大面积烧伤患者休克期切痂植皮的护理

目的 探讨大面积烧伤患者休克期切痂植皮的护理。方法 对22例大面积烧伤患者休克期切痂植皮的护理进行回顾性分析。结果 通过落实各项护理措施,提高重症烧伤患者手术成功率。结论 大面积烧伤患者休克期切痂植皮护理措施的落实是护理工作重点。     

两种手术方式治疗深度手烧伤疗效比较

目的通过手深度烧伤切削痂后两种植皮方法比较,探讨深度手烧伤后早期简单有效的治疗方法。方法回顾性分析住院的56例患者手深度烧伤不同手术方式的愈后效果。结果早期削痂后立即植皮和早期削痂3天后植皮,均可获得满意的外观和功能。结论在医师手术经验丰富时,深度手烧伤后早期切削痂立即整张皮片移植是手深度烧伤后首选治疗方式。     

休克期切痂对大面积烧伤病人能量消耗的影响

目的观察休克期切痂植皮对烧伤病人能量消耗的影响。方法对２１例烧伤面积大于３０％的深度烧伤病人,依休克期切痂与否分为休克期切痂植皮组（１５例）和非休克期切痂植皮组（６例）,所有病人在治疗期间应用新型代谢车床旁动态监测病人静息能量消耗（ＲＥＥ）变化。结果休克期切痂植皮组和非休克期切痂植皮组病人在年龄结构、烧伤总面积、Ⅲ度烧伤面积、首次切痂面积等方面基本一致（Ｐ＞０．０５）,尽管两组病人ＲＥＥ均明显升高,２周时休克期切痂组为（３１１±１５）Ｊ·ｈ－１·ｍ－２,非休克期切痂组为（３４５±１６）Ｊ·ｈ－１·ｍ－２。但休克期切痂植皮组由于及时切痂植皮封闭创面,病人在伤后２周内ＲＥＥ明显低于非休克期切痂植皮组,且休克期切痂植皮组病人在切痂前、切痂后ＲＥＥ均显著低于非休克期切痂组。结论严重深度烧伤病人休克期切痂植皮可在一定程度上降低机体的高代谢状态。     

手背深度烧伤早期切痂植皮的治疗体会

目的总结手背深度烧伤（深Ⅱ～Ⅲ°）的治疗经验。方法对2001年1月至2009年12月,我科收治的61例91只手背深度烧伤创面早期切痂植皮手术的临床资料进行回顾性调查分析。结果 91只手均成功施行早期切痂植皮,全部治愈,功能恢复及外形均满意,平均愈合时间18d。术后2例因感染皮片斑块状坏死,经换药愈合。结论早期切痂植皮治疗手背深度烧伤安全可行,技术成熟,疗效可靠,可有效防止瘢痕挛缩,促进手功能恢复。     

538只手背深度烧伤早期修复疗效分析

目的：探讨５３８只手背深度烧伤手术治疗近期疗效及影响因素。方法：拟定术后近期疗铲评估标准,５３８只手背深度烧伤采用切痂、削痂植皮或皮瓣转移修复,分析伤后施行手术时间,烧伤面积和不同致伤因素对手术近期疗效的影响。结果：术后近期优良率为９２．７％（４９９只手）,其优良率与伤后施行手术时间、烧伤面积和致伤因素有直接关系。结论：手背深度烧伤,为确保手功能最大限度地恢复,应在挽救生命的同时早期施行切痂、削痂植皮或皮瓣转移手术。     

早期切痂植皮治疗深度手烧伤的临床研究

目的为解决手部深度烧伤的难题,探讨早期切痂植皮治疗的临床效果。方法总结性回顾2010年5月—2012年5月在该院施行切痂植皮手术手部深度烧伤患者100例,分析临床资料,将其随机分为早期切痂植皮组和延迟切痂植皮组,早期切痂植皮组50例患者,延迟切痂植皮组50例患者,观察两组恢复的效果,针对患者术后出现功能障碍感染、创面愈合时间、植皮成活率不同进行比较,得出结论。结果手术后,早期切痂植皮组患者功能障碍感染出现例数6例,感染率12%,创面愈合时间为(12±5.5)d,植皮成活例数为49例,成活率为98.%,这三项数据均优于延迟组,差异有统计学意义(P<0.05)。结论对手部深度烧伤患者实施早期切痂植皮手术治疗,可减少瘢痕增生,可有效促进手部功能的恢复,保护手功能,重视按摩、理疗等综合性康复治疗,减少并发症,缩短创面愈合时间和住院时间,对患者早期康复有一定的影响。     

大面积深度烧伤休克期切闸植皮的必要性与可行性

大面积深度烧伤后创面的存在是导致机体急性代谢障碍 ,免疫功能下降 ,内分泌紊乱和内脏功能损害的根源 ,也是全身感染的来源地。因此 ,尽早尽多地去除坏死组织 ,并有效覆盖创面是救治大面积深度烧伤的主要手段 ,传统公认的手术时机为伤后 3～ 7天。但近年来对入院较早、复苏满意的大面积深度烧伤病人开展休克期 (伤后 48ｈ内 )切痂植皮手术收到了满意的临床疗效 ,同时进一步探讨了休克期切痂的利弊 ,论证了休克期切痂植皮的必要性与可行性。现对大面积深度烧伤休克期切痂植皮的必要性及可行性进行综述如下。1　开展休克期切痂植皮的必要性1.…     

50例80只手背深度硝火烧伤创面削痂后大张中厚自体皮移植体会

目的探讨手背深度烧伤（深Ⅱ～Ⅲ°）的治疗经验治疗方法。方法对2004年至2011年我院50例患者80只手手背深度烧伤创面早期切、削痂植皮手术的临床资料进行回顾性调查分析。结果 50例80只手全部治愈,其中2例术后因感染,皮片出现斑块状坏死,经换药愈合。结论早期切、削痂植皮治疗手背深度烧伤安全可行,技术成熟,疗效可靠,可有效防止瘢痕挛缩,促进手功能恢复。     

早期切削痂植皮治疗手部深度烧伤

目的 探讨一种治疗手部深度烧伤理想的方法.方法 对2003年1月～2007年9月在本科住院的39例60只手部深度烧伤患者施行早期切(削)痂中厚皮片移植术,并早期指导进行功能锻炼.结果 所有病例均能成功施行手术,45只手植皮全部成活,植皮成活率达75.00%,5只手出现局部皮片下血肿,4只手皮片部分感染,6只手皮片部分坏死,经二期手术植皮后愈合良好,手功能优良率达88.33%.结论 早期切(削)痂植皮术治疗手部深度烧伤疗效可靠,并发症少,可有效防止瘢痕挛缩,促进手功能恢复,最大限度的减少手部深度烧伤致残率,提高患者生活质量,是一种治疗手部深度烧伤理想的方法.     

四肢深度烧伤切削痂植皮治疗的疗效观察

目的：探讨四肢深度烧伤早期切、削痂植皮与晚期切、削痂植皮治疗的治疗效果。方法选取2005年1月-2013年6月云南曲靖市第一人民医院烧伤科收治的四肢深度烧伤患者240例，按患者手术治疗时间分为早期切痂植皮治疗组、早期削痂植皮治疗组、晚期切痂植皮治疗组治疗组、晚期削痂植皮治疗组，各60例。早期治疗组于伤后24～72 h内对患者实施切、削痂植皮手术治疗，晚期治疗组与伤后4～7 d内实施切、削痂植皮手术治疗。比较四组的治疗效果及不良反应发生情况。结果经过手术治疗和术后护理：（1）早期削痂植皮治疗组优良率96.7%明显高于早期切痂植皮治疗组优良率83.3%，差异显著，具有统计学意义（P＜0.05）；（2）晚期削痂植皮治疗组优良率78.3%明显高于早期切痂植皮治疗组优良率61.7%，差异显著，具有统计学意义（P＜0.05）；（3）早期削切、痂植皮治疗组总优良率90.0%明显高于晚期切、削痂植皮治疗组总优良率70.0%，差异有统计学意义（P＜0.01）。结论四肢深度烧伤早期切、削痂植皮的治疗效果要优于晚期切、削痂植皮治疗的治疗效果；对于四肢深度烧伤的患者削痂植皮治疗优于切痂植皮治疗。对于四肢深度烧伤的患者应早期进行削痂植皮的治疗。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…