Cardiorespiratory complications after laparoscopic hernia repair in term and preterm babies

Purpose

The aim of this study was to clarify the incidence of postoperative complications in infants undergoing laparoscopic hernia repair within the first six months of life.

Methods

Retrospective, single-institution study comparing term and preterm babies undergoing surgery between March 2005 and September 2012. The charts were reviewed for postoperative complications and pre-existing diseases.

Results

In the term group 188 of 199 babies (94.5%) had an uneventful postoperative course. Eleven patients (5.5%) presented postoperative complications, three of them (1.5%) developed severe respiratory complications. A relation between pre-existing diseases and postoperative complications could be identified in two patients. Laparoscopy possibly induced cardiorespiratory instability in one infant.In the preterm group 109 of 137 babies (79.6%) had an uneventful postoperative course. 28 preterm infants (20.4%) developed postoperative complications, seven of them (5.1%) presented severe respiratory complications. Pre-existing diseases were identified as an influencing factor in 22 preterm infants. In one patient laparoscopy possibly caused minor instability of a pre-existing cardiac anomaly.

Conclusions

Postoperative complications are low in both groups, although the incidence is increased in preterm infants. Pre-existing diseases are a major influencing factor for preterm infants. In very few infants laparoscopy may have induced instability of cardiac anomalies.     

Characterization of poly-4-hydroxybutyrate mesh for hernia repair applications

Background

Phasix mesh is a fully resorbable implant for soft tissue reconstruction made from knitted poly-4-hydroxybutyrate monofilament fibers. The objectives of this study were to characterize the in vitro and in vivo mechanical and resorption properties of Phasix mesh over time, and to assess the functional performance in a porcine model of abdominal hernia repair.

Materials and methods

We evaluated accelerated in vitro degradation of Phasix mesh in 3 mol/L HCl through 120 h incubation. We also evaluated functional performance after repair of a surgically created abdominal hernia defect in a porcine model through 72 wk. Mechanical and molecular weight (MW) properties were fully characterized in both studies over time.

Results

Phasix mesh demonstrated a significant reduction in mechanical strength and MW over 120 h in the accelerated degradation in vitro test. In vivo, the Phasix mesh repair demonstrated 80%, 65%, 58%, 37%, and 18% greater strength, compared with native abdominal wall at 8, 16, 32, and 48 wk post-implantation, respectively, and comparable repair strength at 72 wk post-implantation despite a significant reduction in mesh MW over time.

Conclusions

Both in vitro and in vivo data suggest that Phasix mesh provides a durable scaffold for mechanical reinforcement of soft tissue. Furthermore, a Phasix mesh surgical defect repair in a large animal model demonstrated successful transfer of load bearing from the mesh to the repaired abdominal wall, thereby successfully returning the mechanical properties of repaired host tissue to its native state over an extended time period.     

Development of an animal model to investigate optimal laparoscopic trocar site fascial closure

Background

The rate of hernia formation after closure of 10–12 mm laparoscopic trocar sites is grossly under-reported. Using an animal model, we have developed a method to assess trocar site fascial dehiscence and the strength of different methods of fascial closure.

Materials and methods

Pigs (n = 9; 17 ± 2.5 lbs) underwent placement of 12 mm Hasson trocars with pneumoperitoneum maintained for 1 h. Three closure techniques (Figure-of-eight; simple interrupted; pulley) were compared with no fascial closure and to native fascia at five randomly allocated abdominal wall midline locations. Necropsy was performed on the fourth postoperative d. Statistical comparisons of tensile strength and breaking strength based on closure type and trocar location were made using ANOVA with Tukey’s tests.

Results

The mean (SD) force (Newtons) required for fascial disruption varied significantly with closure type [Native Fascia 170 (39), Figure-of-eight 169 (31), Pulley 167 (59), Simple Interrupted 151 (27), No Closure 108 (28)]; P = 0.007. The mean force required for fascial disruption was significantly increased for Native Fascia, Figure-of-eight, and Pulley relative to No Closure (P = 0.013, P = 0.015, P = 0.023, respectively). The mean (SD) force (in Newtons) required for fascial disruption also varied significantly with location of trocar [subxiphoid 181 (43), supraumbilical 151 (23), Umbilical 146 (23), infraumbilical 168 (62), suprapubic 120 (38)]; P = 0.03. The mean force for subxiphoid location was significantly increased relative to the suprapubic location (P = 0.021).

Conclusions

We have developed a novel assessment model that reliably detects differences in fascial integrity after laparoscopic trocar placement and closure. This model will allow for further testing of various trocars and closure techniques, and facilitate hernia prevention strategies.     

腹腔镜免钉合经腹部分腹膜外网片植入术与经腹腹膜前修补术的疗效比较

目的:对比分析腹腔镜免钉合经腹部分腹膜外网片植入术(transabdominal partial extraperitoneal,TAPE)与腹腔镜经腹腹膜前修补术(transabdominal preperitoneal,TAPP)的并发症及临床疗效。方法:回顾分析2007年7月至2010年6月为38例患者行免钉合TAPE(TAPE组)及为65例患者行TAPP(TAPP组)的临床资料,对比两组手术时间、住院时间、住院费用、疼痛视觉模拟评分(visual analogue scales,VAS)及3年复发率。结果:两组患者手术时间差异有统计学意义(P<0.05);住院时间、住院费用、术后1周VAS评分差异无统计学意义(P>0.05);术后半年TAPE组及TAPP组VAS评分分别为(0.37±0.13)分及(1.62±0.44)分,差异有统计学意义(P<0.01);3年复发率分别为2.63%、3.08%,差异无统计学意义(P>0.05)。结论:免钉合TAPE及TAPP治疗腹股沟疝均是安全、有效的,免钉合TAPE在缩短手术时间及减少慢性疼痛方面具有一定优势。     

腹腔镜腹股沟疝修补术的初期应用体会

目的:探讨初期开展腹腔镜腹股沟疝修补术的注意事项,术中、术后常见并发症及其处理措施。方法:回顾分析2012年10月至2013年5月为21例患者行腹腔镜腹股沟疝修补术的临床资料,其中19例行全腹膜外疝修补术(totally extraperitoneal,TEP),2例行经腹腹膜前疝修补术(transabdominal preperitoneal,TAPP)。结果:1例TEP患者中转行TAPP。手术时间TEP平均(92±41.38)min,TAPP平均(122±26.38)min,术中腹壁下血管损伤1例,腹膜撕裂5例,均无血清肿、内脏损伤、尿潴留及输精管损伤,未见切口及深部创面感染,术后未使用止痛剂。患者均于术后第1天恢复正常饮食并下床活动。患者术后第1、3、6个月获得电话随访,无腹股沟区慢性疼痛及复发。结论:熟悉、掌握腹腔镜下腹膜前间隙及其重要结构、选择合适的手术方式是避免腹腔镜腹股沟疝修补术中、术后并发症发生的关键。     

Proceed? Mesh for Laparoscopic Ventral Hernia Repair

Background and Objectives:

Laparoscopic technique to repair ventral hernia offers advantages over conventional open surgery such as shorter recovery time, decreased pain, and lower recurrence rates. There are a myriad of meshes available for laparoscopic repair of ventral hernias. This study evaluated the outcomes of laparoscopic repair of ventral hernias with Proceed mesh (Ethicon, Somerville, NJ, USA) in a single academic institution.

Methods:

An institutional review board–approved retrospective review was performed for 100 consecutive patients with ventral hernia who underwent a laparoscopic approach at our institution from August 2006 to February 2009. All patients were operated on by a single surgeon using a standard technique with transabdominal suture fixation and tacks.

Results:

The study included 100 consecutive patients (57 female and 43 male patients). The mean age was 55 years (range, 16–78 years), and the mean body mass index was 33.3 kg/m² (range, 19.6–68.9 kg/m²). Of the repairs, 27% were performed for a recurrent hernia. The mean and median size of the defect were 128 cm² and 119.5 cm² (range, 4–500 cm²), respectively. To ensure appropriate mesh overlap, the mean size of mesh was 253 cm² (range, 36–700 cm²). There were 4 conversions. The mean operative time was 117 minutes (range, 35–286 minutes). The mean length of stay was 1.9 days. There were no major abdominal complications. With a mean follow-up period of 50 months (range, 38–68 months), we have not recorded any recurrences. No mesh-related complications have been documented.

Conclusions:

The laparoscopic approach to ventral hernia repairs using Proceed mesh is associated with a low conversion rate and no major complications. At 50 months of follow-up, the recurrence rate is 0%. There were no mesh-related complications.     

腹部切口疝的诱因分析与治疗进展

腹部切口疝是腹部手术常见的并发症之一,腹部切口疝形成的两大直接原因是腹部手术切口愈合不良和腹内压升高,所以引起切口愈合不良和腹内压升高的因素都是切口疝的诱因.目前手术治疗是腹部切口疝唯一的根治方法,主要包括开放性手术和腹腔镜手术两种.本文对近年来腹部切口疝诱因、治疗方面的研究进行综述,并对其治疗前景进行展望.     

不同手术方式治疗腹壁造口旁疝24例

目的 探讨造口旁疝的病因、修补方法及临床疗效.方法 回顾性分析2006年7月至2010年7月安徽医科大学第二附属医院收治的腹壁造口旁疝64例,手术治疗24例,比较三种手术方式的术后复发率及并发症情况.结果 行Onlay修补术5例,复发1例,复发率20%.行Sublay修补术12例,复发2例,复发率16.66%;出现皮下积液、切口感染3例.行IPOM修补术7例,复发1例,复发率14.28%;出现肠粘连肠梗阻症状1例,出现肠漏1例.三组手术方式相比,IPOM及Sublay修补术造口复发率稍低,但无统计学意义（χ2=0.462,P=1.000）.预防性使用补片病例无一例发生造口旁疝,造口旁疝发生率低于常规手术组（χ2=1.533,P=0.539）.结论 造口旁疝发病率较高,修补术后复发率高,并发症多,至今仍无统一的修补标准.预防性放置补片可有效的降低造口旁疝发生率.     

Desarda法修补腹股沟疝与人工合成补片疝修补术的疗效比较

目的 探讨Desarda法修补腹股沟疝与人工合成补片疝修补术方法的临床效果.方法 回顾性分析2010年1月至2013年1月广州军区武汉总医院对150例腹股沟疝患者,随机分为Desarda法疝修补术组（A组）、传统平片无张力疝修补术组（B组）、完全腹膜外疝修补术组（TEP）（C组）的临床资料进行分析比较.结果 A组的手术时间显著短于B、C二组（t=13.0、9.8,P=0.000、0.015）.A组术后患者的下床活动恢复时间、住院时间低于B组（t=12.2、9.6,P=0.020、0.000）,而与C组比较差异无统计学意义（t=0.45、0.39,P=0.815、0.496）.A组术后并发症发生率低于B、C二组（χ2=4.150、1.298,P=0.035、0.026）.随访1～3年,三组患者均无复发.术后3 d检测患者的白细胞数、C-反应蛋白（C-RP）和白细胞介素-8（IL-8）,三间比较差异均有统计学意义（F= 23.015、22.512、9.505,P均=0.000）.结论 Desarda法疝修补的疗效明显优于传统平片无张力疝修补术及TEP术,同时能够有效减少医用材料费用,是更符合人性化的治疗方法,临床效果好.