A case-control study of risk factors for intussusception among infants in eastern France after the introduction of the rotavirus vaccine

ObjectiveThe objective of the present study was to investigate the risk factors for intussusception (IS) among infants, including vaccination against rotavirus.MethodsCase-control study with systematic inclusion of all infants aged <1 year with suspected IS admitted to emergency departments in the eastern region of France between 1 April 2008 and 31 March 2012. All cases classed level 1 according to the Brighton classification were matched to 4 hospital controls. Two exposure windows were examined; exposure to the first dose of rotavirus vaccine in the 7 and in the 14 days prior to the occurrence of IS.ResultsA total of 115 cases were matched with 457 controls. The average vaccination coverage rate over the 4 years of study was 8.6%. Rotavirus vaccine was not found to be significantly associated with the occurrence of IS in the 7 days (odds ratio (OR) not calculated; p = 0.99) and in the 14 days after administration of one dose vaccine (OR 1.33, 95% confidence interval (CI) 0.14–12.82). Infant formula alone or combined with breastfeeding was associated with an excess risk of IS (OR 2.74, 95% CI 1.10–6.79). A history of gastroenteritis within 2 weeks prior to hospitalisation was also associated with an increased risk (OR 2.24, 95% CI 1.07–4.67).ConclusionOur study indicates that infant formula alone or combined with breastfeeding is a risk factor for IS. A small, non-significant increase in the risk of IS was observed after rotavirus vaccination, although the low vaccine coverage rate likely precluded detection of a significant increase in risk.     

Perceived Value of a Pharmacy Resident Teaching Certificate Program

Objective

To determine the value of completing a pharmacy resident teaching certificate program on graduates'' current positions of employment.

Design

Annually from 2003 to 2007, program graduates of the Indiana Pharmacy Teaching Certificate (IPTeC) program were invited to take a 13-question Web-based survey 1 year after completing the program.

Assessment

Fifty-three of the 62 graduates (85%) surveyed responded. Almost half of the respondents strongly agreed or agreed that having completed the IPTeC program helped them obtain their current position. More than 90% of respondents agreed or strongly agreed that the seminar participation and teaching experience from the IPTeC program helped them in their current position. About 80% of respondents would recommend the program to others.

Conclusion

Completing a pharmacy resident teaching certificate program helped some graduates obtain and excel in their current position.     

医疗器械三级质量控制管理体系在临床疑似不良事件管理中的应用研究

目的:构建医疗器械三级质量控制管理体系,探讨其在临床疑似不良事件管理中的应用效果.方法:选取医院临床在用的1830台(套)医疗器械,按照管理模式将其分为对照组[896台(套)]和观察组[934台(套)],对照组采用常规管理,观察组采用三级质量控制管理,根据风险分析要素和评估值,将其分为高风险、中风险和低风险3类,制定一...     

Risk for prostate cancer by occupation and industry: A 24-state death certificate study

Current knowledge of the etiology of prostate cancer is limited. Numerous studies have suggested that certain occupations and industries may be associated with the occurrence of prostate cancer. Information on occupation and industry on death certificates from 24 states gathered from 1984 to 1993 was used in case control study on prostate cancer. A total of 60,878 men with prostate cancer as underlying cause of death was selected and matched with controls who died of all other causes except cancer. Similar to the findings of our parallel large case control study of prostate cancer, we observed excess risks in some white-collar occupations, such as administrators, managers, teachers, engineers, and sales occupations. However, some blue-collar occupations, such as power plant operators and stationary engineers, brickmasons, machinery maintenance workers, airplane pilots, longshoreman, railroad industry workers, and other occupations with potential exposure to PAH also showed risk of excess prostate cancer. Risk was significantly decreased for blue-collar occupations, including farm workers, commercial fishermen, mechanics and repairers, structural metal workers, mining, printing, winding, dry cleaning, textile machine operators, cooks, bakers, and bartenders. Although we observed excess risks of prostate cancer among some low socioeconomic status (SES) occupations, the overall results suggest that the effects of higher SES cannot be ruled out in associations between occupational factors and the risk of prostate cancer. Am. J. Ind. Med. 34:413–420, 1998. © 1998 Wiley-Liss, Inc.     

数字证书在医院信息系统中的应用

目前电子病历的法律地位还未得到认可,数字化医院制度和法制建设滞后阻碍了医院信息化建设前进的步伐.但随着《中华人民共和国电子签名法》的发布,一系列相关法规的出台,为医疗文书电子化运作,尤其是数字证书的应用创造了良好的法律环境和条件.根据《电子签名法》的相关规定,采用法规上认可的第三方数字认证方式,结合数字证书在上海市长宁区中心医院的实际应用情况,对实施过程和实施中遇到的问题及体会进行了讨论.