Gluma脱敏剂治疗牙本质过敏的疗效观察

目的评价Gluma脱敏剂对牙本质过敏的治疗效果.方法将40例132个患牙随机分为两组,分别采用氟化钠甘油和Gluma脱敏剂治疗并进行疗效对比.结果Gluma脱敏剂疗效明显优于氟化钠甘油.结论Gluma脱敏剂对牙本质过敏有较好的治疗效果.     

不同脱敏剂对楔状缺损充填后微渗漏的影响

目的:比较不同脱敏剂对楔状缺损充填后的微渗漏的影响。方法:选取30颗前磨牙随机分成3组并制作楔状缺损洞型,分别用MEdental,Gluma脱敏剂对牙本质进行表面处理,流动树脂充填,对照组牙本质表面不做任何处理,经牙合力循环、热循环后,用2%亚甲基蓝染色,24h后将每个离体牙由颊舌向沿牙长轴连续切下3片。在体视显微镜下放大40倍观察充填体边缘染液微渗漏情况,然后在SEM下观察流动树脂与牙体组织之间的粘结情况。结果:3组间充填体微渗率差异均有统计学意义(P0.05),以MEdental材料的边缘微渗率最低(P0.01);扫描电镜下观察可见:Medental组树脂与牙体组织结合良好,Gluma组树脂与牙体组织结合处部分位置出现裂隙,对照组树脂与牙体组织结合处存在裂隙且较Gluma组明显。结论:MEdental脱敏剂和Gluma脱敏剂均能降低楔状缺损充填后的微渗率,MEdental脱敏剂影响较大,使用Gluma脱敏剂和MEdental脱敏剂可以获得较好的边缘封闭性。     

三种脱敏剂对全酸蚀粘结剂牙本质粘结强度和界面形态的影响

目的:研究、比较三种脱敏剂对全酸蚀粘结剂牙本质粘结强度及其粘结界面形态的影响。方法:选择12个无龋损离体人磨牙,磨除牙合面釉质,用600目碳化硅砂纸在流水下预备出有统一玷污层的牙本质粘结面后,随机分为4组,分别用去离子水(对照组)和3种脱敏剂(Hybrid Coat、Gluma、极固宁)进行脱敏处理后,应用Single Bond 2在面粘结4 mm树脂。然后将每个牙垂直于粘结面切割出12个1.0 mm×1.0 mm×4.0 mm的粘结试件,分别在SEM下观察其粘结界面微观形态并进行微拉伸强度(μTBS)测试。结果:HybridCoat组粘结强度最高((14.81±3.87)MPa,随后依次为去离子水组(13.39±4.67)MPa、Gluma组(12.76±2.96)MPa和极固宁组(10.48±4.32)MPa,各组间两两比较,极固宁组明显低于其他3组(P﹤0.05),其他3组间相比均无显著性差异(P﹥0.05);Hybrid Coat组形成的树脂突大部分>35μm,长而密集;Gluma组形成的树脂突长7～35μm;极固宁组形成的树脂突长20～35μm,较稀疏。结论:Hybrid Coat和Gluma对全酸蚀粘结剂牙本质粘结强度无明显影响,而极固宁则明显降低其粘结强度。     

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目的评价氟保护漆在治疗金属烤瓷全冠（PFM）修复中活髓基牙预备后牙本质过敏症的疗效。方法选择2009年5月至2010年11月来德阳市口腔医院口腔修复科就诊的拟行PFM修复的患者124例（活髓基牙226颗）。按就诊顺序随机分为两组：试验组（65例,基牙116颗）采用氟保护漆脱敏;对照组（59例,基牙110颗）采用Gluma脱敏剂脱敏。分别于戴用PFM后即刻及3个月检测牙本质敏感状况。结果戴用PFM后即刻,试验组有效率为84．48％,对照组有效率为80．91％,二者差异无统计学意义（P〉0．05）;3个月时,试验组有效率为93．97％,明显优于对照组（84．55％）（P〈0．05）。结论氟保护漆可有效缓解PFM修复中活髓基牙预备后的敏感症状,值得临床广泛应用。     

复合树脂联合脱敏剂对楔状缺损牙敏感性及修复疗效的影响

目的：评价复合树脂充填楔状缺损时,联合应用脱敏剂对术后敏感和远期临床疗效的影响。方法：将167例542颗因楔状缺损导致牙本质敏感的患者按简单随机化分组方法,分为三组：涂布iBond七代自酸蚀粘接剂后复合树脂充填（A组）、涂布自酸蚀粘接剂可乐丽菲露后复合树脂充填（B组）及涂布舒齿灵脱敏剂后涂布可乐丽粘接剂七代自酸蚀粘接剂后复合树脂充填（C组）,比较术后脱敏疗效,并于充填后6、12及24个月用改良USPHS系统评价其远期临床疗效。结果：楔状缺损修补术后,各组牙牙本质敏感症状均有明显的缓解（尸〈0．05）;无牙本质敏感症状的牙所占比例A、C组显著性高于B组（P〈0．05）;三组在6、12个月时充填体成功率无显著差异,但C组24个月修复体成功率显著性低于A,B组。结论：对因牙本质敏感求治的楔状缺损患者,推荐术前使用脱敏剂或使用含有脱敏成分的粘接剂;使用iBond粘接剂进行复合树脂充填,能显著减少牙敏感症状,并且具有良好的粘接性能。     

Assessment of Demineralization Inhibition Effects of Dentin Desensitizers Using Swept-Source Optical Coherence Tomography

The purpose of this study was to evaluate the mechanism of action and the inhibiting effects of two types of desensitizers against dentin demineralization using pre-demineralized hypersensitivity tooth model in vitro. In this study, we confirmed that a hypersensitivity tooth model from our preliminary experiment could be prepared by immersing dentin discs in an acetic acid-based solution with pH 5.0 for three days. Dentin discs with three days of demineralization were prepared and applied by one of the desensitizers containing calcium fluoro-alumino-silicate glass (Nanoseal, NS) or fluoro-zinc-silicate glass (Caredyne Shield, CS), followed by an additional three days of demineralization. Dentin discs for three days of demineralization (de3) and six days of demineralization (de6) without the desensitizers were also prepared. The dentin discs after the experimental protocol were scanned using swept-source optical coherence tomography (SS-OCT) to image the cross-sectional (2D) view of the samples and evaluate the SS-OCT signal. The signal intensity profiles of SS-OCT from the region of interest of 300, 500, and 700 µm in depth were obtained to calculate the integrated signal intensity and signal attenuation coefficient. The morphological differences and remaining chemical elements of the dentin discs were also analyzed using scanning electron microscopy and energy-dispersive X-ray spectroscopy. SS-OCT images of CS and NS groups showed no obvious differences between the groups. However, SS-OCT signal profiles for both the CS and NS groups showed smaller attenuation coefficients and larger integrated signal intensities than those of the de6 group. Reactional deposits of the desensitizers even after the additional three days of demineralization were observed on the dentin surface in NS group, whereas remnants containing Zn were detected within the dentinal tubules in CS group. Consequently, both CS and NS groups showed inhibition effects against the additional three days of demineralization in this study. Our findings demonstrate that SS-OCT signal analysis can be used to monitor the dentin demineralization and inhibition effects of desensitizers against dentin demineralization in vitro.     

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??Abstract??Objective To evaluate the the sealing effects and abrasive resistance of ClinproTM XT Varnish and Oravive through scanning electron microscope ??SEM??. Methods Totally 48 freshly extracted human premolars were selected?? prepared into dentin discs?? and randomly divided into 3 groups ??group A?? control group?? group B?? ClinproTM XT Varnish group??group C?? Oravive group??. ClinproTM XT Varnish and Oravive were applied respectively on the exposed dentin surfaces of the B and C group in accordance with operating manual. Eight teeth of the B and C group were respectively selected for toothbrush abrasion test. Then an observation was made on the surface and the section plane by scanning election microscope and quantitative analysis was made with Image-Pro Plus 6.0. Results Both of the two desensitizers could occlude the dentinal surface?? and dentinal tubule area and the relative area of the two groups had no significant difference ??P > 0.05??. The two desensitizers could penetrate into the dentinal tubules at a certain depth?? but the penetration depth in group B was larger than that in group C ??P < 0.05???? after the toothbrush abrasion test?? the sealing effect in group B was markedly superior to that in group C ??P < 0.05??. Conclusion ClinproTM XT Varnish performs better than Oravive in sealing effect and abrasion resistance.     

中药脱敏剂治疗牙本质过敏的临床疗效观察

目的:观察中药脱敏剂治疗牙本质过敏的临床疗效。方法:选取牙本质过敏患者126例,随机分为研究组64例(患牙172颗)、对照组62例(患牙158颗),分别使用中药脱敏剂和氟化钠甘油进行治疗。观察2组患者在治疗后即刻、3个月后、6个月后的疗效,并进行统计学分析。结果:2组疗效比较有显著性差异(P<0.01)。结论:中药脱敏剂可有效治疗牙本质过敏,且使用方便,疗效相对持久。     

Gluma脱敏剂治疗牙本质过敏症的疗效观察

目的观察Gluma脱敏剂治疗牙本质过敏症的疗效。方法87例106颗牙本质过敏症的牙齿随机分为两组，实验组用Gluma脱敏剂脱敏，对照组用氟化钠甘油脱敏，比较两组近期疗效。结果实验组近期疗效明显高于对照组。结论Gluma脱敏剂治疗牙齿过敏症有较好疗效，值得推广应用。