷及碱性磷酸酶指标值:两组生化指标在治疗前后无统计学差异(P0.05);治疗6个月后P1NP的水平明显升高(P0.05),β-CTX水平未有明显改变(P0.05)。(3)疼痛程度改善情况:两组治疗前后疼痛分级比较,研究组疼痛明显改善。结论广场舞运动能部分改善绝经后妇女骨密度,并且可以缓解骨质疏松引起的疼痛,是一种切实可行的预防和治疗骨质疏松症的临床方案。     

广场舞结合钙尔奇对绝经后妇女骨密度、血清性激素及平衡能力的影响

目的通过观察广场舞对绝经后妇女骨密度、血清性激素及平衡能力的影响,探讨广场舞防治绝经后妇女骨质疏松症、降低跌倒风险的作用。方法 80名绝经后妇女随机分为实验组和对照组,实验组应用广场舞运动联合钙剂干预,对照组单纯予以钙剂干预。实验前及实验干预后3个月和6个月分别检测两组受试者胫骨及足跟骨密度、血清性激素、睁眼和闭眼状态下单腿站立时间(TIME-SLC,TIME-SLO)、足底压力中心在左右和前后方向的最大位移量(D x,D y)。结果实验组治疗3个月及6个月后胫骨及足跟骨骨密度明显增加,与对照组比较有有显著性差异(P0.05);血清雌二醇(E_2)、孕酮(P)水平明显提高,与对照组比较有有显著性差异(P0.05);睁眼和闭眼状态下的单腿站立时间明显增加,与对照组比较有有显著性差异(P0.05);而TIME-SLC,TIME-SLO及Dx,Dy明显下降,具有显著性差异(P0.05)。结论广场舞运动结合钙剂能有效减缓绝经后妇女胫骨及足跟骨密度下降速度,提高血清性激素水平,改善平衡能力,且随着干预时间延长,效果更明显。     

音乐舞蹈对精神分裂症康复的影响

目的 了解音乐舞蹈对精神分裂症患者的康复作用。方法 应用BPRS、SANS、住院精神病人康复评定量表进行评估。结果 音乐舞蹈可以激活病人情绪、改善病人行为、提高病人主动性及改善病人的阴性症状。结论 音乐舞蹈是精神分裂症患者疾病康复的手段。