131I治疗甲状腺功能亢进症对生育的影响临床研究进展

甲状腺功能亢进症是一种常见的内分泌系统疾病,患者常存在下丘脑-垂体-性腺轴功能紊乱,病因多种,目前公认疗效肯定的甲状腺功能亢进症治疗方法主要有3种,抗甲状腺药物(ATD)治疗、131I治疗和甲状腺次全切术.     

131Ⅰ治疗甲状腺功能亢进症对生育的影响临床研究进展

甲状腺功能亢进症是一种常见的内分泌系统疾病,患者常存在下丘脑-垂体-性腺轴功能紊乱,病因多种,目前公认疗效肯定的甲状腺功能亢进症治疗方法主要有3种,抗甲状腺药物(ATD)治疗、131I治疗和甲状腺次全切术。1942年Hertz等开创性地应用131I治疗甲状腺功能亢进症患者,早期由于顾虑131I对性腺的不良影响,曾规定年龄<35岁的甲状腺功能     

甲亢诊断与治疗的现状

甲状腺疾病是内分泌系统最常见和多见的疾病,任何年龄均可发病,女性多见,常引起临床各学科的关注,其中又以甲状腺功能亢进症(甲亢)最多见.甲亢是一种临床综合征,多种病因可以引发,以甲状腺器官特异性自身免疫性疾病最常见.目前甲亢治疗仍以内科治疗、外科手术治疗和131碘放射性同位素治疗三大类方法为主,各有其适应症和存在问题.本文主要论述自身免疫性甲亢的诊治现状.     

浅谈甲状腺术前术后护理

甲状腺疾病在普外科中是一种常见的疾病,尤其是甲状腺腺瘤、结节性甲状腺肿较为多见.甲状腺疾患包括甲状腺肿、甲状腺良恶性肿瘤、甲状腺功能亢进等.手术治疗有较好的疗效.根据多年的临床经验针对不同的病因,总结了甲状腺病人的术前术后护理.     

甲状腺功能亢进的治疗

甲状腺功能亢进症(hyperthyroidism,简称甲亢)是指由多种病因导致体内甲状腺激素分泌过多,引起以神经、循环、消化等系统兴奋性增高和代谢亢进为主要表现的一组疾病的总称.目的 讨论甲状腺功能亢进的治疗.方法 配合诊断进行治疗.结论 甲状腺功能亢进的治疗分外一般治疗、药物治疗与手术治疗.     

16例甲减患者病因临床观察

甲状腺功能减退症是内分泌综合征，病因复杂繁多，相同的甲状腺疾病表现为不同的甲状腺功能，如果不能对甲状腺疾病作出正确诊断，极易造成漏诊误诊，治疗不当，易引起继发性甲减，为进一步提高对本病的认识，降低其发病率，现将16例病因及误诊进行分析。     

夏枯草治疗甲状腺疾病的临床应用及药理作用研究进展

<正>甲状腺疾病是内分泌系统的一种常见疾病,是由多种原因造成的甲状腺功能异常和形态改变,常见分类主要包括甲状腺功能亢进、甲状腺功能减退、甲状腺炎、甲状腺良/恶性肿~([1])。近年来,甲状腺疾病发病率逐年上升,我院中医外科在诊治甲状腺疾病方面形成了中西医结合治疗的特色和优势,开发出3个用于治疗甲状腺疾病的医院制剂,分别为消瘿丸、平潜丸和益气养阴丸,其处方组成中均     

甲状腺功能减退症的中医临床治疗体会

甲状腺功能减退症是目前比较难治愈的一种疾病,近年来研究以中医药辨证论治来治疗该类疾病的研究者日益增多,而且运用中药方剂针对甲状腺功能减退症中的某些类型达到了较好的疗效,运用中西医结合处理一些并发症也颇具良效。多位学者运用中药治疗甲状腺功能减退症在临床上面取得了比较的疗效。     

外科治疗甲状腺机能亢进症938例

甲状腺机能亢进症（以下称甲亢）是临床上比较常见的一种内分泌腺疾病,其发生率男性为0.2%,女性为0.5%～2%,其病因、发病机制至今尚未完全明确,多数学者认为是一种自身免疫性疾病.笔者结合1980～2003年本院手术治疗甲亢938例的临床资料,总结分析如下.     

醛固酮拮抗剂治疗扩张性心肌病50例的临床观察

扩张性心肌病（DCM）是一种以心腔扩大、心肌收缩功能障碍为主要特征的原因不明的心肌疾病，其病因和发病机制仍不十分清楚，尚无特异性治疗方法。但近几年来，醛固酮受体拮抗剂在治疗扩张性心肌病中的作用受到国内外学者的普遍重视。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…