关节松动术与超短波治疗颞下颌关节紊乱症

颞下颌关节紊乱症是口腔科常见病和多发病,在口腔颌面疾病中其发病率约占第四位,在人群中发病率为28%~88%[1]。临床表现为颞下颌关节区周围肌肉疼痛,下颌关节运动异常,关节运动时伴有杂音和弹响。本文采用关节松动术结合超短波治疗颞下颌关节紊乱症49例,现报告如下:1资料与方法     

毛冬青注射液细胞毒性及类过敏反应的评价

目的:研究毛冬青注射液的安全性,为临床合理用药提供参考.方法;通过L-929细胞毒性实验和RBL-2H3细胞脱颗粒实验,考察毛冬青注射液的临床毒性大小以及是否存在类过敏的不良反应.结果:毛冬青注射液在高浓度时(333 μl·ml-1)抑制细胞增殖,低浓度时(111 μl· ml-1)促进细胞增殖,并有浓度依赖性,同时会引起部分RBL-2H3细胞脱颗粒.结论:细胞毒性实验可用于评价药物的毒性大小;细胞脱颗粒实验可用于评价药物的类过敏反应.     

低氧预适应血管内皮细胞增加神经细胞低氧耐受

目的:研究经低氧预适应处理的血管内皮细胞分泌的物质对神经细胞低氧耐受的影响.方法:分别将人微血管内皮细胞(HMEC-1)经过低氧预适应(HPC)处理及正常培养,分离其培养基并通过滤膜过滤.人神经母细胞瘤细胞系(SH-SY5Y)细胞分为低氧预适应组(HPC组)、培养基对照组(Medium-C组)和空白对照组(SY5Y-C组),三组细胞分别加入经HPC的HMEC-1细胞的培养基、正常培养HMEC-1细胞的培养基和正常培养SH-SY5Y细胞的培养基.随后三个组细胞均给予低氧处理.使用MTS法检测神经细胞活力,Western Blot检测caspase-3蛋白表达水平.结果:SY5Y-C组、Medium-C组和HPC组的细胞活力分别是(0.9967±0.0033)、(1.0751±0.0447)和(1.4737±0.0325),HPC组细胞活力显著增加(P<0.05);三个组caspase-3蛋白表达的相对丰度分别是(0.9950±0.0050)、(0.9893±0.0787)、(0.8180±0.0361),HPC组细胞的caspase-3蛋白表达显著受到抑制(P<0.05).结论:内皮细胞在经过低氧预适应处理后分泌的物质可以增加神经细胞的低氧耐受.     

杨广源教授辨治咳嗽变异性哮喘经验

咳嗽变异性哮喘是一种特殊的哮喘,主要临床表现为阵发性、刺激性干咳,夜间尤甚。现代中医多将其归于"风咳"范畴[1]。杨广源教授认为本病的病因病机、症候表现均与"风"有关,故提出"风淫喘息,治病求本",以"疏风宣肺,缓急解痉"为主要治法,自拟复方过敏煎,宣散并用,直切病机。以此为基础方,随症加减,灵活应用,临床疗效显著。     

针刺联合胎盘间充质干细胞治疗脑性瘫痪大鼠模型

BACKGROUND:Both of acupuncture and mesenchymal stem cell transplantation have therapeutic effects on cerebral palsy. OBJECTIVE:To explore the therapentic effect of acupuncture combined with placenta derived mesenchymal stem cells on rat cerebral palsy. METHODS:Thirty-five Wistar rats were equivalently randomized into five groups, including control group, model group, acupuncture group, transplantation group and combination group. Rat models of cerebral palsy were prepared in all groups except the control group. At 7 days after modeling, in the transplantation group, 10 μL placenta derived mesenchymal stem cells were transplanted into the right cerebral cortex and striatum of rats; rats in theacupuncture group were given acupuncture at Shuigou (DU26), Dazhui (DU14), Baihui (DU20), Guanyuan (RN4) and Qihai (RN6) points; rats in the combination group given acupuncture and transplantation treatment as described above; the model and control groups received no treatment. Then, after 7-day intervention, the body mass, neurological function and pathological changes of rat brain tissues were measured and observed, respectively.  . RESULTS AND CONCLUSION:The order of the growth rate of body mass was as follows: control group > combination group > acupuncture and transplantation groups > model group, and all groups had significant differences except the two groups of acupuncture and transplantation (P < 0.05); findings from holding tract, foot error and water finding in maze tests showed the neurological function was best in the control group, followed by the combination group, as well as acupuncture and transplantation groups, and the worst in the model group. All groups had significant differences except acupuncture and transplantation groups (P < 0.05). Besides, in the model group, cells in the brain and hippocampus decreased, arranging disorderly with fuzzy structure, and inflammatory cells appeared; pathological changes in the other groups were in between control group and model group, Additionally, brain tissues in the combination group exlibited better pathological changes than those in the acupuncture and transplantation groups, which were similar with the normal brain tissues. To conclude, acupuncture, placenta derived mesenchymal stem cells transplantation, or their combination can improve neurological function in rats with cerebral palsy, especially the combination treatment.     

探测器位姿对三维CT重建图像质量的影响分析

分析了探测器位姿误差对三维CT重建图像质量的影响,计算机模拟和MTF曲线对比结果表明:探测器沿x、y、z方向的位移不会对重建质量产生影响,只影响断层的位置.而其绕x、y、z三坐标轴的摆动会对重建图像质量造成影响,偏摆角控制在±0.2°以内、俯仰角控制在±1.0°以内、扭转角控制在±0.4°以内即可满足重建图像的质量要求...     

宫腹腔镜诊治46,XY真两性畸形2例分析

<正>1病例简介病例1,患者,13岁,社会性别女,因"发现外阴异常13年"于2010年10月5日入院。患者为第1胎足月顺产,其母否认孕期服用甾体激素类药物史,出生时阴蒂肥大,定期复查,阴蒂无明显增大,无月经来潮及周期性腹痛;生长发育及智力无异常。其祖父母为表兄妹结婚,家族中无类似患者。查体:身高145cm,指距145cm,体重32kg,颈部喉结未见明显突出;未见腋毛、阴毛,双侧乳房己发育,外阴呈女性发育,阴     

刍议剖宫产分娩医疗费用

目的 分析单病种剖宫产的医疗费用,为医疗费用体制的改革提供参考依据.方法 利用本院2005～2008年单病种住院医疗费用的统计报表,分析住院患者的医疗费用增长情况.结论 4年间剖宫产医疗费用呈上升趋势,药品费用增长是最主要原因.     

强脉冲光在面部痤疮治疗中的应用

目的：观察强脉冲光（IPL）对面部痤疮治疗效果。方法：采用皇后光子嫩肤仪对面部痤疮患者进行治疗,设定波长为560nm～585nm的宽谱线光源,能量密度为20j／cm～40j／cm,每位患者3次～6次不等,治疗间隔为21d。结果：65例患者痊愈,患者十分满意。43例患者症状明显改善,现仍在疗程中,无1例不良反应,有效率为100％。结论：IPL对痤疮治疗是一种40新性、无创伤性、有效的美容技术,对痤疮治疗有显著的疗效,是痤疮治疗的新途径。