垂体后叶素在腹腔镜下卵巢囊肿剥除术中的应用研究

目的探讨经腹腔镜行卵巢囊肿剥除术中垂体后叶素的使用价值。方法回顾分析经腹腔镜卵巢囊肿剥除术120例的临床资料,随机分为观察组和对照组各60例。观察组巧克力囊肿20例、畸胎瘤20例、卵巢单纯性囊肿20例,均为单侧。对照组巧克力囊肿20例、畸胎瘤20例、卵巢单纯性囊肿20例,也均为单侧。观察组分别于卵巢囊肿剥除前在正常卵巢皮质与囊肿壁间注射垂体后叶素稀释液（浓度15%）,然后行囊肿剥除术,对照组直接剥除。比较两组手术时间、术中出血量、囊肿破裂率、术后卵巢功能。卵巢功能的判断采取术前及术后月经恢复情况及术后3、6、12个月测定的卵泡刺激素（FSH）水平。结果观察组手术时间、术中出血量、术中肿块破裂率、术后月经恢复天数明显少于对照组（P〈0.05）,术后住院天数两组差异无统计学意义（P〉0.05）;术前和术后的FSH水平在对照组存在显著差异（P〈0.05）,在观察组差异不大（P〉0.05）。结论使用垂体后叶素注射分离法在腹腔镜下卵巢囊肿剥除术中能达到易于分离、较好止血及减少卵巢功能伤害。     

腕关节镜辅助治疗腕骨内腱鞘囊肿

目的：探讨腕关节镜治疗腕骨内腱鞘囊肿的方法及疗效。方法2013年5月—2014年5月,应用腕关节镜治疗腕骨内腱鞘囊肿5例,其中月骨3例,舟骨1例,三角骨1例。主要症状为腕部不适、疼痛,伴握力下降和活动度降低。 X线平片及CT显示腕骨内圆形或类圆形骨密度减低区,边界清楚,有硬化缘。 MRI显示病灶内为液体。采用腕关节镜下病灶刮除＋自体松质骨或注射型人工骨移植术治疗,术后腕关节功能位固定3周。结果5例均获得随访,平均6.8个月。所有病例无复发,植骨愈合满意。患者腕关节疼痛及不适症状明显缓解,术后均恢复正常的生活工作。结论腕关节骨内腱鞘囊肿是慢性腕关节疼痛原因之一,腕关节镜技术在腕骨内腱鞘囊肿的治疗中,手术方法安全,并发症少,功能恢复快,手术效果满意。     

颌骨囊肿开窗减压术后受累牙牙髓活力变化的临床研究

目的研究探讨颌骨囊肿开窗减压术后受累牙牙髓活力的变化,为临床该类患牙的处理提供处理依据。方法选择2013年7月至2013年12月在我院就诊的颌骨囊肿患者100例,采用开窗减压术进行治疗,术后1个月、3个月定期随访,观察囊肿受累牙的牙髓活力状态的数值术前、术后的变化情况。结果 100例患者术后均愈合良好。共测量患牙130颗,正常牙130颗,术前电测牙髓无活力或活力显著降低者共96颗,占所有被累及患牙的73.8%。术后1³个月,部分牙髓活力降低的患牙其牙髓活力获得恢复,术后3个月随访时,共有12例患牙的牙髓活力恢复了正常。术后13个月,部分牙髓活力降低的患牙其牙髓活力获得恢复,术后3个月随访时,共有12例患牙的牙髓活力恢复了正常。术后1³个月,亦有部分牙髓活力降低的患牙其牙髓活力进一步减退,术后3个月随访时,共有4例患牙的牙髓丧失了活力。结论在进行颌骨囊肿开窗减压术前,对牙齿进行牙髓活力测试,可为牙齿的保留和处理提供参考。     

腹腔镜下卵巢囊肿剥除术不同止血方式对残留卵巢功能的影响研究

目的探讨在腹腔镜下卵巢囊肿剥除术采用不同方式止血对残留卵巢功能的影响。方法对2012年1月-2013年8月该院收治的126例卵巢囊肿患者进行回顾性分析,按照治疗方法分为观察组和对照组各63例,对照组采用电凝止血,观察组采用镜下缝合法止血,比较2组血清雌二醇（E2）、促卵泡激素（FSH）、促黄体生成素（LH）、卵巢间质血流收缩期峰值（PSV）及卵巢窦卵泡数。结果 2组术后1个月E2水平、PSV及卵巢窦卵泡数明显低于术前,FSH水平明显高于术前,但是对照组降低或升高的程度明显高于观察组,差异有统计学意义（P〈0.05）,观察组术后6个月E2、FSH、LH水平、PSV及卵巢窦卵泡数与术前比较差异无统计学意义（P〉0.05）。结论采用镜下缝合法止血对腹腔镜下卵巢囊肿剥除术患者卵巢功能的影响明显小于电凝止血。     

Systematic review and meta-analysis of observational studies on BD-IPMNS progression to malignancy

BackgroundThe vast majority of presumed branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs) of the pancreas are referred to a surveillance program due to the relatively low risk of malignancy. We aim to evaluate all available data from observational studies focused on the risks of BD-IPMN progression and malignancy to provide vital insights into its management in clinical practice.MethodsA comprehensive search was conducted at PubMed, Cochrane, Web of Science and Embase for observational studies published before January 1st, 2020. The progression of BD-IPMN was defined as the development of worrisome features (WFs) or high-risk stigmata (HRS) during surveillance. Overall malignancy was defined as all malignancies, such as malignant IPMN, concomitant pancreatic ductal adenocarcinoma (PDAC) and other malignancies, including BD-IPMN with high-grade sec. Baltimore consensus 2015 or BD-IPMN with high-grade dysplasia (carcinoma in situ) sec. WHO 2010. A meta-analysis was performed to investigate the presence of a mural nodule as a possible predictor of malignancy.ResultsTwenty-four studies were included, with a total of 8941 patients with a presumed BD-IPMN. The progression rate was 20.2%, and 11.8% underwent surgery, 29.5% of whom showed malignancy at the final pathology. Of those, 78% had malignant IPMNs, and 22% had concomitant pancreatic cancer. Overall, 0.5% had distant metastasis. The meta-analysis showed that the risk of malignancy in the presence of a mural nodule >5 mm had a RR of 5.457 (95% CI 1.404–21.353), while a nonenhancing mural nodule or an enhancing mural nodule < 5 mm had a RR of 5.286 (95% CI 1.805–15.481) of harboring malignancy.ConclusionMost presumed BD-IPMNs entering surveillance do not become malignant. Of those submitted to surgery, concomitant PDAC adds to the overall risk of detecting malignancy.     

腹腔镜下巨大卵巢囊肿穿刺抽液的一种简便方法

目的 探讨腹腔镜下巨大卵巢囊肿穿刺抽液的简便方法.方法 2008年6月~2012年1月,68例单纯性巨大卵巢囊肿行腹腔镜下卵巢囊肿剥除术或切除术,囊肿直径10~20 cm,平均15 cm.术中使用穿刺套管（套管鞘cannula＋棱锥形套管针trocar）稍用力穿刺囊壁进入囊腔,退出trocar,然后插入吸管,抽吸囊内液体.结果 手术均在腹腔镜下完成,术中6例囊液外溢.手术时间30~55 min,平均40 min,术中出血30~100 ml,平均55 ml,术后病理回报均为良性肿瘤（57例浆液性囊腺瘤,11例黏液性囊腺瘤）,未发生并发症.结论 该方法应用于腹腔镜下巨大卵巢囊肿剥除术或切除术中,简单易行,安全有效,值得临床推广使用.     

单纯性肾囊肿的个体化治疗方案探讨

目的根据肾囊肿的部位个体化选择治疗方案,以提高单纯性肾囊肿的外科治疗效果。方法回顾性分析398例单纯性肾囊肿患者的临床资料,分析患者全身情况、囊肿位置及囊肿大小等特点与成功治疗肾囊肿的相关性。结果接受经皮穿刺引流并反复注射无水乙醇或联合生物蛋白胶的患者225例,接受经腹腔镜肾囊肿去顶减压术联合生物蛋白胶治疗的患者158例,接受输尿管镜下内切开引流术者15例。其中有效率99.5%,治愈率94.0%,无其他脏器损伤、感染性休克、化学性肾盂肾炎等严重并发症。结论单纯性肾囊肿患者应根据肾囊肿部位、个体化选择治疗方法。     

颅内肠源性囊肿四例报告并文献复习

通过对经手术和病理证实的4例肠源性囊肿患者临床资料的回顾,结合相关文献对其病因学、临床特点、诊断和治疗进行总结。颅内肠源性囊肿是一种良性病变,以中年女性多见,好发于中线部位,高发症状或体征多与占位效应相关,影像学检查无特征性改变,缺乏明确诊断标准,难以与其他颅内囊性病变相鉴别,术前诊断困难且误诊率高,明确诊断需依靠术中所见和病理检查。手术全切除是唯一治愈手段。     

Prevalence of odontogenic cysts and tumors associated with impacted third molars: A systematic review and meta-analysis

PurposeThis systematic review aimed to investigate the prevalence of odontogenic cysts and tumors associated with impacted third molars (ITM).MethodsOnly studies that performed histopathological diagnosis of lesions were eligible for inclusion. Five main electronic and three grey literature databases were searched. Risk of bias (RoB) of included articles was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Studies Reporting Prevalence Data.ResultsFrom 1,300 studies identified, 16 met the inclusion criteria. Seven studies were classified as high, seven as moderate, and two as low RoB. The prevalence of odontogenic cysts and tumors associated with ITM was 5.3% (95%CI: 3.1%–8.1%) of ITM. Odontogenic cysts in particular were found in 4.4% (95%CI: 2.5–6.8%) of the extracted ITM, whilst odontogenic tumors in 0.5% (95%CI: 0.2–0.9%). The dentigerous cyst was mentioned in eleven studies with a pooled prevalence of 2.1% (95%CI: 1.4–3.1%). The odontogenic keratocyst was cited by nine studies and had a prevalence of 0.5% (95%CI: 0.2–0.7%). The radicular cyst was mentioned only in three articles and the pooled prevalence was 4.7% (95%CI: 0.0–19.4%)ConclusionOdontogenic cysts and tumors were found in 5.3% of ITM extracted. The most common lesions were the radicular cyst, dentigerous cyst, and odontogenic keratocyst.