“军卫一号”数据库“瘦身”方法设计

目的：实现“军卫一号”数据库“瘦身”,提高整个系统的运行速度。方法：离线式整理表空间,降低高水位线,或在线式重建表空间,缩减数据文件。结果：2种方法都可成功实现数据库的“瘦身”,且能使系统平稳运行。结论：2种方法都具有可行性,且可操作性强,可提高整个“军卫一号”系统的运行效率。     

Cutting Efficiency of Reciproc and WaveOne Reciprocating Instruments

Introduction

The aim of the present study was to evaluate the cutting efficiency of 2 new reciprocating instruments, Reciproc and WaveOne.

Methods

Twenty-four new Reciproc R25 and 24 new WaveOne Primary files were activated by using a torque-controlled motor (Silver Reciproc) and divided into 4 groups (n = 12): group 1, Reciproc activated by Reciproc ALL program; group 2, Reciproc activated by WaveOne ALL program; group 3, WaveOne activated by Reciproc ALL program; and group 4, WaveOne activated by WaveOne ALL program. The device used for the cutting test consisted of a main frame to which a mobile plastic support for the handpiece is connected and a stainless steel block containing a Plexiglas block (inPlexiglass, Rome, Italy) against which the cutting efficiency of the instruments was tested. The length of the block cut in 1 minute was measured in a computerized program with a precision of 0.1 mm. Means and standard deviations of each group were calculated, and data were statistically analyzed with 1-way analysis of variance and Bonferroni test (P < .05).

Results

Reciproc R25 displayed greater cutting efficiency than WaveOne Primary for both the movements used (P < .05); in particular, Reciproc instruments used with their proper reciprocating motion presented a statistically significant higher cutting efficiency than WaveOne instruments used with their proper reciprocating motion (P < .05). There was no statistically significant difference between the 2 movements for both instruments (P > .05).

Conclusions

Reciproc instruments demonstrated statistically higher cutting efficiency than WaveOne instruments.     

Test–retest reliability of health state valuation techniques: the time trade off and person trade off

Economic analysis is increasingly being employed in formal resource allocation decision‐making processes in health care. As a consequence, the methods employed by economic analysts are increasingly subject to close scrutiny. One such area of methodology concerns the instruments used to elicit preferences for various health states for use in the construction of quality‐adjusted life years. There are a number of techniques which may be used to elicit preferences and different techniques produce different results. The objective of this study was to explore the test–retest reliability of two techniques: Time Trade Off (TTO) and Person Trade Off (PTO) valuations were collected by a general population postal survey. A total of 798 respondents returned questionnaires. The intra class correlation coefficients ranged from 0.40 to 0.88 for TTO and, ?0.17 to 0.82 for PTO, with the majority of coefficients being >0.50. The reliability coefficients varied between techniques and health states, with the TTO technique tending to produce higher coefficients. While the reliability results for TTO were generally positive, the reliability results for PTO are less clear. Copyright © 2010 John Wiley & Sons, Ltd.     

Masthead,Volume 65, Issue 1

At sufficiently high Larmor frequencies, traveling electromagnetic waves along a magnet bore can be used for remote magnetic resonance excitation and detection, effectively using the bore as a waveguide. So far, this approach has relied only on the lowest waveguide modes and thus has not supported multiple‐channel operation for radiofrequency shimming and parallel imaging. In this work, this limitation is addressed by establishing a larger number of propagating modes and tapping their spatial field diversity with multiple waveguide ports. The number of available modes is increased by loading with dielectric inserts; the ports are implemented by stub and loop couplers at the end of a waveguide extension. The resulting traveling‐wave array, operated at 298 MHz in a 7T whole‐body magnet, is shown to enable radiofrequency shimming as well as parallel imaging with commonly used acceleration factors. The last part of the study concerns the amount of dielectric loading that is required. For the given Larmor frequency and bore dimensions, it is found that rather few water‐filled inserts, occupying ～5% of the bore cross‐section, are sufficient for effective parallel imaging. Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc.     

湖南娄底地区汉族人群内皮素基因rs5370G/T多态性研究

目的了解湖南省娄底地区汉族人群原发性高血压相关的内皮素(ET-1)基因的rs5370G/T单核苷酸多态性(single nucleotide polymorphism,SNP)分布,并与Genbank多种族人群进行比较。方法收集湖南娄底地区84名无血缘关系的汉族人群的静脉血,其中健康个体57名,高血压患者27名,提取DNA,应用PCR/SNP敏感性分子开关对ET-1基因rs5370G/T多态性进行分析,并与Genbank中的多种族人群的分布进行比较分析。结果湖南娄底地区汉族人群中ET-1基因rs5370G/T的G、T的频率分别为51.2%和48.8%,且不同性别间高血压人群与正常人群间均未见显著差异,在高血压人群与正常人群中G的频率分别为0.537,0.518(χ2=0.056,P>0.05)。然而在Genbank中,ET-1基因rs5370G/T的G、T基因频率分别为80.4%和19.6%,与湖南娄底地区人群比较有显著性差异(χ2=22.132,P<0.001)。结论湖南娄底地区汉族人群中ET-1基因rs5370G/T多态性与高血压无相关性,与Genbank中的多种族人群比较分布有明显的差异,这种差异可能是导致高血压在不同种族间的表现有所不同的遗传因素之一。     

非脱垂子宫阴式子宫全切的创新应用

目的:寻求并发症少、手术操作安全的非脱垂子宫阴式子宫切除术式。方法:对非脱垂子宫阴式子宫切除术进行创新,术前1天阴道准备,即10%的氯化钾、2%的双氧水加碘伏冲洗阴道2次,番泻叶30g代茶饮。手术当天清洁灌肠,术前30min给予5%葡萄糖注射液50ml加头孢噻肟钠2.0g静脉推注。3%的垂体后叶素盐水60ml注入阴道穹隆黏膜下,电刀沿穹隆部环形切开阴道黏膜,打开前后穹隆,进入腹腔,窄S拉钩分别自前后穹隆部伸入腹腔拉开,暴露术野。术中根据子宫大小采取对半、去核、碎解的单一或联合应用。结果:该术式并发症少、手术操作安全、手术时间短、创伤小、出血少,明显优于传统术式。结论:创新术式并发症少、手术操作安全增加了非脱垂子宫阴式子宫切除术的安全性及易行性并扩大了适应证。     

Identifying cut-off scores with neural networks for interpretation of the incontinence impact questionnaire

We propose to determine cut-off scores for the Incontinence Impact Questionnaire (IIQ) based on the neural network (NN) approach. These cut-off scores should discriminate between patients having poor, moderate, or good quality of life (QoL) secondary to their incontinence problems. Data from two prospectively completed QoL questionnaires, the IIQ (n = 237) and the MOS 36-Item Short-Form Health Survey (SF-36) (n = 237), were analyzed using NN and conventional statistical tools. Kohonen networks identified three distinct clusters of IIQ scores. The three clusters represent the full spectrum of possible scores on the IIQ. We interpreted these clusters as reflecting good, moderate, and poor QoL. We estimated that a score of less than 50 on the IIQ would be representative of good QoL, between 50 and 70 would be moderate QoL, and greater than 70 would be indicative of poor QoL. Validation with the SF-36 data confirmed these categories. The present study demonstrated that the NN approach is opening new areas in the interpretation and clinical usefulness of QoL questionnaires. NN allowed the identification of three levels of QoL and should be useful in clinical decision making.