双歧杆菌三联活菌胶囊联合肠胃康治疗腹泻型肠易激综合征的疗效观察

目的:观察双歧杆菌三联活菌胶囊联合肠胃康胶囊治疗腹泻型肠易激综合征(IBS)的疗效。方法:将64例腹泻型肠易激综合征患者随机分为两组,治疗组和对照组各32例。治疗组口服双歧杆菌三联活菌胶囊3粒,2次/d,肠胃康胶囊2粒,3次/d;对照组口服肠胃康胶囊2粒,3次/d。疗程均为4周,观察两组临床症状改善情况。结果:治疗组临床症状改善明显优于对照组,两组比较差异有统计学意义(P<0.05),两组均未发现明显不良反应。结论:双歧杆菌三联活菌胶囊联合肠胃康胶囊治疗腹泻型肠易激综合征疗效显著。     

温肾止泻方敷脐联合双歧杆菌乳杆菌三联活菌片对腹泻型肠易激综合征的疗效观察

目的观察温肾止泻方敷脐联合双歧杆菌乳杆菌三联活菌片治疗腹泻型肠易激综合征的临床疗效。方法将腹泻型肠易激综合征患者120例,随机分为两组。治疗组采用温肾止泻方敷脐与双歧杆菌乳杆菌三联活菌片联合治疗;对照组采用双歧杆菌乳杆菌三联活菌片单药治疗。结果治疗组总有效率显著高于对照组(P0.05)。两组治疗后腹胀、腹痛评分及日均大便次数均优于治疗前(P0.05),且治疗组优于对照组(P0.05)。两组均未见明显的不良反应。结论温肾止泻方敷脐与双歧杆菌乳杆菌三联活菌片联合治疗总有效率高于单用双歧杆菌乳杆菌三联活菌片,且对腹胀、腹痛及腹泻症状的改善均优于单用双歧杆菌乳杆菌三联活菌片,对腹泻型肠易激综合征的治疗具有很好的疗效。     

硫糖铝片联合双歧杆菌三联活菌胶囊治疗腹泻型肠易激综合征的临床效果

目的:观察硫糖铝片联合双歧杆菌三联活菌胶囊治疗腹泻型肠易激综合征的效果。方法:选取88例腹泻型肠易激综合征患者作为研究对象,按随机数字表法将其分为对照组和观察组各44例,对照组口服双歧杆菌三联活菌胶囊治疗,观察组在对照组的基础上联合硫糖铝片治疗,比较两组临床疗效、临床症状改善情况、复发情况及不良反应发生率。结果:观察组治疗有效率为93.18%,明显高于对照组的77.27%,差异有统计学意义(P<0.05);观察组止泻时间和大便性状好转时间均明显短于对照组,差异有统计学意义(P<0.05);治疗1个月与2个月后,观察组的复发率均明显低于对照组,差异有统计学意义(P<0.05);治疗期间两组不良反应发生率比较差异无统计学意义(P>0.05)。结论:与单用双歧杆菌三联活菌胶囊相比,硫糖铝片联合双歧杆菌三联活菌胶囊治疗腹泻型肠易激综合征,可明显改善患者的临床症状,有效预防复发,且安全性高。     

莫沙必利片配合双歧三联活菌胶囊对肠易激综合征的疗效及对患者血液学指标及肠敏感度的影响

目的:探讨莫沙必利片配合双歧三联活菌胶囊对肠易激综合征的疗效及对患者血液学指标及肠敏感度的影响。方法:选取2017年3月-2019年2月本院收治的94例肠易激综合征患者为研究对象,用随机数字表法随机分为观察组和对照组,每组各47例。对照组给予双歧三联活菌胶囊,观察组在双歧三联活菌胶囊基础上加用莫沙必利片,比较两组患者疗效、血液学指标及肠敏感度。结果:观察组总有效率82.98%高于对照组的63.83%,差异有统计学意义(P0.05);观察组治疗后生长抑素(SS)水平低于对照组、神经肽(NPY)水平高于对照组,差异有统计学意义(P0.05);观察组治疗后TNF-α、IL-6、IL-8低于对照组,差异均有统计学意义(P0.05);观察组治疗后腹痛评分、腹泻评分、总分低于对照组,差异均有统计学意义(P0.05)。结论:双歧杆菌三联活菌胶囊联合莫沙必利片对肠易激综合征疗效显著,可以有效改善血液学指标和肠敏感度,可以推广于临床。     

蒙脱石联合双歧三联活菌治疗肠易激综合征

目的探讨蒙脱石联合双歧三联活菌治疗腹泻型肠易激综合征的疗效。方法将60例腹泻型肠易激综合征患者随机分为二组,观察组30例,男16例,女14例,年龄(41±10)岁,应用蒙脱石3.0g,3次/d加双歧三联活菌胶囊420mg,3次/d口服,对照组30例,男15例,女15例,年龄(39±11)岁,应用单剂蒙脱石3.0g,3次/d口服。疗程均为4周。结果观察组有效率为69.6%,对照组为76.6%,二组比较差异有统计学意义(P<0.05)。结论蒙脱石联合双歧三联活菌治疗腹泻型肠易激综合征有较好疗效。     

双歧三联活菌联合硝苯地平治疗腹泻型肠易激综合征临床分析

目的: 观察双歧三联活菌与硝苯地平联合应用治疗腹泻型肠易激综合征的临床疗效。方法: 将88例随机分为两组,治疗组(双歧三联活菌联合用药组)45例,双歧三联活菌每次4片,每天3次;硝苯地平10 mg,每天3次;对照组43例,双歧三联活菌每次4片,每天3次。两组均治疗2周。结果: 治疗组总有效率82.22%,高于对照组55.81%(P<0.05)。停药4周内复发率分别为21.62%和45.83%,两组差异有统计学意义(P<0.05)。结论: 双歧三联活菌、硝苯地平联合应用治疗腹泻型肠易激综合征有较好疗效和较低的复发率。     

探析肠易激综合征临床特征及治疗效果

目的探析肠易激综合征临床特征及治疗效果。方法本次研究对象为我院2012年3月至2015年3月收治的120例肠易激综合征患者,并随机分成对照组(60例)和观察组(60例)。对照组采取匹维溴铵片治疗,观察组在对照组匹维溴铵片治疗的基础上,增加双歧三联活菌制剂治疗。结果观察组和对照组的治疗总有效率分别为95.00%和73.33%,观察组的治疗总有效率显著高于对照组(P0.05)。结论肠易激综合征的临床症状复杂,最常见的症状为与排便异常相关的腹泻、腹痛和腹胀,临床分型多,匹维溴铵联合双歧三联活菌制剂治疗肠易激综合征的效果显著。     

美常安治疗腹泻型肠易激综合征

目的:评价美常安治疗腹泻型肠易激综合征的临床疗效。方法:将120例腹泻型肠易激综合征患者随机分为治疗组62例和对照组58例,同时行中医辨证分型。治疗组口服美常安0.5g,每日3次;对照组口服双歧三联活菌0.42g,每日3次,饭后服用。疗程14天,观察总体疗效、治疗组各证型疗效及单项症状缓解情况。结果:治疗组总有效率为95.2%,其中脾胃虚弱型为95.8%,肝郁脾虚型为94.4%,脾肾阳虚型为91.7%,湿热瘀阻型为88.9%。结论:美常安、双歧三联活菌对腹泻型肠易激综合征均有效,美常安优于双歧三联活菌。     

复方谷氨酰胺肠溶胶囊治疗腹泻型IBS临床比较

目的比较复方谷氨酰胺肠溶胶囊和双歧三联活菌胶囊治疗腹泻型肠道易激综合征(IBS)的临床效果。方法 69例腹泻型IBS患者随机分为两组,治疗组36例,对照组33例,治疗组采用复方谷氨酰胺肠溶胶囊治疗,对照组采用双歧三联活菌胶囊治疗,观察两组患者的临床治疗效果。结果治疗组显效率为55.6%,对照组显效率为30.3%,治疗组高于对照组,治疗组有效率为86.1%,对照组有效率为72.7%,治疗组高于对照组,随访半年有效率治疗组为80.6%,对照组为57.6%,治疗组高于对照组。结论复方谷氨酰胺肠溶胶囊治疗肠道易激综合征优于芽孢杆菌类制剂,安全方便,具有较好疗效。     

气滞胃痛颗粒联合匹维溴铵治疗腹泻型肠易激综合征临床研究

目的:气滞胃痛颗粒联合匹维溴铵治疗腹泻型肠易激综合征临床效果。方法:选择2016.2-2018.2我院收治的108例腹泻型IBS者为研究对象。依照治疗方式,将其分为2组,每组54例。对照组使用匹维溴铵,观察组使用气滞胃痛颗粒,分析结果。结果:观察组治疗有效率为64.81%,观察组为92.59%。和对照组相比,观察组治疗有效率明显较高,P0.05.治疗前,两组临床症状积分无明显差异,P0.05。治疗后,患者相关症状积分明显改善,就改善程度来讲,相较于对照组,观察组的积分降低更为显著,P0.05。结论:对于腹泻型肠易激综合征者,使用气滞胃痛颗粒联合匹维溴铵治疗,安全性强,能全面降低不良反应发生率,消除患者不良症状,值得进一步推广。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.