胆汁中蛋白成分对胆固醇结石形成的影响

胆囊胆固醇结石的形成常与胆汁成分改变有关，但其确切机制及其始动因素尚未完全明了，该文就近年胆汁中蛋白质成分改变对胆石形成的影响及其可能机制方面研究成果作一综述。     

高血压性脑出血的显微手术治疗体会

本组统计我科2003-09～2003-12应用显微神经外科技术治疗高血压性脑出血32例，疗效满意，现报告如下。     

肾功能损伤分级系统在成人心脏术后的应用

Objective The aim of this study was to evaluate of adilty of two acute renal failure-specific scoring systenms (the classification by Bellome et al and the AKIN criteria) for predicting hospital mortality after cardiac surgery in adult patients. Methods Between October 1 st 2006 to Decemjber 31 st 2006, 509 adult patients who ungerwent coronary artery bypass grafting (CABG) and/ or valve operation were enrolled in this study. The medical data collection included gender, age, types of operation, perioperative he- modynamic parameters, urine output, biochemical parameters and outcome. Renal function was assessed daily according to the classi- ficatinn by Bellomo and the AKIN criteria, respectively. As references, Acure Physiology and Chronic Health Evaluation(APACHE) Ⅱ and Sepsis-related Organ Failure Assessment (SOFA) score were also calculated. Resuits Three hundred and forty-one patients were male (67.0%), and 168 were female (33.0%), mean age was (56.2±12.0) years old. Tnree hundred and nine patieats un- derwent CABG, 182 underwent valve operation and 18 underwent CABG plus valve operation, Mean duration of ventilation support was (20.4±17.7) houra, and the ICU stay was (1.4±1.0) days. Postoperative hospital stay was (13.8±9.1) days. According to the classification by Bellomo., the highest in-hospital mortality was 52.9% in ARFS group. Mahiplicatinn of in-hospital morality rate was abserved (X2 for trend, P<0.01) in 0.4% (non-ARF), 1.2% (stage 1), 12.0% (stal～ 2) and 32.4% (stage 3) of pa- tients based on the AKIN criteria. By applying the area under the receiver operating characteristic ourve, the classification by Bellomo and the AKIN criteria had good discriminative power. Furthering, multivariate logistic regression analysis verified that the Odds Ratio of the AKIN criteria was 5.478 (P =0.028, 95% Confidence Interval 1.027- 24.856), after adjusting for gender and age. Con- clusion Analytical data confinned good discriminative power of both the AKIN criteria and the classification by Bellomo for predicting hospital mortality of adult postoperative patient with ARF.     

高血压脑出血的超早期微创治疗

目的：探讨高血压脑出血的手术方式、手术时机对该疾病疗效产生的影响；方法：对23例高血压脑出血病人采取超早期小骨窗开颅显微镜下清除血肿，观察疗效；结果：远期ADL1～3级73．9％，死亡率8．7%；结论：小骨窗开颅显微镜下清除高血压脑出血创伤小、某些相对手术禁忌病人可以耐受手术，超早期手术是提高治愈率、降低致残率和死亡率的关键措施。     

听觉诱发电位指数及其两种计算模式

听觉诱发电位指数在麻醉／镇静深度监测中的作用越来越受到重视。本文就其两种计算模式即MTA model与ARX model的有关原理及临床应用作一综述。     

准分子激光角膜切削术治疗近视的并发症

为分析准分子激光角膜切削术（ＰＲＫ）治疗近视的并发症，对１３９例（２５７眼）ＰＲＫ术后随访半年至一年。结果表明：术后一年，低中度和高度组各有１眼最佳矫正视力丢失二行，分别占２．５％和３．３％；低中度和高度组的角膜上皮下１级混浊分别为１０．８１％和１５．１６％，２级混浊分别为２．７３％和０％；激素性高眼压，在发生率最高的３个月时，可分别达２４．３７％和２５．３２％，但这种反应性的眼压升高只是暂时的，容易控制；过矫和散光增加的发生率均较低，主要与术者的经验有关。随着术者经验的提高、手术设计的完善及术后用药的研究，这些并发症会降到最低水平。ＰＲＫ是安全、有效的。     

Orem自理模式在结肠造口恢复期中的应用

直肠癌发生的部位距肛门7cm以下占80％左右，低位直肠癌行腹部会阴联合切除术，同时做永久性的腹壁结肠造口。以往我们注重手术的成功率和生存率，而忽略了结肠造口的治疗及护理，影响了患的生存质量。我科对64例结肠造口患实行Orem自理模式护理，提高了患的生存质量，取得了良好的社会效益和经济效益。     

提高抗恶性疟独特型单抗克隆出现频率的方法学探讨

用Protein A-Sepharose亲和层析法提纯McAb-IgG,皮下多点和腹腔免疫雄性Wistar大鼠,间隔两周共3次,融合前3天采用腹腔、尾静脉和脾内注射等三种加强免疫方法,以间接ELISA法和抗体竞争ELISA法筛选Anti-Id阳性克隆。结果显示:融合前大鼠血清抗小鼠IgG或抗免疫原McAb-IgG滴度,静脉组和脾内组比腹腔组高一个滴度;Anti-Id阳性克隆出现频率,腹腔组为0.9％和0.3％,静脉组为11.0％和13.3％,脾内组为16.4％和12.9％,静脉组和脾内组明显高于腹腔组(P<0.01);上述三种加强免疫方法对抗小鼠IgG阳性克隆出现频率无明显影响(P>0.05);与腹腔加强免疫组相比,静脉和脾内加强免疫组也可提高细胞融合效果(P<0.01).本实验结果提示,腹腔和皮下多点多次长程基础免疫结合静脉或脾内加强免疫是制备Anti-Id McAb比较好的免疫方案。     

覆膜支架治疗椎动脉巨大外伤性假性动脉瘤一例

患者　女 ,3 8岁 ,因左颈乳突后部波动性包块 1个月而入院。患者 1个月前被锐器刺伤左颈部 ,当地医院给予分层缝合加压包扎治疗。 10余天前患者自觉左颈部肿胀疼痛 ,出现包块 ,且逐渐增大 ,到我院就诊。入院查体 :左颈乳突后部可见直径约 4 0 0ｍｍ搏动性包块 ,穿刺可见鲜红色血液。血管造影 :左椎动脉直径 3 9ｍｍ ,血流通畅。在颈 1 2(Ｃ1 2 )椎间隙后外侧可见一直径约 0 5ｍｍ破裂口 ,向后外侧软组织间形成动脉瘤。动脉瘤直径约 3 5 0ｍｍ ,血流随心脏搏动如吹气球样喷入动脉瘤 ,并行成涡流。右椎动脉造影显示该侧动脉纤细、迂曲 ,直…     

中晚期直肠癌的高热综合治疗临床研究

于1987年4月开展了对中晚期直肠癌的高热综合治疗临床研究，治疗结果显示，高热综合治疗能提高中晚期直肠癌的切除率，提高机体免疫反应，近期疗效明显，为直肠癌的综合治疗增加了一种可行的治疗方法。