浅谈网闸在医院中的应用

本文从目前医疗行业中的网络现状出发,系统介绍了网闸的发展历程、概念和工作原理.并结合网闸在我院的应用实践,提出了保障医院内部网络可靠、安全、高效运行的策略,实现与外网的数据交换.     

Reactive oxygen species initiate a metabolic collapse in hippocampal slices: potential trigger of cortical spreading depression

Excessive accumulation of reactive oxygen species (ROS) underlies oxidative damage. We find that in hippocampal slices, decreased activity of glucose-based antioxidant system induces a massive, abrupt, and detrimental change in cellular functions. We call this phenomenon metabolic collapse (MC). This collapse manifested in long-lasting silencing of synaptic transmission, abnormal oxidation of NAD(P)H and FADH₂ associated with immense oxygen consumption, and massive neuronal depolarization. MC occurred without any preceding deficiency in neuronal energy supply or disturbances of ionic homeostasis and spread throughout the hippocampus. It was associated with a preceding accumulation of ROS and was largely prevented by application of an efficient antioxidant Tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl). The consequences of MC resemble cortical spreading depression (CSD), a wave of neuronal depolarization that occurs in migraine, brain trauma, and stroke, the cellular initiation mechanisms of which are poorly understood. We suggest that ROS accumulation might also be the primary trigger of CSD. Indeed, we found that Tempol strongly reduced occurrence of CSD in vivo, suggesting that ROS accumulation may be a key mechanism of CSD initiation.     

海岛县区1451例乙肝网络直报监测分析

目的：探索乙型肝炎（乙肝）监测数据的网络直报情况,为制定预防控制措施提供科学依据。方法：采用描述性流行病学研究方法分析。结果：2004-2008年乙肝累计报告发病1451例,年均报告发病率为73.35/10万,占甲乙类传染病发病构成逐年递增,订正后年均报告发病率为76.23/10万。病例报告分类以慢性乙肝为主,占76.97%。报告发病以15-54岁的中青年为主,15岁以下儿童一直处于低水平,55岁以上人群有逐年递增趋势;发病率男性高于女性;较集中在工人、家务及待业、农民、干部职员等人群。结论：定海区的乙肝年度丢失病例数约为2%-3%,乙肝分类报告越来越规范,建议乙肝疫情评价指标可用现患率或病例报告率代替发病率。另外,加强慢性乙肝病人的管理以及进一步做好工人、农民和老年人等重点人群的疫苗接种工作,对于乙肝在公共卫生防治方面具有重要意义。     

高职高专《中医诊断学》多媒体网络课件的研究与实践

介绍高职高专院校《中医诊断学》多媒体网络课件研制方面的体会,包括教学内容体系、媒体与界面的设计以及网络课件的特色等,并对课件的具体应用效果进行了调查。     

2006-2008年上海市普陀区传染病网络直报工作评价

目的评价上海市普陀区传染病网络直报工作质量,进一步提高网络直报质量,完善疫情报告系统。方法从国家疾病监测信息系统导出疫情数据并进行评价。结果对2006-2008年网络直报信息质量进行综合分析,报告及审核及时率逐年提高,2008年报告及时率达100%,审核及时率达99.84%,审核时间逐年缩短;报告准确性连续3年无明显改变,主要是性别和诊断日期的填写存在不一致;14岁以下卡片家长姓名填写率低。结论近年来普陀区传染病信息报告管理工作取得较大进展,但报告规范性等方面仍存在不足,需要进一步改进。     

上海世博园区环卫车船监控系统信息化研究

介绍了一种在上海世博园区实施的新型环卫车船监控系统,该系统采用新型的车(船)载终端并基于无线测控网技术构建而成。分析了系统的监控对象和需要达到的目标,以及监控系统设计;总结了与传统环卫车(船)载GPS系统相比较其特点。     

浅析数字化影像在放射治疗质量保证中的应用

通过各种KV级、MV级实时数字化影像和三维重建影像在放疗质量保证中的应用，为放疗射野中心及治疗范围的验证，摆位精度校正和放疗设备和物理特性检查方面提供了有效的手段．使得放射治疗的质量和精度都得到很大提高。     

浙江省开化县网络直报前后乙类传染病报告情况比较

目的　比较开化县实行网络直报前后乙类传染病报告情况的差异。方法　用2001-2003年开化县乙类传染病数据作为网络直报前数据，与2004-2006年网络直报后乙类传染病数据进行比较。结果　网络直报后，各级医疗机构乙类传染病平均填卡时间由4.47 d增加到7.20 d、平均报告时间由13.54 d减少到3.92 d；各级医疗机构报告传染病构成比变化均有统计学意义；肠道、呼吸道、自然疫源及虫媒传染病构成比变化有统计学意义。结论　网络直报提高了疫情报告的及时性、报告发病数。     

Anti-idiotypic antibodies to anti-acetylcholinereceptor antibody: Characterization by ELISA and immunoprecipitation assays

The idiotype network is important both as a means of autoregulation of immune mechanisms and a potential tool for manipulation of abnormal responses. In the autoimmune disease myasthenia gravis the acetylcholine receptor (AChR) is the target of an aberrant immune response. In this study we compare 2 widely used methods of antibody determination--immunoprecipitation radioimmunoassay (IPRA) and enzyme-linked immunoassay (ELISA)--for their ability to detect both anti-AChR antibodies (polyclonal and monoclonal) and anti-idiotypic antibodies raised against polyclonal anti-AChR antibodies. Although the IPRA is considerably more sensitive for the detection of monoclonal anti-AChR antibodies, the 2 methods produce similar results in the detection of anti-idiotypic antibodies to the anti-AChR immune response. The 2 techniques also demonstrated specificity of the reagents for idiotypes associated with the anti-AChR response and absence of effect on an idiotype associated with the control antigen, ovalbumin. The results demonstrate that the idiotypic repertoire of the polyclonal anti-AChR response in C57B1/6 mice is sufficiently restricted that antigen-specific blocking anti-idiotypic antibodies can be raised in rabbits by immunization with anti-AChR antibodies.     

危重症护理技术协作网络的构建

为了提高医院的危重症患者的护理质量和抢救成功率及生命质量。采用前瞻性的实践方法构建了护理技术协作网络。通过组织危重症患者的护理技术培训、查房与会诊和扩大危重症护理技术协作网范围、将量化手段引入管理，还应用重症病人评估积分网络管理病人，应用危重症护理技术训练测评系统管理护理人员，提高了护理人员的素质，使人力资源得到合理配置，促进了医疗质量和两个效益的明显提高。由此不难看出，危重症护理技术协作网络有应用推广价值。