面部雀斑伴有黄褐斑患者的完美强脉冲光的临床治疗

目的：评价用完美强脉冲光（OPT）治疗伴有黄褐斑的面部雀斑患者临床疗效及安全性。方法：82例伴有黄褐斑的雀斑患者,全部采用 OPT 治疗5次,间隔3~4周治疗1次,完成5次治疗随访1月后留取治疗前后照片观察疗效,所有患者都要求严格防晒,勿过度劳累。结果：经过5次 OPT 治疗后,雀斑治愈70例（85.36％）;显效9例（10.98％）;雀斑总有效率96.34％（79/82）。黄褐斑治愈0例（0％）;显效51例（62.20％）;黄褐斑总有效率51例62.20％（51/82）。不良反应：有7例（8.54％）出现色素沉着,经过3~6个月后色素明显减淡;有2例（2.44％）出现色素减退,未出现瘢痕。结论：OPT 治疗伴有黄褐斑的雀斑患者安全、高效,大部分雀斑患者治愈,黄褐斑得到明显改善,但黄褐斑治愈率不高仍是一个现实问题,有待我们进一步研究和探讨。     

IPL强脉冲光联合CO2激光治疗酒糟鼻

目的观察IPL强脉冲光联合CO2激光治疗酒糟鼻的临床效果。方法IPL强脉冲光根据鼻部毛细血管的粗细,设定治疗参数,CO2激光采用连续输出波。结果42例酒糟鼻治愈25例,有效12例,无一例无效,总有效率100%。结论酒糟鼻红斑期采用IPL强脉冲光治疗,丘疹期及鼻赘期采用CO2激光联合IPL强脉冲治疗,治疗效果满意。     

强脉冲光联合脉冲染料激光治疗鲜红斑痣的临床疗效分析

目的：探讨强脉冲光（IPL）联合脉冲染料激光（PDL）治疗紫红型和增厚型鲜红斑痣的治疗效果。方法：回顾性分析2004年7月-2007年6月在本院整形美容外科用强脉冲光联合脉冲染料激光治疗紫红型和增厚型鲜红斑痣的患者175例，总结其治疗方案、治疗次数、皮损性质等与疗效的关系以及不良反应的发生。结果：175例紫红型和增厚型患者分别先经IPL治疗3次，再用PDL治疗，治疗间隔2～3月，共经过4～8次的治疗，其治疗8次后总有效率和治愈率分别达到51．43％（90／175）和14．29％（25／175），且4～8次的治疗中，治疗次数越多，活疗效果越好（P〈0．05）。175例患者中，1．14％（2／175）出现增生性瘢痕，1．71％（3／175）出现色素减退，2．86％（5／175）出现色素沉着。结论：强脉冲光（IPL）联合脉；中染料激光（PDL）治疗紫红型和增厚型鲜红斑痣疗效可靠。并发症少、是目前治疗紫红型和增厚型鲜红癍痣的最常见的治疗方法。     

StarLuxG强脉冲光与Q-开关倍频Nd：YAG激光治疗雀斑的疗效对比研究

目的：StarLuxG强脉冲光与Q-开关倍频Nd：YAG激光治疗雀斑的疗效对比研究。方法：50例雀斑患者,随机分为2组,每组25例,StarLuxG组采用StarLuxG强脉冲光,激光组采用Q-开关倍频Nd：YAG激光（波长532 nm）,根据患者皮损深浅选择适当的参数。针对2组间治疗雀斑的总有效率和不良反应采用卡方检验进行比较,P＜0.05,差异有统计学意义。结果：StarLuxG组总有效率 88%;激光组总有效率 92%,差异无统计学意义（ ?字2=2.569,P ＞0.05）;StarLuxG组0例（0%）患者出现暂时性色素沉着;激光组6例（24%）患者出现暂时性色素沉着,差异有统计学意义（ ?字2=6.818,P＜0.05）。随访6~12个月,术后无感染及瘢痕发生。结论：StarLuxG强脉冲光是一种有效、安全、无创便捷的治疗面部雀斑的方法,无停工期,不影响患者的正常生活及工作。     

Q-开关Nd:YAG激光、强脉冲光在黄褐斑临床治疗中的应用效果探讨

目的研究探讨Q-开关Nd:YAG激光联合强脉冲光治疗黄褐斑的临床疗效。方法选择2016年1月～2017年6月期间我院皮肤科收治的100例黄褐斑患者,随机分为两组,每组50例。对照组采用Q-开关Nd:YAG激光治疗,观察组采用Q-开关Nd:YAG激光联合强脉冲光治疗,比较两组临床疗效、不良反应发生率、皮损面积评分、皮肤颜色评分、面部美观满意度、DLQI评分。结果在临床疗效方面,治疗2个月、4个月、6个月后,观察组的总有效率均高于对照组(P0.05)。观察组、对照组的不良反应总发生率分别为8%、4%,组间比较差异无统计学意义(P0.05)。治疗后,两组的皮损面积评分、皮肤颜色评分均较治疗前降低(P0.05),而观察组的皮损面积评分、皮肤颜色评分均低于对照组(P0.05);观察组的面部美观总满意率为88%,高于对照组的70%(P0.05)。治疗后,组间比较,观察组DLQI评分低于对照组(P0.05),而两组DLQI评分均较治疗前显著降低(P0.05)。结论采用Q-开关Nd:YAG激光联合强脉冲光治疗黄褐斑可提高临床疗效,还兼具安全性。     

Q开关Nd：YAG1064nm激光治疗外伤性文身疗效分析

目的观察长脉宽Q开关Nd：YAG激光在外伤性文身治疗中的疗效。方法自2006年1月～2007年12月,利用调Q开关Nd：YAG1064nm激光对13例外伤性文身患者治疗,间隔6～8周以首次相同的脉冲形式重复治疗．并进行疗效观察。结果外伤性文身男性多于女性,交通事故为第一原因,经过Q-开关Nd：YAG激光治疗一次后,皮损均有明显消退,并随治疗次数增多,治愈率明显增高,经过5次治疗,75％的患者治愈,有效率100％．均有很好的疗效。结论Q-开关Nd：YAG激光是治疗外伤性文身安全、有效的方法．不良反应常见的是色素沉着为可逆性,未见有新的疤痕形成。     

Q开关紫翠玉激光和强脉冲光治疗亚洲人雀斑和痣的疗效比较：一项随机、医生单盲、左右面部比较研究

背景：Q开关（QS）有色激光和强脉冲光（IPL）均能成功治疗色素性疾病。目的：旨在比较QS紫翠玉激光（QSAL）和IPL治疗亚洲人雀斑和痣的疗效和副作用。方法：共15例雀斑患者和17例痣患者被随机予以一侧面颊一疗程QSAL和间隔4周后对侧面颊两疗程IPL．采用一种新的色素面积与严重度指数评分来评价疗效。结果：所有患者均有改善（P〈0．0001）。1例雀斑患者和8例痣患者经QSAL治疗后发生炎症后色素沉着。而IPL治疗后未出现炎症后色素沉着。     

强脉冲光治疗面部色素性病变136例观察

目的：探讨强脉冲光对面部色素性病变的治疗效果。方法：采用采韵光子嫩肤仪波长为560nm—1200nm滤光片治疗136例面部色素性病变患者,治疗2次～6次,每次时间间隔为3W-5W,每位患者进行对比拍照、记录参数并进行临床疗效评估。结果：128例患者中各种病变的显效率分别：雀斑77．8％（70／90）,痤疮后色素沉着斑点80％（8／10）,扁平疣色素沉着80％（4／5）,老年斑62．5％（5／8）,咖啡斑50％（4／8）,黄褐斑效果不明显。结论：强脉冲光对雀斑、痤疮后色素沉着斑、扁平疣色素沉着有良好的疗效。     

Q-开关Nd:YAG激光治疗黄褐斑的效果观察

目的:探讨Q-开关Nd:YAG激光治疗黄褐斑的方法和效果.方法:采用美国HOYA-conBio公司生产的Medlite C6Q开关Nd:YAG激光美肤系统,波长1064nm,光斑6～8 mm,能量2.3～3.5 J/cm2,每周1次,共10～15次,治疗黄褐斑32例,完成治疗后判断疗效.基本治愈5例(15.6%),显效17例(53.1%),好转9例(28.1%),无效1例(3.1%),前两者之和为总有效率,达68.7%.结论:Q-开关Nd:YAG激光是治疗黄褐斑的一种安全有效的方法.     

IPL联合脉冲染料激光治疗痤疮疗效观察

目的　研究IPL联合５８５nm 脉冲染料激光治疗痤疮的临床疗效.方法　１００例痤疮患者随机分为２组,每组５０例,分别使用IPL及IPL联合VP５８５疗 法.其中IPL组采用以色列飞顿公司生产的lovelyII型光子治疗仪,联合治疗组予以IPL联合美国Synosure公司生产的５８５nm 脉冲染料激光治疗仪.治疗期间 每６次为１个疗程,每次治疗间隔时间为２６至３８天.结果　IPL组有效率为７０％(５０例),联合治疗组有效率为８８％(５０例),两组相比差异具有显著性统计学意 义(p＜０．０５);联合治疗组有效率明显高于IPL组.结论　IPL联合５８５nm 脉冲染料激光可显著提高痤疮的治疗效果.     

Q—开头多波长激光治疗皮肤色素性病变临床应用研究

目的：观察Q-开头多波长激光治疗皮肤色素性病变的疗效。方法：采用Q-开头多波长激光机（QS1064、QS755、QS532）治疗不同的皮肤色素性病变685例。结果：Q-开头多波长激光机治疗各种皮肤色素性病变有效率达100%。结论：Q-开头多波长激光治疗各种皮肤色素性病变，操作简单。安全可靠，不留瘢痕，是目前最好的治疗方法。     

激光治疗皮肤色素痣的1 882例临床分析

目的 对不同激光治疗皮肤各类色素痣进行临床评价。方法 根据需要选用CO2激光、Q开关翠绿宝石激光或Q开关Nd:YAG激光对皮肤各种先天性、后天性色素痣进行汽化或扫描。结果 1882例各类皮肤色素痣经激光治疗,全部痊愈。不同种类色素痣所需治疗次数不尽相同,最短1－2次即可治愈,最长需6－7次。结论 激光治疗皮肤色素痣具有治愈率高、副作用少特点,值得推广应用,但不同种类色素痣应采用不同种类激光以提高其安全性。     

Q开关红宝石激光治疗早期脂溢性角化病的疗效和安全性评价

目的评价Q开关红宝石激光治疗早期脂溢性角化病的效果和安全性。方法将85例患者随机分成2组,分别采用Q开关红宝石激光和超脉冲CO2激光治疗,比较2组的疗效和副作用。结果治疗组疼痛感低于对照组,脱痂时间短于对照组,2组治疗效果差别无统计学意义;治疗组的色素沉着发生率和瘢痕形成均低于对照组,2组色素减退率差别无统计学意义。结论 Q开关红宝石激光治疗早期脂溢性角化病效果好、安全性高,值得临床推广。     

应用MEDLITE脉部激光脱毛100例临床观察

目的　观察激光脱毛的临床效果。方法　应用Q开关Nd :YAG固体脉冲对 1 0 0例面部、躯干、四肢多毛患者进行治疗 ,波长选择 1 0 6 4nm ,光斑选择 8～ 6nm ,对应能量为 2 2～ 3 8J/cm2 。每 3～ 4周脱毛 1次。结果　 1 0 0例患者分别脱毛 3～ 7次 ,均达到理想的脱毛效果 ,无任何副作用。结论　MEDLITE四波长激光脱毛效果可靠 ,是目前较好的一种脱毛方法     

口服氨甲环酸片联合Q开关1064 nm Nd:YAG激光治疗黄褐斑临床疗效观察

目的 观察口服氨甲环酸片联合Q开关1064 nm Nd:YAG激光对面部黄褐斑的临床疗效及应用价值。方法选取在本院确诊的黄褐斑患者200例为研究对象,采用回顾性分析的方法将其分为治疗组和对照组,每组各100例。治疗组采用口服氨甲环酸片加Q开关1064 nm Nd:YAG激光联合治疗,对照组仅予以Q开关1064 nm Nd:YAG激光治疗。每次激光治疗间隔周期为4周,共治疗6个周期,并随访6个月,观察治疗后临床疗效、复发及不良反应等情况,并对结果进行统计分析。结果治疗组总有效率为81%,对照组为52%,治疗组对黄褐斑的治疗疗效较对照组占明显优势(P<0.05),且无明显不良反应。治疗组复发率为4%,对照组复发率为12%,治疗组的远期疗效优于对照组。结论口服氨甲环酸片联合Q开关Nd:YAG激光治疗面部黄褐斑疗效佳,值得临床推广应用。     

Clinical Evaluation of Color Doppler Ultrasound in Selecting the Optimal Treatment Modality for Infantile Hemangioma△

Objective We investigated the efficacy and safety of 1064 nm Nd: YAG laser, intense pulsed light (IPL), and lauromacrogol injection in the treatment of hemangioma, in order to evaluate the value of color Doppler ultrasound guidance in choosing the optimal treatment modality. Methods Infantile patients who were clinical diagnosed as hemangiomas were randomly divided into group A, who had color Doppler ultrasound examinations before the treatment, and group B who had the treatment without ultrasound evaluation. Patients in the group A were assigned into subgroups according to the depth of lesion by sonography: group A-1 for those who had a lesion depth <1.2 mm, and took intense pulsed light therapy; group A-2 for those who had a lesion depth ≥1.2mm and < 3 mm, and took long pulse 1064 nm Nd:YAG laser therapy; group A-3 for those who had a lesion depth ≥3mm and <5 mm, and were treated by IPL combined with long pulse 1064 nm Nd:YAG laser treatment; Group A-4 for those who had a lesion depth ≥5 mm, and took lauromacrogol injection therapy. Patients in the group B took long pulse 1064 nm Nd:YAG laser treatment without preoperative ultrasound evaluation. The efficacy and adverse reactions of the treatments between the groups were evaluated and compared statistically.Results Totally 113 patients with 128 skin lesions were enrolled in this study, 85 in the group A (mean age 6.8±7.9 months) and 28 in the group B (mean age 6.9±9.9 months). The mean depth of hemangioma was 3.3±1.1 mm in the group A, ranging from 0.5-7.8 mm, with 0.8±0.4 mm, 2.2±0.4 mm, 4.2±0.6 mm and 6.2±0.7 mm in group A1, A2, A3 and A4, respectively. The cure rates and effective rates in the group A were significantly higher than those in the group B (cure rates: 64.5% vs 56.3%, U=3.378, P=0.045; effective rates: 89.5% vs 78.1%, U=4.163, P=0.041). The adverse effect rates of the group A (vesicle 20.0%, pigmentation 46.9%, scarring 17.7%) were lower than those of the group B (vesicle 21.9%, pigmentation 60.4%, scarring 25.0%). Incidences of pigmentation and scarring were statistically significantly different (U=3.884, P=0.034, and U=4.016, P=0.032 respectively) between the two groups.Conclusion With the guidance of color Doppler ultrasound, the efficacy and safety of long pulse 1064 nmNd:YAG laser, intense pulsed light, and lauromacrogol injection in the treatment of infantile hemangioma have better outcomes compared to laser treatment alone without preoperative ultrasound examination.     

Clinical Evaluation of Color Doppler Ultrasound in Selecting the Optimal Treatment Modality for Infantile Hemangioma

Objective We investigated the efficacy and safety of 1064 nm Nd: YAG laser, intense pulsed light (IPL), and lauromacrogol injection in the treatment of hemangioma, in order to evaluate the value of color Doppler ultrasound guidance in choosing the optimal treatment modality. Methods Infantile patients who were clinical diagnosed as hemangiomas were randomly divided into group A, who had color Doppler ultrasound examinations before the treatment, and group B who had the treatment without ultrasound evaluation. Patients in the group A were assigned into subgroups according to the depth of lesion by sonography: group A-1 for those who had a lesion depth <1.2 mm, and took intense pulsed light therapy; group A-2 for those who had a lesion depth≥1.2mm and < 3 mm, and took long pulse 1064 nm Nd:YAG laser therapy; group A-3 for those who had a lesion depth≥3mm and <5 mm, and were treated by IPL combined with long pulse 1064 nm Nd:YAG laser treatment; Group A-4 for those who had a lesion depth≥5 mm, and took lauromacrogol injection therapy. Patients in the group B took long pulse 1064 nm Nd:YAG laser treatment without preoperative ultrasound evaluation. The efficacy and adverse reactions of the treatments between the groups were evaluated and compared statistically. Results Totally 113 patients with 128 skin lesions were enrolled in this study, 85 in the group A (mean age 6.8±7.9 months) and 28 in the group B (mean age 6.9±9.9 months). The mean depth of hemangioma was 3.3±1.1 mm in the group A, ranging from 0.5-7.8 mm, with 0.8±0.4 mm, 2.2±0.4 mm,4.2±0.6 mm and 6.2±0.7 mm in group A1, A2, A3 and A4, respectively. The cure rates and effective rates in the group A were significantly higher than those in the group B (cure rates: 64.5%vs 56.3%,U=3.378, P=0.045; effective rates: 89.5%vs 78.1%,U=4.163,P=0.041). The adverse effect rates of the group A (vesicle 20.0%, pigmentation 46.9%, scarring 17.7%) were lower than those of the group B (vesicle 21.9%, pigmentation 60.4%, scarring 25.0%). Incidences of pigmentation and scarring were statistically significantly different (U=3.884,P=0.034, andU=4.016,P=0.032 respectively) between the two groups. Conclusion With the guidance of color Doppler ultrasound, the efficacy and safety of long pulse 1064 nmNd:YAG laser, intense pulsed light, and lauromacrogol injection in the treatment of infantile hemangioma have better outcomes compared to laser treatment alone without preoperative ultrasound examination.     

Q开关Nd:YAG 1064 nm和532 nm波长激光照射对豚鼠血液流变性的影响

【目的】研究Q开关Nd :YAG 10 6 4nm和 5 32nm波长激光照射对豚鼠血液流变性的影响 ,了解所产生的生物学效应。【方法】波长为 10 6 4nm和 5 32nm各自 3种不同剂量的激光体外照射豚鼠。测定豚鼠血液黏度等 6项血液流变学指标。【结果】波长 10 6 4nm的两种大剂量和波长 5 32nm的最大剂量Q开关Nd :YAG激光体外照射豚鼠使高、中、低切变率下的全血黏度和血浆黏度升高 ,红细胞变形指数下降和聚集指数升高 ,其余 3种剂量的激光体外照射对血液流变性无显著改变。【结论】 10 6 4nm波长的Q开关Nd :YAG激光照射在一定剂量下可以改变血液流变性 ,选择合适的剂量可将血液流变性的影响降至最低     

激光治疗皮肤血管瘤病人临床观察与护理

目的探讨三种不同波段激光治疗皮肤血管瘤的临床疗效及护理。方法选择200例患者,分别为1～2cm2表浅血管瘤155例、3cm。以上深在血管瘤45例,其中有草莓状血管瘤120例,根据病程在合适时机选择1064nm激光、595nm激光或（1064＋595）nm激光联合治疗方法,观察治疗效果,探讨应用激光治疗血管瘤的有效方法与护理注意事项。结果1～2cm。内的表浅型血管瘤体,1～3次的病灶清除率在25．80％～95．48％;3cm2以上的深在病灶,5次病灶清除率在80％,其中草莓状血管瘤3次病灶清除率在60％以上。结论应用激光治疗血管瘤,治愈率高,痛苦小,不留瘢痕,效果较好。治疗过程中通过行耐心、细致的护理,可缓解患者紧张,减轻治疗痛苦,对治疗有一定辅助作用。