眼内芨芨草异物误诊一例

患者丁×× ,男 ,8岁 ,住院号 5 3 2 12。 2 0 0 1年 3月 12日玩耍时被他人用芨芨草戳伤右眼 ,当时疼痛、流泪、不能睁眼 ,在当地医院诊断为右眼角膜穿孔伤并行清创缝合手术 ,术后抗炎、止血、对症处理 ,眼痛、流泪症状好转 ,但视力仍差。转省级某医院诊断为右眼外伤性白内障 ,做视觉电生理检查 :右眼视网膜视神经功能减退 ,给予抗生素眼液滴眼治疗。 5月 10日被发现右眼内有灰白色物 ,并逐渐扩大 ,患儿右眼出现剧烈疼痛、畏光、流泪。 1周后入我院治疗。全身检查未见异常。眼部检查 :右眼视力无光感 ,左眼 0 3 ,矫正视力 + 6 0 0ＤＳ　 + …     

良性巨大卵巢囊肿微创手术探讨附2例报告

现代外科手术治疗，要求安全、准确、有效地去除病变，并尽量减少破坏正常组织以及尽可能保持其功能，这就是以最小的创伤获得最大的治疗效果。我院近2年，对2例巨大卵巢囊肿进行术前充分评估，采用耻上小切口配合腹腔镜探查下进行微创手术治疗，效果满意，现报告如下。     

CALCIUM ANTAGONISTS IN PREVENTION OF HYPERTENSION AND STROKE IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS

To investigate the effect of Calcium antagonists (Ca-An) with different tissue specificity in the devel- opment of hypertension and stroke in salt-loading SHRSP, three experiments were conducted. In exper- iment I (1), 50 8-week-old male SHRSP were divided into three groups and given nifedipine (NF, 32mg / kg /day), menidipine (MN 32mg / kg / day)and placebo (control group)respectively. In the controJ group 83.3%(15 / 18)died of stroke and 17 showded renal vascular sclerosis. Their average lifespan was 84 days. NF and MN significantly re- duced systolic blood pressure (SBP), and no stroke of renal vascular sclerosis developed.ln experiment I(2), 54 7-week-old male SHRSP were divided into three groups (18 in each group). They were treated with nimodipine (NM)20mg / kg / day, 2mg / kg / day and placebo respectively. NM (20mg / kg / day) markedly lowered SBP and postponed the onset of stroke. Only 11% died in 17 weeks. NM (2mg / kg / day did not lower SBP but postpond the onset of stroke. In exper- iment 11 (1), 29 10-week-old female SHRSP were di- vided into three groups: Group A was given NF 32mg / kg / day, group B was parathyoidectomized (PTX) and group C served as control. PTX group did not lower SBP but could postpone the onset of stroke. In experiment Ⅱ (2), 33 male SHRSP were divided into three groups and ticated as desctibed above :in experiment Ⅱ (I)(ll in each group). Seven weeks after the experiment, the brain blood flow of NF group was significantly greater (67.5%)than that of the control and PTX groups. In experiment II, 27 7-week-old male SHRSP were divided into three groups as described above in experiment I(2). Two weeks after the treatment, significant difference was found in norepinephrine (NE)contents of the anterior hypothalamic region (AHR)between NM (20mg / kg / day)group and control group (2 870 vs 2 304 pg / mg tissue). Our results show that Ca-An (nimodipine)can re- verse the NE depletion by high salt in SHRSP, thus lower SBP and prevent stroke.     

甘露醇治疗脑卒中致肾损害36例分析

1　临床资料1 1　一般资料　 3 6例中男 2 0例 ,女 1 6例 ,年龄 40～87岁 ,平均年龄 63 8岁 ,>60岁 2 3例 (63 % )。全部病例均经头部ＣＴ证实 ,其中脑出血 1 5例、蛛网膜下腔出血 6例、脑梗死 1 4例、混合性脑卒中 1例。有高血压病病史 2 6例 ,糖尿病病史 6例 ,冠心病病史 8例 ,风心病病史 2例 ,全部病例均无肾脏病史。治疗前观察 2 4ｈ尿量均 >1 5 0 0ｍｌ和实验室尿液分析 ,血肌酐(Ｃｒ)、尿素氮(ＢＵＮ)均在正常范围。1 2　甘露醇治疗与肾脏损害及结果　 3 6例除用2 0 %甘露醇外 ,未用其他对肾脏有损害的药物。甘露醇用法 :2 5 0ｍｌ…     

糖尿病血瘀证患者HbA_(1c)和FA水平的研究

目的 :探讨糖尿病血瘀证同血糖和非酶糖化之间的关系。方法 :对 4 0例合并血瘀证与 35例无血瘀证的 2型糖尿病患者的血糖、果糖胺和HbA1c等指标进行检测和比较 ,并以 2 5例查体健康者作为对照。结果 :同健康对照组相比 ,糖尿病血瘀证和非血瘀证患者空腹血糖、餐后 2h血糖、果糖胺、糖基化血红蛋白水平均明显增高 (P<0 .0 1) ;同非血瘀证组相比 ,HbA1c水平明显增高 (P <0 .0 5 )。结论 :长期高血糖和蛋白非酶糖化是糖尿病血瘀证的重要危险因素 ,HbA1c可作为糖尿病血瘀证的重要标志物之一。     

激光闭合术治疗下肢静脉曲张患者的护理

下肢静脉曲张是血管外科最常见的疾病。传统大隐静脉曲张高位结扎及剥脱术治疗，由于手术创伤大、术后瘢痕明显、康复时间长等原因，患者往往难以接受。自2006年10月以来，我科对18例患者采用激光闭合术治疗下肢静脉曲张，取得了满意的疗效．现报道如下。[第一段]     

Differentiation of human epidermal stem cells into fibroblasts induced by TGF-β1 in vitro

Objective To investigate the correlation between human epidermal stem cell (hESCs) and hypertrophic scar or keloid. Methods Improved collagen Ⅳ-coated adhesion methods was used to isolate and culture the epidermal stem cells after neutral protease selectively digested the dermo-epidermal junctions. After the cells were cultured and expanded in vitro, and passage 3 hESCs were induced by different concentrations of TGF-β1 (0.1, 5.0, and 10.0 ng/ml). Morphological fea-tures and identification of these cells were meseasured by HE, Masson, immunohistochemical staining on the days 3 and 7, respectively. Results After induced by TGF-β1 for 3 and 7 days, the morpholo-gy of the epidermal stem cell (hESCs) was changed into fusiform shape, similar to fibroblasts. 70 % ofthe cell which was induced by TGF-β1 were blue stained in the cytoplasm by Masson stain, which is the distinctive method for collagen, suggesting collagen appeared or increased in the cells. The collagen concentrations in supernatants of hESCs were 0.4150±0.0014, 0.3380±0. 0020, and 0.3870±0.0020, much higher than that in control group (0.0780±0.0025) and normal skin fibro-blast group (0.15004±0.0051) (P<0.05). Immunohistochemical staining revealed that positive rates of these cells for anti-vimentin staining were more than (95.00±1.20)% in experiments and (5.70±0.20)% in control group. Conclusion The differentiantion of hESCs induced by TGF-β1 into fibro-blasts indicates that hESCs may play a role in the pathogenesis of hypetrophic scar and keloid.     

玉溪市首次发现艾滋病并弓形虫脑病1例

病例患者，男性，41岁，已婚，农民，因“间断发热、消瘦2月，伴发应迟钝、尿失禁3d”入院。患者既往有性乱史，4年前患过带状疱疹。患者家中饲养有狗。患者近2个月来无明显诱因出现间断发热，以午后发热为主，体温波动在37℃～38.0℃之间，无咳嗽、盗汗、腹痛、腹泻，近2个月体重无诱因下降10kg，无手抖、脾气暴躁，多次到我院门诊就诊，拟诊“上呼吸道感染”予抗生素治疗后，仍时有低热，近3d他人发现其反应迟钝，少言懒语，小便失禁，精神、饮食差，以“发热待查：①结核？②沙门氏菌感染？③AIDS？”收住院。     

二巯基丁二酸胶囊现场诊治铅中毒37例分析

我们应用二琉基丁二酸胶囊(DMSA)对37例铅中毒患者进行治疗．疗效较好，现报告如下。