苯扎溴铵治愈跖疣1例

寻常疣发生于足底者称为跖疣,由人乳头瘤病毒引起,发病与局部压迫、摩擦、外伤、多汗等因素有关,疣病患者多采用过多种方法而久治不愈.运用苯扎溴铵溶液治疗寻常疣,用药5～7 d后,疣体均干枯、脱落[1],因而笔者联想到可否用于治疗跖疣.     

苯扎溴铵治愈跖疣1例

寻常疣发生于足底称为跖疣，由人乳头瘤病毒引起，发病与局部压迫、摩擦、外伤、多汗等因素有关，疣病患多采用过多种方法而久治不愈。运用苯扎溴铵溶液治疗寻常疣，用药5-7d后，疣体均干枯、脱落，因而笔联想到可否用于治疗跖疣。用苯扎溴铵溶液治愈跖疣1例，现报道如下：[第一段]     

转移因子注射液治疗多发性顽固性跖疣30例

跖疣是由乳头瘤空泡病毒所致的一种皮肤病，系发生于足底的寻常疣，外伤和摩擦可为发病的诱因，足部多汗与跖疣的发生也有一定的关系，部分跖疣(镶嵌疣)病程迁延，顽固难治。我科于2002年10月～2003年10月。使用转移因子注射液治疗多发性顽固性跖疣患者30例，收到了较好的临床效果，现报告如下。     

局部注射聚肌胞治疗36例多发性跖疣临床观察

跖疣易发生于足底或趾间等受压部位,多由人类乳头瘤病毒HPV-1感染所致,呈增生性损害。我们用局部注射聚肌胞于疣体基底部治疗跖疣,效果满意,现报告如下。     

艾灸阿是穴对多发性跖疣患者细胞免疫功能的调节作用

跖疣系由人类乳头瘤病毒(Human papilloma virus,HPV)引起的足底皮肤新生物.HPV感染的机理目前尚不完全清楚,已知机体免疫状态与生殖器疣的发生、自然消退、对治疗的反应及恶性转化相关.目前临床上还没有根治HPV的方法,常用的治疗方法大多为去除外生性疣,还不能解决亚临床感染问题,也不能解决复发问题.因此,我们在临床上对多发性跖疣采用艾灸治疗,旨在通过调节免疫功能达到治疗目的.     

电离子机与微波疗法治疗多发性跖疣的对照观察

发生在足底的寻常疣称为跖疣。因其发生在足底或趾等受压部位，损害较深，治疗有一定难度，尤其是多发、融合性皮损更不易一次性治愈。治疗的方法很多。包括刮除术、激光疗法、冷冻疗法、微波疗法、中医等，但都有一定的复发率。我们从2003～2005年采用电离子机与微波疗法治疗多发性跖疣共92例，现将结果报道如下。     

聚肌胞结合CO2激光治疗泛发性跖疣

目的：探讨泛发性跖疣的治疗方法。方法：将60例泛发性跖疣患者随机分为3组,分别采用聚肌胞疣体基底部注射结合CO2激光疣体打洞或3%甲醛（福尔马林）溶液浸泡患侧足底或CO2激光烧灼去除疣体治疗。结果：聚肌胞结合CO2激光治疗泛发性跖疣治愈率明显高于对照组。结论：聚肌胞结合CO2激光治疗泛发性跖疣值得在临床上推广。     

5-氟尿嘧啶治疗糖尿病患者合并跖疣1例

<正>跖疣是发生在足底的一种皮肤浅表良性赘生物,是因感染人类乳头瘤病毒(human papilloma virus,HPV)引起的临床上常见的皮肤病。糖尿病患者免疫缺陷状态下,疣的发病率增高[1]。糖尿病患者合并跖疣传统的治疗方法包括:冷冻、电灼、刮除联合激光、注射等,这些治疗方法易复发,由于血糖高常常导致跖疣愈合迟缓或不愈合。本研究采用5-氟尿嘧啶(5-FU)注射液外敷治疗糖尿病患者合     

跖疣综合治疗

跖疣是足底皮肤上的寻常疣,局部治疗［１］效果不理想,复发率较高。１９９５年１月至１９９６年３月,作者采用全身综合疗法治疗跖疣,取得满意效果。材料与方法病例选择７１例跖疣患者分治疗组和对照组,治疗组聚肌胞加人脾转移因子３８例,对照组聚肌胞加利多卡因３３...     

中药外洗配合西医治疗跖疣35例

跖疣是寻常疣发生于跖部者，中医称为足瘊，本病是人类乳头瘤病毒所引起，常好发于足部着力点，外伤和摩擦可为其发病的诱因，足部多汗与跖疣的发生也有一定的关系。本病好发于足跟、跖骨头或跖问受压处，有时可在胼底的基底上发生。笔者采用中西医结合的方法治疗跖疣取得较满意的疗效，现总结如下。     

T4交感神经干切断术治疗原发性手足多汗症对足汗的影响

目的：观察胸腔镜下T4交感神经干切断术治疗原发性手足多汗症后对足汗的影响。方法：收集2009年6月至2014年5月接受胸腔镜下双侧T4交感神经干切断术治疗原发性手汗症患者28例。在手术前后患者完成有关多汗症的调查问卷并予以评分。术后1个月至半年连续随访足汗症状缓解情况。结果：患者均顺利完成双侧同期胸腔镜下T4交感神经干切断术。术后所有病例手汗症状完全缓解,随访期间未发现手汗症复发。术后1个月足汗症状缓解率28.6%(8/28),但随后足汗的症状再次复发;术后6个月,无患者表现足汗的症状缓解。27例(96.4%)患者对于手术效果非常满意,1例(3.6%)患者认为手术效果比较满意,没有患者不满意或后悔接受手术治疗。结论：胸腔镜下T4交感神经干切断术虽然早期缓解部分原发性手足多汗症患者足汗症状,但效果不能长久维持;不能用该术式来治疗单纯的足汗症。     

Comparison of electrosurgery by electrodessication versus cryotherapy by liquid nitrogen spray technique in the treatment of plantar warts

BackgroundWarts or verrucae are benign proliferations of the skin and mucosa resulting from infection with papilloma viruses. Warts form a small subset of patients attending skin out-patient department (OPD), out of which the plantar warts are one of the common presentation. The present study is an attempt to compare two modalities of treatment that is electrosurgery and cryotherapy in patients with plantar warts. There are no studies available where comparison of complications between two modalities has been done in plantar warts thus making it one of unique studies of its kind.MethodsA prospective, comparative study was conducted over a period of 6 years. After exclusion criteria, one hundred forty-seven male patients having plantar warts were included in the study. Selection of patients suffering from warts subjected to treatment was done by simple random selection. After treatment, 39 patients were lost to follow-up, and finally 48 patients treated by electrosurgery and 60 by cryotherapy were compared and analysed statistically for response to treatment and incidence of complications.ResultsThe overall clearance rate was 75% in electrosurgery versus 73.3% in cryotherapy patients. The pain, delayed wound healing and scarring were observed significantly in more patients treated with electrosurgery than cryotherapy. In our study, recurrence at 24 weeks was observed in 21.9% of the electrosurgery patients which was slightly higher than cryotherapy, where it was 16.6%.ConclusionThis study highlighted that cryotherapy is quick, safe and comparatively painless procedure with less complications with success almost similar to electrosurgery making it more suitable for plantar warts.     

腔镜胸交感神经手术的进展

胸交感神经手术是治疗许多交感神经相关疾病的有效方法。现阶段这一手术多用于治疗多汗症（手足多汗症,头面多汗症,腋汗症等）和面部潮红。1920年Kotzareff首先应用胸交感神经切除术治疗手汗症并获得成功。目前绝大多数胸外科医师所采用的方式是常规胸腔镜交感神经手术（endoscopic thoracic sympathectomy, ETS）。近年来,ETS方式得到了进一步的改良和提高,本文对ETS的各种方式进行总结和讨论。     

Injectable botulinum toxin as a treatment for plantar hyperhidrosis: a case study

Hyperhidrosis is defined as excessive and uncontrollable sweating due to overactivity of the eccrine sweat glands. The first line of treatment for plantar hyperhidrosis consists of conservative therapies such as topical solutions (ie, antiperspirant applications and aluminum chloride preparations) and iontophoresis. When the patient has failed these standard treatments, the other available medical options are rather limited and not well tolerated. Botulinum toxin type A (Botox, Allergan Inc, Irvine, California) is a purified neurotoxin complex approved by the US Food and Drug Administration in 2004 for multiple medical conditions, including severe primary axillary hyperhidrosis that failed conservative topical therapies. Few recent clinical studies have suggested that botulinum toxin is effective in the treatment of plantar hyperhidrosis. In this case study, two patients received intradermal injections of botulinum toxin type A into the plantar aspect of both feet. A 3-month follow-up evaluated the efficacy of botulinum toxin type A by subjectively assessing the amount of residual sweating. In these two patients, botulinum toxin type A was an effective and safe treatment for plantar hyperhidrosis.     

人类乳头瘤病毒结构多肽的电泳分析

用SDS-聚丙烯酰胺凝胶电泳对从寻常疣、蹠疣组织中提取的人类乳头瘤病毒(human papillomavirus,HPV)的结构蛋白进行了分析,初步测定了每条蛋白多肽的分子量。HPV的电泳分析结果表明来自寻常疣、蹠疣的HPV具有不同的结构蛋白图型,其主要和次要衣壳蛋白多肽的分子量具有明显的差异。     

Homeopathic treatment of plantar warts.

OBJECTIVE: To evaluate the efficacy of a homeopathic treatment of plantar warts. DESIGN: Randomized double-blind placebo-controlled trial. SETTING: Hospital-based family medicine unit. PATIENTS: Patients were recruited from the unit, through advertisements in the local media and through personal contacts with colleagues. Of the 853 people screened between December 1987 and January 1989, 174 met the eligibility criteria (age 6 to 59 years and presence of one or more plantar warts untreated during the previous 3 months) and agreed to participate; 162 (93%) completed the 18-week follow-up. INTERVENTIONS: The 6-week homeopathic treatment consisted of thuya 30 "centésimal hahnemannien" (CH) (one tube containing 200 pellets weekly), antimonium crudum 7 CH (5 pellets daily) and nitricum acidum 7 CH (one tube containing 200 pellets daily). The placebo pellets were identical to the treatment pellets in appearance and taste. MAIN OUTCOME MEASURE: The proportion of healed patients; a patient was considered healed if all of the warts had disappeared. MAIN RESULTS: The rates of healing at 6, 12 and 18 weeks were 4.8%, 13.4% and 20.0% respectively in the homeopathic treatment group and 4.6%, 13.1% and 24.4% in the placebo treatment group. CONCLUSION: The homeopathic treatment was no more effective than the placebo treatment of plantar warts.     

电离子治疗仪治疗多发性跖疣的临床疗效观察

目的:评价电离子治疗仪治疗多发性跖疣的临床疗效和安全性。方法:选择96例多发性跖疣患者,随机分为治疗组与对照组,每组48例。治疗组患者采用电离子治疗仪治疗,1次/月,连续治疗2~3次;对照组患者采用液氮冷冻,1次/月,连续治疗2~3次。结果:治疗组患者治疗后治愈率为60.42%,显效率为33.33%,进步率为6.25%,无效率为0%,总有效率为93.75%;对照组患者治疗后治愈率为41.67%,显效率为31.25%,进步率为27.08%,无效率为0%,总有效率为72.92%。治疗组与对照组疗效比较差异有统计学意义(x2=6.075,P=0.014)。两组患者均无明显不良反应。结论:电离子治疗仪治疗多发性跖疣是安全的、有效的。     

液氮冷冻联合中药泡洗对不适合激光及手术治疗的多发性跖疣热瘀互结证患者的效果分析

目的探究液氮冷冻联合中药泡洗对不适合激光及手术治疗的多发性跖疣热瘀互结证患者的效果。方法选取2018年6月至2019年12月本院收治的不适合激光及手术治疗的54例多发性跖疣热瘀互结证患者,根据电脑随机盲选法分为冷冻组和联合组,每组27例。冷冻组给予液氮冷冻治疗,联合组在冷冻组治疗的基础上,加用中药泡洗治疗。比较两组患者皮损状态及生活质量。结果治疗后,联合组皮损评分低于冷冻组(P<0.05),日常生活、工作学习、人际关系、社会活动、自我感觉评分均低于冷冻组(P<0.05),联合组治疗总有效率高于冷冻组(P<0.05)。结论液氮冷冻联合中药泡洗治疗跖疣热瘀互结证多发性患者的效果确切,可促进皮损状态恢复,提升患者生活质量,临床应用价值较高。     

中药外洗联合肌注卡介菌多糖核酸治疗多发性跖疣

目的：观察中药外洗联合肌注卡介菌多糖核酸治疗多发性跖疣的疗效。方法选取我院收治的94例多发性跖疣患者,按照随机数字表法分为对照组和观察组,各47例,对照组给予肌注卡介菌多糖核酸治疗,观察组则加用中药外洗联合治疗,均连续治疗4周。比较2组临床疗效,记录治疗前后疣体的个数、直径变化及平均脱落时间。结果观察组总有效率89.4%,对照组为68.1%（P ＜0.05）;观察组疣体个数减少更明显,直径缩小更显著,平均脱落时间显著短于对照组（P ＜0.05）;观察组复发率8.5%显著少于对照组的27.7%（P＜0.05）。结论中药外洗联合肌注卡介菌多糖核酸治疗多发性跖疣,能减少疣体数目,缩小直径,缩短脱落时间,用药安全性高,复发率低。     

草分枝杆菌注射液联合冷冻治疗多发性跖疣疗效观察

目的探讨草分枝杆菌F.u.36注射液联合冷冻治疗多发性跖疣的临床疗效。方法将门诊多发性跖疣患者随机分成两组,治疗组78例,肌肉注射草分枝杆菌注射液1.72μg,1次/周,同时配合冷冻,1次/月;对照组64例,应用冷冻治疗,1次/月。2～3个月为1疗程。结果治疗组有效率88.46%,对照组为70.31%。两组差异有统计学意义（P〈0.01）。结论草分枝杆菌注射液联合冷冻治疗多发性跖疣疗效高、复发率低、安全、无不良反应。