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药品生产企业如何选择物料供应商 总被引:1,自引:0,他引:1
本文从药品生产的GMP管理角度 ,阐述了物料管理在药品生产企业生产活动中的重要意义 ,并提出了选择物料供应商的方法和一些切实可行的对物料供应商进行评审的程序。 相似文献
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目的以客观、量化的评价结果为医院考查药品供应商每个阶段的实际绩效并对其实施奖惩提供直接依据,不断促进其提升供应绩效水平。方法建立了一种对药品供应商进行阶段性连续评价的线性加权综合评价模型,详细阐述了其评价方法,并给出了该模型在药品供应商评价过程中的具体应用实例。结果线性加权综合法克服了以往医院在评价药品供应商的决策中存在的盲目性和人为性。结论线性加权综合法可作为医院评价药品供应商的一种实用有效的方法。 相似文献
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《Pharmaceutical development and technology》2013,18(1):39-51
In the past two decades, three categories of newer disintegrants have come into widespread use. These substances are a synthetic polymer (crospovidone), chemically modified starch (sodium starch glycolate) and cellulose (croscarmellose sodium). Multiple suppliers are now available for each category. Current NF monographs do not provide tests which reflect on their functionality and one cannot assume reliable performance of disintegrants from different sources meeting NF standards. The objective of this study was to identify differences in physical properties thought to be related to functionality among crospovidones from multiple sources. Physical properties examined included particle size and distribution, surface area, porosity and surface morphology. Disintegration and dissolution were performed on a model tablet formulation using either an insoluble or a soluble filler. Substantial differences in particle size and distribution, surface area, porosity and surface morphology were observed which correlated with differences in disintegration time and dissolution rate of the model drug from an insoluble tablet core. None of the differences in physical properties resulted in any differences in the disintegration or dissolution of the model drug from a soluble tablet core. 相似文献
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IAN J. McBEATH 《Clinical & experimental optometry》1981,64(1):9-14
ABSTRACT This paper seeks to summarise the legal responsibilities of optometrists in their practice of optometry. It is written with regard to Victorian optometrists but some modification may be needed in other States. 相似文献
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《Pharmaceutical development and technology》2013,18(3):419-430
Current NF monographs do not provide tests that reflect on the functionality of Crospovidone NF from multiple sources. Physical characterization studies such as particle size and distribution, surface area, porosity, and surface morphology revealed major differences among the crospovidones from different sources (Shah, U.; Augsburger, L.L. J. Pharm. Dev. Technol. 2001, 6 (1), 39–51). Differences in disintegration and dissolution were also observed for a model drug in an insoluble filler system (see Shah and Augsburger, 2001). The objective of this study was to determine the relationship between physical differences observed and disintegrant functionality and to develop standard performance test. Tests performed included settling volume studies, measurement of initial rate as well as extent of liquid uptake of the loose disintegrant powder, and simultaneous measurement of the axial and radial disintegrating forces along with the rate and extent of liquid uptake of the pure disintegrant compacts. Significant differences among the crospovidones were observed for all tests performed. Settling volume, liquid uptake, and disintegration force are recommended as standard performance tests to determine differences among crospovidones from different sources. 相似文献
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目的:了解我国医疗健康信息产品选型现状,发现当前行业选型的难点和需求,为推动行业发展提供依据。方法:通过网络问卷调查方式,对全国672名医疗机构信息人员进行调查,对调查数据进行统计分析。结果:目前医疗机构对于信息产品供应商和在用系统的整体满意度一般;选型时主要考虑系统稳定、功能全面以及供应商对客户的重视程度;医疗机构对于医疗健康信息产品测评机构和第三方信息发布平台的态度比较积极;行业协会的测评更受到医疗机构信赖。结论:供需双方在医疗健康信息产品选型方面均有很大的提升空间,建立科学的选型管理模式、构建专业的市场引导机制对于医疗信息化行业的健康发展十分必要。 相似文献
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