产力异常产妇62例临床护理

目的探讨产力异常产妇的临床护理。方法对62例产力异常产妇进行护理评估,并针对性采取护理措施。结果 62例产力异常产妇经过精心细致的治疗和护理,均成功分娩,无并发症发生。结论对产力异常产妇在围生期进行密切观测,并有针对性地采取护理干预措施,能够提高分娩成功率,保证产妇及胎儿安全度过分娩期。     

针对性护理模式对冠心病心绞痛患者心率血压及心理状态的影响分析

目的 探讨针对性护理模式在冠心病心绞痛患者临床治疗中的应用效果,结合患者的心率血压及心理状态变化情况进行评价。方法 选取解放军东部战区总医院心血管内科2019年2月至2020年2月期间收治的74例冠心病心绞痛患者作为研究对象,应用随机数字表法,分为观察组37例,进行针对性护理模式,对照组37例,进行常规护理,对比两组患者的护理效果。结果 与对照组相比,观察组患者在护理后的心率(HR)水平[(76.17±4.82)次/min vs.(80.62±3.94)次/min]、收缩压(SBP)水平[(134.42±10.25)mmHg vs.(143.57±11.94)mmHg]、舒张压(DBP)水平[(88.92±7.63)mmHg vs.(44.73±5.05)mmHg]、心绞痛发作频次[(0.52±0.13)次/周vs.(1.47±0.31)次/周]以及焦虑自评量表(SAS)评分[(38.14±4.37)分vs.(93.71±5.09)分]相对更低(P0.05),与对照比,观察组患者的护理满意度相对更高(P0.05)。结论 冠心病心绞痛患者的治疗恢复期间,针对性护理模式的应用,可以有效纠正患者的心率、血压异常,同时改善其心理状态,减少症状的发作,改善患者的预后。     

Coxsackievirus-induced acute neonatal central nervous system disease model

Coxsackievirus B (CVB) is a significant pathogen that causes pediatric central nervous system disease with acute syndromes commonly. The onset of its infection was abrupt, and after recovery there usually will be severe mental sequelae. The disease model for research was not established by the way of natural infection, although there are various investigations about the CVB-induced central nervous system (CNS) diseases. Thus, we have established an acute neonatal CNS disease mice model by CVB orally infecting. This model imitated the natural infection route and focuses the onset of CNS disease, inducing severe infection and lesion in the hippocampus and cortex regions, and the stability of the model was demonstrated. A pathology score system was developed for quantitative pathology analysis, which standardizes the CNS pathology analysis by statistics analysis. By this model, the track of CVB penetrating the blood brain barrier in vivo has been captured. One of the experimental strains CVB3/Macocy, as a new variant, was isolated, and its genomic RNA was cloned. According to its nucleotide sequence, we have characterized its genomic structure and defined its genotype. Based on the sequence, some mutations which do not change the CVB-induced CNS damage have been found. The model is an effective tool for studies on CVB-induced CNS diseases.     

Effect of Transmural Extent of the Simulated Infarction in a Left Ventricular Model on Displacement and Strain Distribution Estimated from Synthetic Ultrasonic Data

The identification of a sub-endocardial infarction is of major interest in cardiology. This study evaluates the sensitivity of selected measures to the thickness of such an infarction. Synthetic ultrasonic data (long-axis view) of left ventricular models with inclusions were generated using Field II and meshes obtained from finite-element simulations, which also provided the reference for the estimates obtained from ultrasonic data. The displacements, the first and second component of the principal strain (ε₁ and ε₂), and several measures derived from these quantities were estimated. All estimates, except for the poorly estimated ε₂, exhibited sensitivity to the presence and transmurality of the inclusion. The most sensitive was the gradient of the averaged transmural profiles of ε₁, and ε₁ averaged over the area corresponding to the transmural inclusion. The inflection point of the ε₁ profile shifted toward the outer wall with increasing thickness of the non-transmural inclusion.     

Third International Meeting on Progress in Radio-Oncology

Summary

Phthalocyanines are photosensitizers evaluated for use in photodynamic therapy of cancer. As such, the dependence of the bioresponse on the light fluence rate may be of clinical importance. The effect of the fluence rate of white light from 0·165 to 3·3 kJ m^?2 min^?1 was studied in Chinese hamster cells and human lymphocytes, using as endpoints colony-forming ability and inhibition of [³H]thymidine incorporation following mitogenic stimulation and dye-photoactivation, respectively. Using Chinese hamster cells exposed to photoexcited chloroaluminium phthalocyanine tetrasulphonate in PBS solution, cytotoxicity was diminished as the fluence rate was reduced. In human lymphocytes changing the fluence rate between 0·33 and 3·3 kJ m^?2 min^?1 affected the response in a way similar to that of Chinese hamster cells. Human lymphocytes, when exposed to incremental increasing light fluences, 4 h after a conditioning dose, were able to recover from phthalocyanine-induced photo-damage, as evidenced by the reappearance of a shoulder on the dose-effect curve. This recovery process during a protracted light exposure, could explain the reduced sensitivity to phthalocyanine photosensitization, compared to exposure at high fluence rates.     

中国地理资源期刊集群平台期刊特约专栏实施成效分析与启示

【目的】 依据中国地理资源期刊集群平台期刊特约专栏出版实践,分析实施成效,总结出版经验,为同行组织特约专栏提供借鉴。【方法】 采用中国知网的统计数据,分析中国地理资源期刊集群7种平台期刊在2016—2017年刊发的特约专栏的表现。【结果】 特约专栏整体上能够提高期刊影响力,推广学术传播,但不同类型的特约专栏的表现存在差别。【结论】 内容型专栏是提升期刊影响力的有效措施,双盲评审、相似主题的间隔时间及同一作者的出现频次是特约专栏成效的重要影响因素。特约专栏的组织需要与科技创新一致,落实“四个面向”的战略部署。