全文获取类型
收费全文 | 4601篇 |
免费 | 288篇 |
国内免费 | 30篇 |
专业分类
耳鼻咽喉 | 89篇 |
儿科学 | 173篇 |
妇产科学 | 78篇 |
基础医学 | 388篇 |
口腔科学 | 122篇 |
临床医学 | 661篇 |
内科学 | 760篇 |
皮肤病学 | 66篇 |
神经病学 | 561篇 |
特种医学 | 57篇 |
外科学 | 382篇 |
综合类 | 389篇 |
现状与发展 | 1篇 |
预防医学 | 723篇 |
眼科学 | 71篇 |
药学 | 226篇 |
3篇 | |
中国医学 | 93篇 |
肿瘤学 | 76篇 |
出版年
2024年 | 7篇 |
2023年 | 126篇 |
2022年 | 186篇 |
2021年 | 257篇 |
2020年 | 213篇 |
2019年 | 245篇 |
2018年 | 278篇 |
2017年 | 177篇 |
2016年 | 184篇 |
2015年 | 121篇 |
2014年 | 359篇 |
2013年 | 352篇 |
2012年 | 264篇 |
2011年 | 314篇 |
2010年 | 235篇 |
2009年 | 247篇 |
2008年 | 280篇 |
2007年 | 220篇 |
2006年 | 168篇 |
2005年 | 115篇 |
2004年 | 98篇 |
2003年 | 89篇 |
2002年 | 57篇 |
2001年 | 50篇 |
2000年 | 49篇 |
1999年 | 46篇 |
1998年 | 38篇 |
1997年 | 22篇 |
1996年 | 22篇 |
1995年 | 12篇 |
1994年 | 7篇 |
1993年 | 5篇 |
1992年 | 8篇 |
1991年 | 10篇 |
1990年 | 5篇 |
1989年 | 12篇 |
1988年 | 9篇 |
1987年 | 4篇 |
1986年 | 5篇 |
1985年 | 5篇 |
1984年 | 1篇 |
1983年 | 2篇 |
1982年 | 5篇 |
1981年 | 2篇 |
1980年 | 2篇 |
1979年 | 1篇 |
1978年 | 1篇 |
1973年 | 1篇 |
1972年 | 2篇 |
1970年 | 1篇 |
排序方式: 共有4919条查询结果,搜索用时 234 毫秒
101.
102.
103.
《Journal of the American College of Cardiology》2020,75(19):2446-2458
BackgroundGreater early left ventricular mass index (LVMi) regression is associated with fewer hospitalizations 1 year after transcatheter aortic valve replacement (TAVR). The association between LVMi regression and longer-term post-TAVR outcomes is unclear.ObjectivesThe purpose of this study was to determine the association between LVMi regression at 1-year post-TAVR and clinical outcomes between 1 and 5 years.MethodsAmong intermediate- and high-risk patients who received TAVR in the PARTNER (Placement of Aortic Transcatheter Valves) I, II, and S3 trials or registries and were alive at 1 year, we included patients with baseline moderate or severe left ventricular hypertrophy (LVH) and paired measurements of LVMi at baseline and 1 year. The associations between LVMi regression (percent change between baseline and 1 year) and death or rehospitalization from 1 to 5 years were examined.ResultsAmong 1,434 patients, LVMi was 146 g/m2 (interquartile range [IQR]: 133 to 168 g/m2) at baseline and decreased 14.5% (IQR: 4.2% to 26.1%) to 126 g/m2 (IQR: 106 to 148 g/m2) at 1 year. After adjustment, greater LVMi regression at 1 year was associated with lower all-cause death (adjusted hazard ratio [aHR]: 0.95 per 10% decrease in LVMi; 95% confidence interval [CI]: 0.91 to 0.98; p = 0.004; aHR of the quartile with greatest vs. least LVMi regression: 0.61; 95% CI: 0.43 to 0.86; p = 0.005). Severe LVH at 1 year was observed in 39%, which was independently associated with increased all-cause death (aHR of severe LVH vs. no LVH: 1.71; 95% CI: 1.20 to 2.44; p = 0.003). Similar associations were found for rates of cardiovascular mortality and rehospitalization.ConclusionsAmong patients with moderate or severe LVH treated with TAVR who are alive at 1 year, greater LVMi regression at 1 year is associated with lower death and hospitalization rates to 5 years. These findings may have implications for the timing of valve replacement and the role of adjunctive medical therapy after TAVR. 相似文献
104.
105.
106.
Lenka HODACOVA Zdenka SUSTOVA Eva CERMAKOVA Martin KAPITAN Jindra SMEJKALOVA 《Industrial health》2015,53(1):48-55
The purpose of the study was to describe the occurrence of the most common
complaints related to MSDs in Czech dentists and to assess the risk factors affecting
them. A questionnaire survey of 581 Czech dentists (the response rate 72.6%) was conducted
in 2011. The questionnaire ascertained general information about the respondents, their
work habits and environment along with the occurrence of musculoskeletal disorders. The
respondents filled out the questionnaires during the educational events organized by the
Czech Dental Chamber. At least mild difficulties associated with the motoric system were
reported by 96.9% of the respondents, with 66.3% of respondents reporting moderate or
major difficulties. Back and neck pain followed by shoulder pain and headache were the
most common complaints in our sample. According to our data: age, gender, length of
practice, a history of serious MSDs, the occurrence of MSDs in blood relatives, the
perception of work as psychologically demanding, and especially a perceived moderate/bad
general health were significantly associated with the four most common musculoskeletal
complaints. Some of the factors were found as protective. This study suggests that MSDs
represent a significant burden for Czech dentists and further research is needed to
elucidate this issue. 相似文献
107.
108.
目的:通过对患儿家长抗生素知识的调查,了解他们对抗生素知识的掌握情况。方法随机选取2011年8~10月在北京三家医院就诊的1500名患儿家长,进行有关抗生素知识的问卷调查,回收有效回卷1416份。结果被调查者中46.00%知道细菌感染时要用抗生素,34.20%认为病毒感染要用抗生素。儿童普通伤风感冒(鼻塞、流涕及打喷嚏)时,认为需要使用抗生素的人占16.83%,一般咽炎或扁桃体炎(非化脓性)时该比例为36.92%,气管炎时为51.13%,肺炎时为68.90%。男性家长与女性家长答题的正确率分别为41.27%、42.55%,两者相比无明显差异(Χ2=40.059,P=0.021)。三级医院与二级医院患儿家长的答题正确率分别为43.44%、40.52%。两者相比差异有显著性(Χ2=82.969,P<0.01)。结论目前抗生素仍存在一定程度滥用情况,患儿家长对于抗生素应用指征认知不足,需进一步加强对于患儿家长抗生素知识的教育工作。 相似文献
109.
Lindsey M. Philpot Priya Ramar Muhamad Y. Elrashidi Tiffany A. Sinclair Jon O. Ebbert 《Mayo Clinic proceedings. Mayo Clinic》2018,93(10):1431-1439
Objective
To evaluate the impact of opioid controlled substance agreements (CSAs) enrollment on health care utilization.Patients and Methods
We retrospectively evaluated health care utilization changes among 772 patients receiving long-term opioid therapy for chronic noncancer pain enrolled in a CSA between July 1, 2015, and December 31, 2015. We ascertained patient characteristics and utilization 12 months before and after CSA enrollment. Decreased utilization was defined as a decrease of 1 or more hospitalizations or emergency department visits and 3 or more outpatient primary and specialty care visits. Multivariate modeling assessed demographic characteristics associated with utilization changes.Results
The 772 patients enrolled in an opioid CSA during the study period had a mean ± SD age of 63.5±14.9 years and were predominantly female, white, and married. The CSA enrollment was associated with decreased outpatient primary care visits (odds ratio [OR], 0.16; 95% CI, 0.14-0.19) and increased diagnostic radiology services (OR, 1.22; 95% CI, 1.02-1.47). After CSA enrollment, patients with greater comorbidity (Charlson Comorbidity Index score >3) were more likely to have reduced hospitalizations (adjusted OR, 2.8; 95% CI, 1.3-6.0; P=.008), reduced outpatient primary care visits (adjusted OR, 2.0; 95% CI, 1.2-3.2; P=.005), and reduced specialty care visits (adjusted OR, 2.0; 95% CI, 1.2-3.3; P=.006).Conclusion
For patients receiving long-term opioid therapy for chronic noncancer pain, CSA enrollment is associated with reductions in primary care visits and increased radiologic service utilization. Patients with greater comorbidity were more likely to have reductions in hospitalizations, outpatient primary care visits, and outpatient specialty clinic visits after CSA enrollment. The observational nature of the study does not allow the conclusion that CSA implementation is the primary reason for these observed changes. 相似文献110.
Molly E. Marino Emily C. Dore Pengsheng Ni Colleen M. Ryan Jeffrey C. Schneider Amy Acton Alan M. Jette Lewis E. Kazis 《Archives of physical medicine and rehabilitation》2018,99(3):521-528