后房型人工晶体植入术瞳孔管理的实践与体会

随着人工晶体材料、制怍工艺的发展及手术技术、器械的不断改进,近年来国内外已普遍推行白内障囊外摘除人工晶体植入术,特别是后房型人工晶体植入术,目前已认为是一种术后效果好、并发症少、安全可靠并符合眼的生理功能的手术。我们自1989年开展后房型人工晶体植入术,感觉到在开展此项手术时,术前、术中、术后的瞳孔管理非常重要,特别是术中、术后的瞳孔管     

低血糖昏迷误诊六例报告

低血糖昏迷因其无特异性 ,容易误诊而延误治疗。我们于 1999年 1月～ 2 0 0 2年 6月共收治低血糖昏迷患者 2 2例 ,其中误诊 6例 ,报告如下。临床资料本组 6例。男 4例 ,女 2例。年龄 4 7～ 65岁。首诊时诊断为脑血管意外 5例 ,心源性晕厥 1例。 6例入院前均有2型糖尿病史。发病     

CEA及LDH测定对良恶性胸水的鉴别诊断

ＣＥＡ及ＬＤＨ测定对良恶性胸水的鉴别诊断云春梅，杜钧，张汉丰，程丽桂（内蒙古自治区医院）１９９０～１９９１年我院收治的胸腔积液，对经临床、病理证实的４８例良性和１２例癌性胸水测定ＣＥＡ，对其中３４例结核性与１０例癌性胸水测定ＬＤＨ，结果分析如下。１对...     

中国汉族群体D4S111位点的遗传多态性研究

目的：研究中国汉族群体中α艾杜糖苷酶基因Ｄ４Ｓ１１１位点的遗传多态性。方法：采用扩增片段长度多态性（ＡｍｐＦＬＰ）分析技术，检测了广州地区汉族无血缘关系健康个体９７名。结果：Ｄ４Ｓ１１１位点，在９７名无关个体中发现５个等位基因和９种基因型，等位基因片段长度为８３０～５１０ｂｐ，基因频率为０００５２～０３６０８，ＰＩＣ为０５９６６，杂合性为０７８。结论：中国汉族群体中Ｄ４Ｓ１１１位点具有高度多态性，并与其它种族间存在差异性。     

腹腔镜下胆囊和卵巢良性囊肿联合切除8例分析

目的探讨电视腹腔镜下联合切除胆囊及卵巢囊肿的可行性及优势。方法回顾分析了8例患者的手术过程及治疗结果。结果8例患者均一次完成胆囊及卵巢囊肿切除术,无一例中转开腹。手术时间平均为105min,胆囊切除术平均为45min,卵巢囊肿切除平均为60min。住院日平均为6d。结论腹腔镜下联合切除胆囊、卵巢囊肿不增加手术的危险性及并发症,同时完成两种手术减少了患者的痛苦和手术费用。医患双方均满意。     

ACTIVIT OF HUMAN PLACENTAL GAMMA GLOBULININ BLOCKING IMMUNE FUNCTIONS IN VITRO AND IN ABROGATING THE XENOGENEIC, LOCAL GRAFT-VERSUS-HOST-REEACTEON

In order to understand the mechanism of immunosuppression caused by infusion of placental gamma globulin (PGG) in patients with renal allografts, rheumatoid arthritis, and graft – versus –host disease (GCHD) following bone marrow transplantation (BMT) ,we have examined the effect of PGG in vitro and in a model of the xenogeneic , local graft –ver- sus – host reaction (LGVHR) .PGG inhibited lymphocyte proliferation in mixed lymphocyte cultures (MLC) (P<0.005) and depressed interleukin -2 (IL-2) levels in such cultures at 72 hours (P<0.01) . In contrast phytohemagglutinin (PHA) –and pokeweed mitogen (PWM) –induced T and B lymphocyte blastogenesis was not affected by such PGG treatment .PGG treatment .PGG neither decreased the [3H] TdR pulse incorporation in unstimulated lymphocytes nor affected cell viability .Cell cycle analysis by flow cytometry showed that PGG reduced the percentage of cells in S and G2, M phases during the MLC, but did not alter cell cycling during PWM-stimulated proliferation . An immunosuppressive effect of PGG on the LGCHR was tested in a model of intracutaneous transplantation of PGG –treat human lymphocytes into cyclophosphamide – immunosuppressed rats. Lymphoprep – separated human tonsillar lymphocytes were incubated with RPMI-1640 buffer containing：（1）PGG,4mg/ml,(2) human plasma albumin,4mg/ml,(3)mitomycin-C,25ug/ml, or (4) no additive. Cell of each preparation (3x107cells in 0.1ml) were injected intracutaneously into cyclophosphamide-treated male rats at separate abdominal locations. A fifth site received only the buffer solution. Five days after injection of cells ,each rat received [125 I]IUdR (10uCi) intraperitoneally and was killed after 5 hours. For each site of injection, the diameters of induration were measured and 125 I was counted . There was no difference between buffer – treated and a ibumin – treated groups either in the diameter of the area of induration (t=0.66;P>0.5)or in radioactive counts(t=0.22;P>0.05).In the PGG –treated group, the induration and radioactivity measurements were significantly less than in control groups (t=3.72 and P<0.1;t=2.62 and P<0.02,respectively ) Cytophilic antibodies in PGG were thought to inhibit an early phase of T cell activation, and not to be cytotoxicity .In the LGVHR, the immune response might be abrogated either by immuno- regulatory suppression of T cell function or by toxicity to the infused lymphoid cells. For some clinical purposes, immuno- modulating, human antibodies might be preferred to murine, monoclonal antibodies.     

老年人几种常见病的发生原因及护理

随着年龄的增长，人的身体也在不断变化，一到了老年，人的身体在各方面的正常功能都开始退化，而一些对身体有危害的因素开始不断上升并恶化，为能让老年人顺利度过幸福晚年，及时正确地解除不利因素，现将几种常见病的发生原因及护理介绍如下。     

MRI阴性而PET阳性的颞叶癫痫:一组可应用手术治疗的症候群

多数非颞叶损害性癫痫(NLTLE)患者可通过高分辨率MRI发现其海马硬化(HS)。但是,也有少数NLTLE患者在电生理与临床上均表现为一侧颞叶癫痫,而MRI却无HS的证据。许多具有类似情况的患者经过18F-FDG-PET检查可发现相应的低代谢病灶,其病理生理机制尚不清楚。本研究旨在明确MRI未显示HS的NLTLE患者与那些MRI显示HS的NLTLE患者相比时是否表现出不同的临床病理学症候群。对30例伴有单侧EEG改变但MRI未显示HS的NLTLE患者(HS-veTLE)与30例年龄、性别匹配的伴有单侧EEG改变及MRI显示HS的NLTLE患者(HS+veTLE),在临…     

培养环境的温度变化与人MⅡ期卵母细胞纺锤体形态学变化的关系

目的:观察环境温度的改变对MⅡ期人卵纺锤体结构的影响.方法:40例非男性因素的不孕妇女,将常规体外授精后未受精的MⅡ期卵子置于室温(23～25℃)直至纺锤体消失.于纺锤体消失后,将卵子分成3个实验组:1组纺锤体消失后立即复温(n=8);2组纺锤体消失后室温下静置5 min再复温(n=6);3组纺锤体消失后室温下静置10 min再复温(n=6).卵子复温后5 min,10 min,2 h分别观察纺锤体的复现情况.结果:20个未受精的MⅡ期卵子置于室温下5 min内纺锤体均消失.1组中的8个卵子,2组中的6个卵子复温后再次观测到了MⅡ期纺锤体.3组中的6个卵子只有3个卵子再次出现了MⅡ期纺锤体.对照组的18个卵子放置于37℃恒温板上观察30 min,纺锤体均未见消失.结论:MⅡ期卵子纺锤体对环境温度的改变非常敏感.温度降低将导致纺锤体消失,随着时间的延长,纺锤体复现几率明显减少.     

早期和代偿期肝硬化的临床与病理学研究

我国属乙肝病毒感染发病率较高的国家，HBsAg携带者约1．2亿，每年新感染者在150万例以上，约10％-20％发展为肝硬化，约5％发展成肝癌，对人民健康及社会、家庭危害很大。客观存在迫使我们尽量在防治方面做些探讨，因而于20世纪80年代起再次在50年代病毒性肝炎重复肝活检发现肝炎和肝纤维化、肝硬化基础上，进一步研究肝硬化的病因、治疗和预防