多刚体大惯量非线性系统试验与在环仿真

为研究多刚体多自由度质量矩系统的动态特性,建立了大惯量非线性硬件在环仿真系统的数学模型和实物样机,研究了变参数PID改进算法。该试验系统用于多自由度质量矩平衡系统的动态响应分析、控制算法研究和复杂系统的解耦控制。试验结果表明：在±10°的干扰下该系统能够保持动态平衡,具有仿真效果符合实际工况、算法可行和有效的特点。     

2—酮基—L—古龙酸流加发酵过程的在线控制

开发了用于生产２－酮基－Ｌ－古龙酸（２ＫＧＡ）流加发酵过程的在线控制系统。该系统可在线检测和控制发酵温度、ｐＨ、ＤＯ、罐压等环境参数，并可控制糖液、碱液等补料的流加。经７０ｍ３环隙气升式发酵罐内的试验表明，该控制系统工作可靠，抗干扰能力强，控制品质好，便于操作，能满足生产工艺要求。     

TL-Ⅰ型履带式管道机器人双型控制系统设计

本文介绍了TL-Ⅰ型管道机器人的机械结构和控制系统,机器人的控制系统设计为手动控制和自主运动控制两种方式,可相互切换。同时具体介绍了控制系统的硬件和软件实现。对控制系统核心的开发,是基于ARM＋／μC／OS-Ⅱ的嵌入式开发架构。实验结果表明该系统运动状态稳定,有很高的可靠性和实用价值。     

风洞稳M数大系统的智能控制

介绍了风洞稳M数大系统的智能控制及其实现.该系统是一个由3个关联子系统构成的复杂的、变参数、非线性计算机控制系统,它包括:具有预测功能的风洞发动机最佳控制子系统,基于神经网络的旁路活门自适应控制子系统和柔壁控制子系统.应用最佳控制原理和智能控制技术,实现多目标优化控制的设计目标.试验表明:该控制系统具有稳M数控制精度高、鲁棒性强、响应快速、节省燃油等优点.     

预测函数控制在确定性网络控制系统中的应用

针对网络控制系统具有不确定时滞的特性,通过在节点中设置缓冲区的方法将随机时滞转化为确定性时滞,从而将网络控制系统从随机系统转化为确定性时滞系统;针对这类时滞系统利用预测函数控制算法设计了控制器,以实现基于模型匹配和多步预测的思想来改善控制性能。通过仿真和基于DCS的模拟系统实验,结果均表明了该方法的正确性和有效性。     

嵌入式系统设计的一种协同仿真方法

提出了一种基于C 平台的嵌入式系统设计的协同仿真方法。嵌入式系统的软件成分由C 实现，硬件成分由Verilog刻划。该方法的基本思路是将Verilog模块转化为C 程序，然后将软件成分与转化后的硬件成分连接，形成一个完整的仿真环境。     

基于随机线性二次最优的磁悬浮控制系统

分析电磁型（EMS）磁悬浮列车悬浮系统结构特性的基础上，建立了单磁铁磁悬浮系统的数学模型。采用随机线性二次最优的控制策略设计系统控制器，研究了在不同性能指标加权阵的情况下，该磁悬浮控制系统对具有初始磁间隙和受到外力干扰后磁间隙随时间变化的控制效果，并给出仿真结果，为磁悬浮控制系统的设计提供参考。     

三电平逆变器直接功率控制的拓展算法

阐述了多电平逆变器的控制策略和拓扑结构,并具体分析了三电平逆变器的工作原理。提出了一种基于直接功率控制的算法,协调控制系统的有功功率、无功功率和中点电压。该算法通过3个滞环控制器实现,并分析各个逆变器电压矢量作用后产生的有功、无功、中点电压的变化,从而选择合适的逆变器电压矢量,控制各个IGBT的关断。仿真结果表明：基于该算法的三电平逆变器输出电压与电流波形良好,直流侧电压稳定,同时中点电压滞环控制器抑制了中点电压的波动。     

中药提取过程计算机控制系统的设计与应用

简要介绍用于中药提取过程的计算机控制系统的设计和应用，其中包括提取过程对控制系统的要求、控制系统的硬件设计、控制系统的应用软件设计、系统的应用效果。     

输液泵/注射泵集中控制系统的研制

作者论述了基于CAN总线技术的输液泵/注射泵集中控制系统的结构和工作原理,以及系统软、硬件设计方法等.该系统可同时监视和控制多台输液泵/注射泵的状态信息和控制参数,为临床提供更为周密的输液治疗手段,大大减轻医护人员的工作强度,提高护理和治疗效果.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.     

Possible Spread of adenovirus type 3 from poultry to humans ：indirect evidence from an outbreak in China

Objective:To explore the epidemiology and etiology for an outbreak of acute respiratory tract infection that occurred in one county of Jiangsu Province, China 2004. Methods: Only cases meeting the case definition were included in the study. We reviewed the medical records of the cases who were admitted to the local hospitals, interviewed cases by a standard questionnaire, and then described the epidemiotogic features and analyzed risk factors by means of a case-control study. We collected pharyngeal swab specimens and sent them to different laboratories for isolation and culture. The laboratory used different detection methods such as DIP, PCR, electron microscope examination and microneutralization assay, to identify and then type the positive specimens. Results:A total of 871 cases were reported during the period from April 18 to July 4,2004. The distribution of onset times presented two peaks, one in late May and another in middle June. The epidemic occurred mainly in the elementary and junior high schools in ten townships of one county, and the mean age of the cases was 12 years (range 7 months to 18 years). The course of the disease was acute, and was characterized by fever accompanied with sore throat and tonsillitis. The WBC count of cases was normal or elevated. The mean duration of illness was 5 days (range 2 to 12 days). No fatalities from illness were reported. A case-control study indicated that the possible risk factors were close contact with a case and/or poultry before onset and sharing of towels among members of the family. The typical CPE was observed through inoculating pharyngeal swab specimens into the HEP-2 cell cultures in different laboratories. An infection of adenovirus type 3 was verified by detecting positive specimens in different methods. Conclusion:This investigation demonstrated that the acute respiratory infection in cases was caused by adenovirus type 3. Cases occurred in over 70 schools in ten townships in 2004, and the route of transmission was possibly close contact with cases or droplet transmission.